Results 51 to 60 of about 11,820 (181)

Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population

Journal of Neuroinflammation, 2012
Background Inflammatory mechanisms are important in stroke risk, and genetic variations in components of the inflammatory response have been implicated as risk factors for stroke.
Zhao Nan, Liu Xin, Wang Yongqin, Liu Xiaoqiu, Li Jiana, Yu Litian, Ma Liyuan, Wang Shuyu, Zhang Hongye, Liu Lisheng, Zhao Jingbo, Wang Xingyu   +11 more
doaj   +1 more source

Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease

Scientific Reports, 2023
Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single nucleotide polymorphisms (SNP) of chemokine in AITD patients compared to normal controls.
Chungwoo Shin, In-Cheol Baek, Won Kyoung Cho, Tai-Gyu Kim, Byung-Kyu Suh   +4 more
doaj   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

CCL11 (Eotaxin) Induces CCR3-Dependent Smooth Muscle Cell Migration [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
Objective— CCL11 (Eotaxin) is a potent eosinophil chemoattractant that is abundant in atheromatous plaques. The major receptor for CCL11 is CCR3, which is found on leukocytes and on some nonleukocytic cells. We sought to determine whether vascular smooth muscle cells (SMCs) possessed functional CCR3.
Ravindra B, Kodali, William J H, Kim, Irfan I, Galaria, Christine, Miller, Alison D, Schecter, Sergio A, Lira, Mark B, Taubman   +6 more
openaire   +2 more sources

The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells [PDF]

Allergy, 2008
Background:  Airway smooth muscle hyperplasia is a feature of asthma, and increases with disease severity. CCR3‐mediated recruitment of airway smooth muscle progenitors towards the airway smooth muscle bundle has been proposed as one possible mechanism involved in airway smooth muscle hyperplasia.
Saunders, R, Sutcliffe, A, Woodman, L, Kaur, D, Siddiqui, S, Okayama, Y, Wardlaw, A, Bradding, P, Brightling, C   +8 more
openaire   +3 more sources

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda, Yohei Sato, Yoshimasa Imoto, Mayumi Tamari, Shigeharu Fujieda   +4 more
wiley   +1 more source

Serum C-C motif ligand 11/Eotaxin-1 may serve as a candidate biomarker for postmenopausal osteoporosis [PDF]

Journal of Medical Biochemistry, 2019
Background: The chemokine C-C motif ligand 11, also known as eotaxin-1, has been identified as a novel mediator of inflammatory bone resorption. However, little is known regarding a potential role for CCL11/Eotaxin-1 in postmenopausal osteoporosis ...
Wang Wen, Huang Ci-You, Wang Zhuo-Ping, Xu Shan-Shan, Qian Tie-Yong, Chen Yi-Ding, Wu Wei-Guo   +6 more
doaj  

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis [PDF]

Journal of Leukocyte Biology, 2013
ABSTRACTThis study tested the hypothesis that eotaxins (CCL11, CCL24, and CCL26) and IL-5 contribute to eosinophil recruitment to the intestine in UC and that intestinal macrophages are important producers of CCL11 in this disease. Peripheral blood and rectal biopsy samples were obtained from patients with active (n=18) and quiescent UC (n=9), and ...
Maria, Lampinen, Amanda, Waddell, Richard, Ahrens, Marie, Carlson, Simon P, Hogan   +4 more
openaire   +2 more sources

Elevated Plasma Chemokines for Eosinophils in Neuromyelitis Optica Spectrum Disorders during Remission

Frontiers in Neurology, 2018
BackgroundA prominent pathological feature of neuromyelitis optica spectrum disorders (NMOSD) is markedly greater eosinophilic infiltration than that seen in other demyelinating diseases, like multiple sclerosis (MS).
Yanping Tong, Yanping Tong, Tao Yang, Tao Yang, Jingwen Wang, Tianyou Zhao, Lei Wang, Yuezhi Kang, Cuicui Cheng, Yongping Fan, Yongping Fan   +10 more
doaj   +1 more source