Results 121 to 130 of about 562,936 (248)
Journal of Neuroscience, 2004 Inhibition of primary afferent neurons contributes to the antihyperalgesic effects of opioid and CB1 receptor agonists. Two bioassays were used to compare the effects of the CB1 receptor agonist CP 55,940 and morphine on dissociated adult rat DRG neurons.
I. Khasabova +3 more
semanticscholar +1 more source
UK Medical Cannabis Registry: A Clinical Outcomes Analysis for Autism Spectrum Disorder
Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.A case series studying outcomes up to 18 months in autistic patients from the UK Medical Cannabis Registry. ABSTRACT Introduction Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with distressed behaviors and psychological challenges.
Arushika Aggarwal +17 more
wiley +1 more source
Controlled-Deactivation CB1 Receptor Ligands as a Novel Strategy to Lower Intraocular Pressure
Pharmaceuticals, 2018 Nearly half a century has passed since the demonstration that cannabis and its chief psychoactive component Δ9-THC lowers intraocular pressure (IOP).
Sally Miller +6 more
doaj +1 more source
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.Abstract Cannabinoid products are increasingly used worldwide despite limited psychiatric evidence. This narrative review synthesizes preclinical and clinical evidence on cannabidiol (CBD), cannabinol (CBN), and tetrahydrocannabinol (THC) to clarify their distinct psychiatric profiles and discuss how current evidence may inform ongoing clinical and ...
Yasuhiro Kishi +2 more
wiley +1 more source
Untersuchungen zur Rolle des endogenen Cannabinoidsystems bei der Anpassung an aversive Situationen [PDF]
, 2006 Ziel der vorliegenden Arbeit war es zu untersuchen, auf welche Art und Weise das endogene Cannabinoidsystem die Extinktion konditionierter Furcht vermittelt. Dabei gliedert sich diese Arbeit in vier Teile.
Kamprath, Kornelia
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues +8 more
wiley +1 more source
A lesão dopaminérgica como modelo de estágio pré-motor da doença de Parkinson: efeitos do antagonismo do receptor CB1 [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010Além dos sinais motores clássicos, a doença de Parkinson é caracterizada por déficits cognitivos e ...
Tadaiesky, Meigy Tavares
core
Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7768-7778, September 2026.ABSTRACT Background The obesity pharmacotherapy landscape is evolving rapidly, with several approved incretin‐based therapies and an expanding pipeline of investigational compounds targeting multiple metabolic pathways. Conventional evidence syntheses often struggle to accommodate differences in dose selection, treatment duration and stage of clinical ...
Matteo Monami +2 more
wiley +1 more source
Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]
, 2013 BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Walters, JA +5 more
core +1 more source
CUMYL-4CN-BINACA Is an Efficacious and Potent Pro-Convulsant Synthetic Cannabinoid Receptor Agonist
Frontiers in Pharmacology, 2019 Synthetic cannabinoid receptor agonists (SCRAs) are the largest class of new psychoactive substances (NPS). New examples are detected constantly, and some are associated with a series of adverse effects, including seizures.
Richard C. Kevin +15 more
doaj +1 more source