Results 111 to 120 of about 71,388 (222)

Cb1 Enhanced Osteogenic Differentiation Of Bmscs By Rescue Mitochondrial Metabolism

International Dental Journal
Aim or purpose: CB1 is the main effector of endogenous cannabinoid system, and our previous study verified CB1 enhanced the osteo/dentinogenic differentiation of dental mesenchymal stem cells (MSCs), which might be a target for alveolar bone regeneration.
Wanhao Yan
doaj   +1 more source

Ossification of the cranium of Inpaichthys kerri (Characiformes: Acestrorhamphidae) with discussion of paedomorphic traits in the genus

Journal of Anatomy, Volume 248, Issue 5, Page 806-829, May 2026.
In this study, we present a detailed description of the cranial development of Inpaichthys kerri (Characiformes: Acestrorhamphidae), highlighting important topics such as pedomorphic characters and their relationship with ontogeny and phylogeny, as well as ossification sequences unique to the species. Abstract The study of development provides valuable
Yasmim De Santana Santos, Manoela M. F. Marinho   +1 more
wiley   +1 more source

Cannabinoid type-1 receptors in CaMKII neurons drive impulsivity in pathological eating behavior

Molecular Metabolism
Objectives: Overconsumption of palatable food and energy accumulation are evolutionary mechanisms of survival when food is scarce. These innate mechanisms becom detrimental in obesogenic environment promoting obesity and related comorbidities, including ...
Elena Martin-Garcia, Laura Domingo-Rodriguez, Beat Lutz, Rafael Maldonado, Inigo Ruiz de Azua   +4 more
doaj   +1 more source

The Endocannabinoid System Differentially Regulates Escape Behavior in Mice

Frontiers in Behavioral Neuroscience, 2017
Among the hardwired behaviors, fear or survival responses certainly belong to the most evolutionary conserved ones. However, higher animals possess the ability to adapt to certain environments (e.g., novel foraging grounds), and, therefore, those ...
Andreas J. Genewsky, Carsten T. Wotjak
doaj   +1 more source

A Fully Soft Sensing Suit With Optimal Sensor Placement for Real‐Time Motion Tracking

Advanced Intelligent Systems, Volume 8, Issue 4, April 2026.
A fully soft, skin‐conformable sensing suit integrating stretchable sensors, liquid metal wiring, and soft electrodes was developed using direct ink writing, with sensor placement optimized through an automated algorithmic pipeline. This system enables accurate and unobtrusive real‐time motion tracking, providing a scalable, material‐based solution to ...
Jinhyeok Oh, Joonbum Bae
wiley   +1 more source

UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Migraine

Brain and Behavior, Volume 16, Issue 4, April 2026.
This case series followed patients receiving medicinal cannabis for migraine headache for up to 2 years. At 24 months, there were significant improvements in measures assessing headache impact, anxiety, sleep quality, and general quality of life. Note that 15.27% of patients reported an adverse event, most of which were mild or moderate in severity ...
Lennon Hooper, Simon Erridge, Evonne Clarke, Katy McLachlan, Ross Coomber, Augustin Iqbal, James J. Rucker, Mark W. Weatherall, Mikael H. Sodergren   +8 more
wiley   +1 more source

Fenofibrate Recognition and Gq Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1

Advanced Science
The G‐protein‐coupled human cannabinoid receptor 1 (CB1) is a promising therapeutic target for pain management, inflammation, obesity, and substance abuse disorders.
Tianxin Wang, Wenqin Tang, Ziyi Zhao, Ran Zhao, Zhenyu Lv, Xuzhen Guo, Quanchang Gu, Boxiang Liu, Haoyu Lv, Jiayan Chen, Kaiquan Zhang, Fahui Li, Jiangyun Wang   +12 more
doaj   +1 more source

Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

Frontiers in Immunology, 2017
Macrophage M1/M2 polarization mediates tissue damage and inflammatory responses. Cannabinoid receptor (CB) 1 participated in liver fibrogenesis by affecting bone marrow (BM)-derived monocytes/macrophages (BMMs) activation.
Lei Tian, Weiyang Li, Le Yang, Na Chang, Xiaoting Fan, Xiaofang Ji, Jieshi Xie, Lin Yang, Liying Li   +8 more
doaj   +1 more source

Trick or Treat: Unintentional Cannabis Intoxication From Edibles in a Preschool Child—A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Case report on a 5‐year‐old female patient presenting with various organic symptoms after consumption of tetrahydrocannabinol (THC)‐containing gummy bears. Icons provided by Servier Medical Art (https://smart.servier.com/), licensed under CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/).
Eileen Heiler, Saskia Wedegärtner, Dennis Nordhoff, Eckard Hamelmann, Janina Soler Wenglein   +4 more
wiley   +1 more source

Cannabinoid type-1 receptor signaling in dopaminergic Engrailed-1 expressing neurons modulates motivation and depressive-like behavior

Frontiers in Molecular Neuroscience
The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is reported to modulate the release of several neurotransmitters, consequently affecting the activity of neuronal circuits.
Sarah Baddenhausen, Beat Lutz, Beat Lutz, Clementine Hofmann, Clementine Hofmann   +4 more
doaj   +1 more source