Results 81 to 90 of about 216,047 (309)

Genetic tumor syndromes in female cancer: insights into inherited cancer predisposition and clinical implications

Archives of Gynecology and Obstetrics
A relevant proportion of malignancies predominantly or exclusively affecting women, including breast and gynecologic cancers, is attributable to hereditary tumor syndromes, profoundly impacting cancer risk, prognosis, and therapeutic management.
Annika Krückel, Julia Gocke, Manuel Hörner, Katharina Keller, Carolin Müller, Lena Brückner, Felix Heindl, Carolin C. Hack, Matthias W. Beckmann, Niklas Amann   +9 more
doaj   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Spin‐Selective Oxygen Evolution in Chiral Molecule‐Intercalated Layered Double Hydroxides

Advanced Science, EarlyView.
This hybrid electrocatalyst utilizes chiral phenylalanine intercalation within layered double hydroxides to boost oxygen evolution. Acting as a spin filter via the chiral‐induced spin selectivity effect, the material directs electron transfer along a lower‐energy pathway.
Chih‐Ying Huang, Cheng‐Rong Wu, Yang‐Sheng Lu, Yu‐Ying Chang, Chia‐Che Chang, Tsung‐Hsin Liu, Che‐Lun Lee, Jessie Shiue, Yu‐Chang Lin, Wei‐Tsung Chuang, Huang‐Ming Tsai, Ya‐Lun Ho, Jau‐Wern Chiou, Hua‐Shu Hsu, Shao‐Sian Li, Chia‐Chun Chen, Way‐Faung Pong, Chun‐Wei Chen   +17 more
wiley   +1 more source

Modeling hospital catchment areas in pediatric oncology using an empirically parameterized extended Huff-model

International Journal of Health Geographics
Background Specialized pediatric oncology is typically concentrated in a few high-volume centers, creating tensions between the need for centralization and equitable spatial access.
Jonas Kapitza, Thomas Wieland, Markus Metzler   +2 more
doaj   +1 more source

Place of Death of Cancer Patients Treated at a German Comprehensive Cancer Center

Palliative Medicine Reports
Background: Public health research includes end-of-life care. Place of death is an indicator of end-of-life care quality. Objective: We assessed the place of death of cancer patients treated at a Comprehensive Cancer Center (CCC), caring for an average ...
Julia Berendt, Maria Heckel, Christoph Ostgathe, Stephanie Stiel, Peter Stachura, Andreas Becker, Matthias W. Beckmann, Susanne Gahr   +7 more
doaj   +1 more source

Impact of Coronary Collateral Circulation on In-Hospital Death in Patients with Inferior ST Elevation Myocardial Infarction

Cardiology Research and Practice, 2015
Objectives. Coronary collateral circulation (CCC) may limit the size of right ventricular (RV) infarcts but does not fully explain the relationship between CCC and clinical adverse events in patients with inferior STEMI.
Baris Yaylak, Bernas Altintas, Huseyin Ede, Erkan Baysal, Sukru Akyuz, Onder Bilge, Utkan Sevuk, Guney Erdogan, Haci Ciftci   +8 more
doaj   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Experiments with CCC on wheat: effects of spacing, nitrogen and irrigation

, 1969
In experiments with spring and winter wheat at Rothamsted and Woburn during 4 years CCC increased yield at close spacing (4 in) (10 cm) more than at usual spacing (8 in) (20 cm), but there was no interaction between spacing and yield.
Bond, W., Humphries, E. C.
core   +1 more source

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Opus CCC

, 1955
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources