Results 221 to 230 of about 86,321 (247)

Nitration of CCL2 disrupts the tumor-protective function of CCL2 in bladder cancer

The Journal of Immunology, 2022
Abstract The chemokine CCL2 (C-C motif ligand 2) is best known for its ability to induce trafficking of immune cells by binding its primary receptor, CCR2. The recruitment of immunosuppressive monocytes by CCL2 promotes cancer in several tumor types. Surprisingly, we previously found an unanticipated protective role for CCL2 signaling in
Neelam Mukherjee, Niannian Ji, Zhen-Ju Shu, Tyler J Curiel, Robert S Svatek   +4 more
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ChemInform Abstract: Fluorination with Concomitant Cyclization of CCl2=N‐CCl2‐CCl2‐N=CCl2 with SbF5 and Molecular Structure of a 2‐Imidazolidinone Derivative.

ChemInform, 1987
AbstractFluorination of the perchlorodiazahexadiene (I) yields the imidazolines (III) or (IV), depending on the amount of the fluorinating agent SbF5 (II) used.
G. PAWELKE, H. + BUERGER, D. J. BRAUER, J. WILKE   +3 more
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Ccl2 Determinations

Journal AWWA, 2008
On July 30, 2008, the U.S. Environmental Protection Agency (USEPA) finalized the regulatory determinations for 11 contaminants on the Second Contaminant Candidate List (CCL2). Considering the best available data, USEPA concluded that these contaminants occur infrequently at levels of public health concern in public water systems.
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Hyperocclusion Stimulates Osteoclastogenesis via CCL2 Expression

Journal of Dental Research, 2011
Excessive mechanical stress (MS) during hyperocclusion is known to result in disappearance of the alveolar hard line, enlargement of the periodontal ligament (PDL) space, and destruction of alveolar bone, leading to occlusal traumatism. We hypothesized that MS induces expression of osteoclastogenesis-associated chemokines in PDL tissue, resulting in ...
K T, Goto, H, Kajiya, T, Nemoto, T, Tsutsumi, T, Tsuzuki, H, Sato, K, Okabe   +6 more
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CCL2 (monocyte chemoattractant protein-1) and cancer

Seminars in Cancer Biology, 2004
Genetic analyses of cancer in humans indicate that chemokines and their receptors are unlikely to play direct roles in pathogenesis. However, these molecules have pleiotropic effects that impact on cancer pathobiology in animal models, and there is evidence that they may do the same in humans. Given their protean properties, chemokines could have tumor-
Ilaria, Conti, Barrett J, Rollins
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Synthesis of aromatic compounds of types ArCH2CH = CCl2 and Ar?(CH2CH = CCl2)2

Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1959
1. The condensation of 1,1,3-trichloro-1-propene with benzene, toluene, 3-phenyl-1,1-dichloro-1-propene, 3-(p-chlorophenyl)-1,1-dichloro-1-propene, naphthalene and 3-phenyl-1,1,1,2-tetrachloropropane was carried out in the presence of aluminum chloride or antimony pentachloride, with the formation of the corresponding mono- and di-alkylated products.
R. Kh. Freidlina, N. A. Semenov, A. N. Nesmeyanov   +2 more
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Kinetics of the CCl2+ Br2 and CCl2+ NO2 reactions in the temperature range 266−365 K and reactivity of the CCl2 biradical

Chemical Physics Letters, 2008
Abstract The kinetics of the CCl2 + Br2 and CCl2 + NO2 reactions have been studied at temperatures between 266 and 365 K using laser photolysis/photoionization mass spectrometry. Dichloromethylene biradicals were produced by the pulsed laser photolysis of CCl4.
Arkke J. Eskola, Iwona Golonka, Matti P. Rissanen, Raimo S. Timonen   +3 more
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TRPV1 receptor inhibition decreases CCL2-induced hyperalgesia

Neuropharmacology, 2014
Modulation of nociceptive synaptic transmission in the spinal cord is implicated in the development and maintenance of several pathological pain states. The chemokine CCL2 (C-C motif ligand 2) was shown to be an important factor in the development of neuropathic pain after peripheral nerve injury.
Diana, Spicarova, Pavel, Adamek, Nataliia, Kalynovska, Petra, Mrozkova, Jiri, Palecek   +4 more
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Stimulation of CCL2 (MCP-1) and CCL2 mRNA by substance P in LAD2 human mast cells

Translational Research, 2009
Chemokines are cytokines with chemotactic properties on inflammatory cells and other cell types. Chemokine (C-C motif) ligand 2 (CCL2), which is also called monocyte chemotactic protein 1 (MCP-1), is a potent chemotactic molecule that attracts lymphocytes, monocytes, mast cells, and memory T cells, but not neutrophils.
Castellani ML, VECCHIET, Jacopo, SALINI, VINCENZO, Conti P, Theoharides TC, Caraffa A, Antinolfi P, TETE', Stefano, Ciampoli C, CUCCURULLO, CHIARA, Cerulli G, FELACO, Mario, BOSCOLO, Paolo   +12 more
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CCL2/CCR2 signaling pathway in glioblastoma multiforme

Neurochemistry International, 2017
Glioblastoma multiform (GBM) is described as one of the most frequent primary brain tumors. These types of malignancies constitute only 15% of all primary brain tumors. Despite, extensive developments on effective therapeutic methods during the 20th century as well as the first decade of the present century (21st), the median survival rate for patients
Alireza, Vakilian, Hossein, Khorramdelazad, Parisa, Heidari, Zahra, Sheikh Rezaei, Gholamhossein, Hassanshahi   +4 more
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