Results 221 to 230 of about 129,465 (297)

Chemokines and their receptors in oral squamous cell carcinoma: mechanisms, clinical significance, and therapeutic implications. [PDF]

Front Immunol
Li D, Chen S, Ji J, Wang Z, Zhou H, Liao Z, Tang Q.   +6 more
europepmc   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

CCR-CCL axes as key upstream influencers of pancreatic ductal adenocarcinoma: CCR2-CCL2, CCR5-CCL5, CCR4-CCL17/22, CCR6-CCL20, CCR7-CCL19/21. [PDF]

Front Immunol
Bahng I.
europepmc   +1 more source

Coacervate‐Mediated Lysosome‐Targeting Antibody Delivery for Protein Degradation

Advanced Science, EarlyView.
Targeting coacervates to the lysosome in the cytoplasm is a challenge. Here, we convert a tetrapeptide into lysosome‐targeting, membrane‐translocating coacervates. The lysosome‐sorting peptide coacervates facilitate coacervate‐mediated delivery of antibody antigen complexes and a PROTAC compound to the lysosome for the targeted degradation of cancer ...
Dingdong Yuan, Yishu Bao, Zhiyi Xu, Zhong Zheng, Yongxu Han, Kai Cheng, Yuan‐Di Zhao, Jiang Xia   +7 more
wiley   +1 more source

Olaparib, durvalumab, and cyclophosphamide, and a prognostic blood signature in platinum-sensitive ovarian cancer: the randomized phase 2 SOLACE2 trial. [PDF]

Nat Commun
Lee CK, Kartikasari AER, Bound NT, Francis KE, Shield-Artin K, Bedo J, Nesic K, Diamante K, O'Connell RL, Madondo M, Cox M, Davies C, Deceneux C, Goodchild G, Jarratt A, Cassar E, Amer H, Kariyawasam UGIU, Lee YC, Lombard J, Baron-Hay S, Antill Y, Shannon C, Selva-Nayagam S, Beale P, Zebic D, Simon S, Linaker A, Quinn MA, Papenfuss AT, Wakefield MJ, Vandenberg CJ, Friedlander M, Scott CL, Plebanski M.   +34 more
europepmc   +1 more source

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao, Chuyu Yun, Hongying Shan, Yuqian Wang, Xiunan Chen, Weisi Lian, Tianliu Peng, Min Zhao, Xunsi Qin, Kailun Hu, Ping Zhou, Yue Wang, Yanli Pang, Rong Li   +13 more
wiley   +1 more source

Human and viral chemokines differentially modulate G protein signaling, β-arrestin recruitment and chemotaxis mediated by the viral G protein-coupled receptor ORF74. [PDF]

Cell Commun Signal
Kong Q, Van Bosstraeten B, Jacquemyn M, Daelemans D, De Jonghe S, Schols D, Van Loy T.   +6 more
europepmc   +1 more source

Neuroinflammatory and transcriptional dynamics during SARS-CoV-2 infection in KRT18-hACE2 mouse brain. [PDF]

Front Immunol
Ahn DG, Mai NTQ, Jeong DJ, Moon BS.
europepmc   +1 more source

Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]

Mediators Inflamm
Farahani H, Kokhaei P, Ganji A, Mosayebi G, Ghazavi A.   +4 more
europepmc   +1 more source

Unraveling the anti-inflammatory effects of Mediterranean diet in patients with cancer remission. [PDF]

Front Immunol
Di Tolla MF, Libutti M, D'Onofrio G, Riccio A, Cabaro S, Longo M, Parascandolo A, Ferraro G, Formisano E, D'Esposito V, Formisano P.   +10 more
europepmc   +1 more source