Results 161 to 170 of about 50,982 (245)

Cytokines IL-6, IL-10, and CCL5 Secreted by Infiltrating B Cells Promote Cell Migration of Human Prostate Cancer Cell Lines. [PDF]

Oncol Res
Byrd CJ, Evans M, Kim W, Knight Q, Liou GY.   +4 more
europepmc   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, EarlyView.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Donor macrophage depletion permits posttransplant tolerance induction in a murine islet transplant model. [PDF]

Am J Transplant
Dilts M, Fay OK, Yu Y, Jordan CZ, Luo X.
europepmc   +1 more source

Structural insights into tyrosine sulfation of CCR5 by human tyrosylprotein sulfotransferase‐1

The FEBS Journal, EarlyView.
Structural analysis of human tyrosylprotein sulfotransferase‐1 (hTPST1) bound to a CCR5 N‐terminal peptide reveals how hTPST1 recognizes the Tyr3 sulfation site. Structure‐guided models of additional CCR5 sulfation states and full‐length assemblies provide a framework for understanding CCR5 tyrosine sulfation, a post‐translational modification relevant
Shinnosuke Tanaka, Hirai Asano, Kota Toyoda, Toshiaki Nishiyori, Hidetaka Kojo, Kazuto Kiyomatsu, Katsuhisa Kurogi, Yoichi Sakakibara, Etsuko Nishimoto, Takamasa Teramoto, Yoshimitsu Kakuta   +10 more
wiley   +1 more source

Cinobufotalin reduces glioblastoma resistance to temozolomide by inhibiting the CCL5-mediated PI3K/Akt/mTOR signaling pathway. [PDF]

Transl Cancer Res
Sun J, Ma X, Song J, Zhang Y, Li N, Li Y, Zhang X, Han Y.   +7 more
europepmc   +1 more source

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, EarlyView.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Systemic lupus erythematosus extends beyond a type I interferonopathy, as demonstrated by NET-activated monocytes. [PDF]

Clin Transl Med
Cao X, van Heusden N, Pieren DKJ, Geertsema-Hoeve BC, Kaan ED, Greve PF, Limper M, Boes M.   +7 more
europepmc   +1 more source

Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias

Journal of Periodontal Research, EarlyView.
Monocyte‐derived macrophages from successfully treated stage III periodontitis patients show a persistent skewing toward an M1‐like pro‐inflammatory phenotype across polarization conditions, suggesting that immune dysregulation may persist despite clinical periodontal stability.
Mariane Cristina Sloniak, Josiane Betim de Assis, Luciana Saraiva, Cláudio Mendes Pannuti, Ana Paula Lepique, Cristina Cunha Villar   +5 more
wiley   +1 more source

Folate promotes colorectal cancer progression by impairing CD8⁺ T cell function and recruitment via SLC19A1/p-AKT/NOTCH1 axis and CCL5 downregulation. [PDF]

J Transl Med
Qing S, Ling Y, Lai Y, Hu Y, Zhong Y, Liu Y, Liu X, Fang Y, Qian J, Deng H, Peng Y, Wu D, Shen Z.   +12 more
europepmc   +1 more source