SNPs in inflammatory genes CCL11, CCL4 and MEFV in a fibromyalgia family study.
PLoS ONE, 2018 BackgroundFibromyalgia (FM) is a chronic pain syndrome with a high incidence in females that may involve activation of the immune system. We performed exome sequencing on chemokine genes in a region of chromosome 17 identified in a genome-wide family ...
Zhifang Zhang +10 more
doaj +3 more sources
Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement [PDF]
Translational PsychiatryPostpartum depression (PPD) is linked to neuroimmune dysregulation. Brexanolone, an intravenous formulation of the neurosteroid allopregnanolone and the first FDA-approved treatment for PPD, produces rapid and sustained antidepressant effects.
Irina Balan +7 more
doaj +2 more sources
Frontiers in Immunology, 2015 The eosinophil was first named by the brilliant German scientist Paul Ehrlich in 1879, while he was experimenting with aniline dyes to stain blood cells and tissues. He also discovered neutrophils, basophils, and mast cells. The highly basic proteins in cytosolic granules of a small subpopulation of cells in human blood stained vivid pink with the acid
TIMOTHY JOHN WILLIAMS
doaj +4 more sources
Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling [PDF]
Immunity & AgeingBackground The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective
Sheng Tian +7 more
doaj +2 more sources
Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis
Iranian Journal of Public Health, 2020 Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI +6 more
doaj +4 more sources
Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis
BiomedicinesObjective: The course of relapsing–remitting multiple sclerosis (RRMS) is highly variable and there is a lack of effective prognostic biomarkers. This study aimed to assess the potential prognostic value of the chemokines B lymphocyte chemoattractant ...
Işıl Peker +9 more
doaj +3 more sources
Effect of CCL11 on In Vitro Myogenesis and Its Clinical Relevance for Sarcopenia in Older Adults [PDF]
Endocrinology and Metabolism, 2021 Background The C-C motif chemokine ligand 11 (CCL11) has been receiving attention as a potential pro-aging factor. Accordingly, it may be involved in muscle metabolism and sarcopenia, a key component of aging phenotypes.
Da Ae Kim +9 more
doaj +1 more source
Eotaxin/CCL11 in idiopathic retroperitoneal fibrosis [PDF]
Nephrology Dialysis Transplantation, 2012 Idiopathic retroperitoneal fibrosis (IRF) is a rare fibro-inflammatory disorder characterized by a periaortic tissue which often encases the ureters causing acute renal failure. IRF histology shows fibrosis and a chronic inflammatory infiltrate with frequent tissue eosinophilia.
Mangieri D +12 more
openaire +6 more sources
IL-9 induces CCL11 expression via STAT3 signalling in human airway smooth muscle cells. [PDF]
PLoS ONE, 2010 Previous findings support the concept that IL-9 may play a significant role in mediating both pro-inflammatory and changes in airway responsiveness that characterizes the atopic asthmatic state. We previously demonstrated that human airway smooth muscle (
Akira Yamasaki +5 more
doaj +1 more source
CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age
Cells, 2019 CCL11 has recently been shown to differentially affect cell survival under various pathological conditions including stroke. Indeed, CCL11 promotes neuroregeneration in neonatal stroke mice.
Simone Lieschke +10 more
doaj +1 more source