Results 211 to 220 of about 94,786 (284)

Analysis of MSX1, RYK, NFκB p65, and CCL4 Proteins and <i>MSX2</i>, <i>RYK</i>, and <i>PTX3</i> Genes in Human Cleft Lip Tissue. [PDF]

Int J Mol Sci
Vaivads M, Rone AE, Pilmane M.
europepmc   +1 more source

Timing of Glucocorticoid Treatment Dictates Glucocorticoid Receptor Actions Modulating the NLRP3‐Inflammasome Activation in Macrophages

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Utilizing a clinically relevant course of treatment, our study reveals that glucocorticoids protect against the late NLRP3 inflammasome activation regulating the IL‐1β secretion, the processing of GSDM‐D and pyroptosis following signal 2 stimulation. These potent anti‐inflammatory effects are mediated by the activation of GR signaling and the expansion
David Diaz‐Jimenez, Robert H. Oakley, Jackson A. Hoffman, Carl D. Bortner, Fred Lih, Jianying Li, Jason G. Williams, Erica Scappini, Kevin E. Gerrish, Stavros Garantziotis, Trevor K. Archer, John A. Cidlowski   +11 more
wiley   +1 more source

Five-year clinical outcome and immune biomarkers of durable response from the MM1636 trial on IDO/PD-L1 vaccination and PD-1 blockade in first line metastatic melanoma. [PDF]

Nat Commun
Pedersen S, Byrdal M, Martinenaite E, Lorentzen CL, Kjeldsen JW, Thorsen SU, Kverneland A, Zocca MB, Andersen MH, Svane IM.   +9 more
europepmc   +1 more source

North Atlantic 2001 - Part 1 Cruise No. 50, Leg 1 7 May – 31 May 2001, Halifax – St. John’s [PDF]

, 2002
Begler, Christian, Brandt, Peter, Coenen, A., Dombrowsky, Uwe, Fischer, Jürgen, Friis, Karsten, Getzlaff, Klaus, Jancke, K., Johannsen, Hergen, Kahl, G., Kieke, Dagmar, Lübs, H., Lüger, Heike, Müller, Mario, Ochsenhirt, W.-T., Papenburg, Uwe, Schmidt, Hauke, Schütt, Martina, Steinhoff, Tobias, Stramma, Lothar, Stransky, Julia, Streu, Peter   +21 more
core  

Serum cytokines predict response and survival in esophageal squamous cell carcinoma receiving chemoradiotherapy combined with anti-PD-1 antibody: analyses of two phase II clinical trials. [PDF]

J Immunother Cancer
Chen B, Chen J, Wang S, Bai K, Li Z, Chen B, Wang R, Cheng X, Gao Y, Yi C, Cen P, Li S, Dragomir MP, Zhu Y, Li Q, Yang H, Xi M.   +16 more
europepmc   +1 more source

YAP contributes to liver injury through mediating capillarization of liver sinusoidal endothelial cells via GATA6/eNOS signaling. [PDF]

Cell Mol Biol Lett
Wang J, Shen Z, Chen G, Dai W, Mei Z, Shen B, Guo Y, Wang J, Zhangdi H, Zhang Q, Gao J, Ge Q, Zhou H, Dong H, Lu L, Cai X.   +15 more
europepmc   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Acetyl-CoA acyltransferase 2 palmitoylation drives liver fibrosis by inducing hepatic stellate cell ferroptosis. [PDF]

Redox Biol
Han J, Yan Z, Sun Z, Dang W, Li B, Li S, Lv X, Ni L, He A, Gu P, Wang F, Wang L, Yang X.   +12 more
europepmc   +1 more source

NH3‐Guided Low‐Temperature Nanostructural Refinement Boosts Visible‐Light‐Driven H2O2 Synthesis in Ionic Carbon Nitrides

Advanced Materials, Volume 38, Issue 7, 2 February 2026.
A nanostructural refinement strategy is reported for KPHI photocatalysts using NH4Cl in a molten salt environment to induce coherent domain fragmentation and controlled cyano defect formation. This dual modification promotes n→π* transitions, enhances charge separation, and accelerates ORR kinetics, yielding exceptional AQY values of 49% (410 nm) and 5%
Jaya Bharti, Jokotadeola Odutola, Zahra Hajiahmadi, Karlo Nolkemper, Zhihong Tian, Haijian Tong, Vitaliy Shvalagin, Thomas D. Kühne, Tero‐Petri Ruoko, Christian Mark Pelicano   +9 more
wiley   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source