Results 51 to 60 of about 100,029 (302)
Phenotyping CCL2 Containing Central Amygdala Neurons Controlling Alcohol Withdrawal-Induced Anxiety
Frontiers in Cellular Neuroscience, 2020 Chemokines such as chemokine (C-C motif) ligand 2 (CCL2) play a role in several behaviors, including anxiety-like behavior, but whether neurons are an important source of CCL2 for behavior and how neuronal CCL2 may work to affect behavior are still ...
Kathryn M. Harper +12 more
doaj +1 more source
Beneficial impact of CCL2 and CCL12 neutralization on experimental malignant pleural effusion. [PDF]
PLoS ONE, 2013 Using genetic interventions, we previously determined that C-C motif chemokine ligand 2 (CCL2) promotes malignant pleural effusion (MPE) formation in mice.
Antonia Marazioti +10 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
CCL2-mCherry has similar potency as wild type CCL2.
, 2012 Freshly isolated human monocytes chemotaxis was measured in Boyden chamber chemotaxis assays at the indicated concentrations (A). Wild type CCL2 (black circles) and CCL2-mCherry (red circles) was added to the lower compartment at the indicated ...
Elisabetta Cameroni (164313) +5 more
core +1 more source
Immune molecule diagnostics in colorectal cancer: CCL2 and CXCL11
Open Life SciencesTraditional serrated adenomas (TSAs) and sessile serrated adenomas (SSAs) are known precursors to colorectal cancer (CRC), but differentiating between them morphologically can be challenging.
Zhang Hui +4 more
doaj +1 more source
MicroRNA-33 suppresses CCL2 expression in chondrocytes [PDF]
Bioscience Reports, 2016 CCL2-mediated macrophage infiltration in articular tissues plays a pivotal role in the development of the osteoarthritis (OA). miRNAs regulate the onset and progression of diseases via controlling the expression of a series of genes. How the CCL2 gene was regulated by miRNAs was still not fully elucidated. In the present study, we demonstrated that the
Wei, Meng +9 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Analysis of CCL2 expression in embryonic tissues.
, 2019 A) Flow cytometric analysis of E12.5 total YS cells from CCL2-reporter mice showing i) a discrete CCL2-expressing population and ii) CD11b and F4/80 gating, demonstrating that this population is largely CD11bhiF4/80lo.
Kit Ming Lee (6751391) +7 more
core +1 more source