Results 191 to 200 of about 76,869 (253)

Histone deacetylase HDAC7 restricts CD8 + T cell tumor infiltration and limits immunotherapy sensitivity in bladder cancer: reversal by pinocembrin. [PDF]

J Exp Clin Cancer Res
Lv J, Li K, Zhou J, Yu R, Lu Q, Liu B.
europepmc   +1 more source

Parthenolide Attenuates Skeletal Muscle Atrophy Through Regulation of Protein Homeostasis and Inhibition of Inflammation

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Parthenolide attenuates skeletal muscle atrophy through coordinated regulation of protein homeostasis and inflammatory signaling. It counteracts TNF‐α‐mediated inhibition of AKT signaling, thereby restoring AKT–mTOR activation to promote protein synthesis and suppress protein degradation through inhibition of the FoxO transcription factors, which ...
Yu Bai, Weiqing Li, Yahong Lu, Hehuan Lai, Lin Ye, Kechi Li, Chendi Wang, Yi Ding, Wenhao Li, Yitao Chen, Keping Gan, Zhenzhong Chen, Dengwei He   +12 more
wiley   +1 more source

Nuclear Factor I-B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription. [PDF]

Adv Sci (Weinh)
Chen Q, Rui F, Fan Z, Yang H, Geng N, Lu C, Ni W, Huan Y, Shi J, Wu C, Yin S, An W, Lu X, Zhao Q, Li J.   +14 more
europepmc   +1 more source

Exploration Novel Therapeutic Targets for Periodontitis via Stress Granules Biomarkers. [PDF]

Int Dent J
Wang Y, Yang X, Shi B, Zhu B, Zhuang H, Chen J.   +5 more
europepmc   +1 more source

CCR-CCL axes as key upstream influencers of pancreatic ductal adenocarcinoma: CCR2-CCL2, CCR5-CCL5, CCR4-CCL17/22, CCR6-CCL20, CCR7-CCL19/21. [PDF]

Front Immunol
Bahng I.
europepmc   +1 more source

Targeting IRF7 to overcome gemcitabine resistance in pancreatic ductal adenocarcinoma. [PDF]

iScience
Yang GH, Yan HQ, Lu ZY, Xu QH, Wang Z, Zhao S.   +5 more
europepmc   +1 more source

Intratumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1⁺ cDC1 infiltration and activates anti-tumor immunity. [PDF]

Nat Commun
Gorline L, do Carmo FLR, Bourdely P, Bornères J, Vaudiau N, Semervil A, Vetillard M, Coulibaly ASK, Jugniot N, Ok A, Bausart M, Fiquet O, Andrade M, Fardol D, Haddar I, Abou Nader Z, Weber J, Theobald H, Collin M, Calmette J, Anselmi G, Fico F, Ginhoux F, Majlessi L, Gautier EL, Saveanu L, Helft J, Dalod M, Dusseaux M, Di Santo JP, Hugues S, Guermonprez P.   +31 more
europepmc   +1 more source

Inhibition of RAB7 promotes CD8⁺ T cell activation via the STING/IRF1/CCL5/CXCL10 signaling axis to promote PD-1-mediated anti-lung cancer efficacy. [PDF]

Am J Cancer Res
Liu X, Jiang Z, Li R, Li J, Zhang L, Liu H.   +5 more
europepmc   +1 more source

Targeting AKR1B1 reprograms tumor-associated macrophages to enhance antitumor immunity. [PDF]

J Immunother Cancer
Liu Y, Zhou C, Tang Y, Lei H, Aihemaiti A, Liu H, Zou P, Xie J, Guo X, Xia R, Han BH, Chen H, Zhu L.   +12 more
europepmc   +1 more source

Monocytes recruitement : RANTES/CCL5 effect on endothelial cells

, 2018
L’inflammation vasculaire est caractérisée par le recrutement monocytaire qui englobe l’arrêt, l’adhérence puis la migration trans-endothéliale des monocytes à travers l’endothélium vasculaire. Ce processus nécessite une interaction entre les médiateurs inflammatoires tels que les chimiokines, les leucocytes et les cellules endothéliales.
openaire   +1 more source