Results 51 to 60 of about 106,788 (300)

Plasma Chemokine C-C Motif Ligand 2 as a Potential Biomarker for Prostate Cancer

open access: yesResearch and Reports in Urology, 2022
Martin Lund,1 Torben B Pedersen,1 Søren Feddersen,2,3 Louise D Østergaard,1,3 Charlotte A Poulsen,1 Christian Enggaard,2 Mads HA Poulsen,1,3 Lars Lund1,3 1Department of Urology, Odense University Hospital, Odense, Denmark; 2Department of Clinical ...
Lund M   +7 more
doaj  

Phenotyping CCL2 Containing Central Amygdala Neurons Controlling Alcohol Withdrawal-Induced Anxiety

open access: yesFrontiers in Cellular Neuroscience, 2020
Chemokines such as chemokine (C-C motif) ligand 2 (CCL2) play a role in several behaviors, including anxiety-like behavior, but whether neurons are an important source of CCL2 for behavior and how neuronal CCL2 may work to affect behavior are still ...
Kathryn M. Harper   +12 more
doaj   +1 more source

Simvastatin Suppresses Osteoblastic Expression of Cyr61 and Progression of Apical Periodontitis through Enhancement of the Transcription Factor Forkhead/Winged Helix Box Protein O3a

open access: yes, 2014
Introduction: In this study, the role of transcription factor Forkhead/winged helix box protein O3a (FoxO3a) in Cyr61 expression and its modulation by simvastatin were investigated in cultured murine osteoblasts and a rat model of induced apical ...
王若松;林思洸;林立德;洪志遠;郭生興;賴向華;楊湘;李明澍   +1 more
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

Study of C-2518T Polymorphism of CCL2 Gene in Age Related Macular Degeneration Patients from Northwest of Iran

open access: yesپزشکی بالینی ابن سینا, 2015
Introduction & Objective: Age-related macular degeneration (AMD) is a disease affecting the central regions of the retina and choroid, which can lead to loss of central vision.
Tahereh Mohammadian   +3 more
doaj  

CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation

open access: yesFrontiers in Cell and Developmental Biology, 2023
Novel minimally invasive strategies are needed to obtain robust bone healing in complex fractures and bone defects in the elderly population. Local cell therapy is one potential option for future treatment.
Masakazu Toya   +9 more
doaj   +1 more source

CCL2 rs1024611Gene Polymorphism in Philadelphia-Negative Myeloproliferative Neoplasms

open access: yes, 2022
Introduction: The onset of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) is caused by acquired somatic mutations in target myeloid genes “driver mutations”.
Abdallah Ahmed Elsawy   +6 more
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

The CCL2/CCR2 axis enhances vascular cell adhesion molecule-1 expression in human synovial fibroblasts. [PDF]

open access: yesPLoS ONE, 2012
Chemokine ligand 2 (CCL2), also known as monocyte chemoattractant protein-1 (MCP-1), belongs to the CC chemokine family that is associated with the disease status and outcomes of osteoarthritis (OA).
Yu-Min Lin   +4 more
doaj   +1 more source

CCL2-mCherry has similar potency as wild type CCL2.

open access: yes, 2012
Freshly isolated human monocytes chemotaxis was measured in Boyden chamber chemotaxis assays at the indicated concentrations (A). Wild type CCL2 (black circles) and CCL2-mCherry (red circles) was added to the lower compartment at the indicated ...
Elisabetta Cameroni (164313)   +5 more
core   +1 more source

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