Results 51 to 60 of about 106,788 (300)
Plasma Chemokine C-C Motif Ligand 2 as a Potential Biomarker for Prostate Cancer
Martin Lund,1 Torben B Pedersen,1 Søren Feddersen,2,3 Louise D Østergaard,1,3 Charlotte A Poulsen,1 Christian Enggaard,2 Mads HA Poulsen,1,3 Lars Lund1,3 1Department of Urology, Odense University Hospital, Odense, Denmark; 2Department of Clinical ...
Lund M +7 more
doaj
Phenotyping CCL2 Containing Central Amygdala Neurons Controlling Alcohol Withdrawal-Induced Anxiety
Chemokines such as chemokine (C-C motif) ligand 2 (CCL2) play a role in several behaviors, including anxiety-like behavior, but whether neurons are an important source of CCL2 for behavior and how neuronal CCL2 may work to affect behavior are still ...
Kathryn M. Harper +12 more
doaj +1 more source
Introduction: In this study, the role of transcription factor Forkhead/winged helix box protein O3a (FoxO3a) in Cyr61 expression and its modulation by simvastatin were investigated in cultured murine osteoblasts and a rat model of induced apical ...
王若松;林思洸;林立德;洪志遠;郭生興;賴向華;楊湘;李明澍 +1 more
core +1 more source
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu +14 more
wiley +1 more source
Introduction & Objective: Age-related macular degeneration (AMD) is a disease affecting the central regions of the retina and choroid, which can lead to loss of central vision.
Tahereh Mohammadian +3 more
doaj
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation
Novel minimally invasive strategies are needed to obtain robust bone healing in complex fractures and bone defects in the elderly population. Local cell therapy is one potential option for future treatment.
Masakazu Toya +9 more
doaj +1 more source
CCL2 rs1024611Gene Polymorphism in Philadelphia-Negative Myeloproliferative Neoplasms
Introduction: The onset of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is caused by acquired somatic mutations in target myeloid genes “driver mutations”.
Abdallah Ahmed Elsawy +6 more
core +1 more source
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira +8 more
wiley +1 more source
The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts. [PDF]
Chemokine ligand 2 (CCL2), also known as monocyte chemoattractant protein-1 (MCP-1), belongs to the CC chemokine family that is associated with the disease status and outcomes of osteoarthritis (OA).
Yu-Min Lin +4 more
doaj +1 more source
CCL2-mCherry has similar potency as wild type CCL2.
Freshly isolated human monocytes chemotaxis was measured in Boyden chamber chemotaxis assays at the indicated concentrations (A). Wild type CCL2 (black circles) and CCL2-mCherry (red circles) was added to the lower compartment at the indicated ...
Elisabetta Cameroni (164313) +5 more
core +1 more source

