Results 221 to 230 of about 50,982 (245)
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A dual role for tumor-derived chemokine RANTES (CCL5)
Immunology Letters, 2003To investigate the role of tumor-derived CCL5 (regulated upon activation, normal T cell expressed and secreted, RANTES) in tumor immunity we compared the T cell response to tumors derived from the 4T1 murine mammary carcinoma cell line that express different levels of CCL5.
Robert A Kurt
exaly +3 more sources
Human Immunology, 2017
Genetic variations in chemokine genes influence the chemoattractive properties of T cells which may be associated with outcome of infections. In present study, we have investigated the regulatory role played by In1.1T/C (rs2280789) polymorphism of CCL5 and -135G/A (rs56061981) polymorphism of CXCL10 gene on intracellular CCL5 and CXCL10 expression in T
Singh, Brijendra +2 more
openaire +3 more sources
Genetic variations in chemokine genes influence the chemoattractive properties of T cells which may be associated with outcome of infections. In present study, we have investigated the regulatory role played by In1.1T/C (rs2280789) polymorphism of CCL5 and -135G/A (rs56061981) polymorphism of CXCL10 gene on intracellular CCL5 and CXCL10 expression in T
Singh, Brijendra +2 more
openaire +3 more sources
2009
The multifaceted roles of chemokines and of their receptors in physiological and pathological conditions have motivated researchers to analyze their involvement also in malignant diseases. This chapter focuses on CCL5 (RANTES) and its CCR5 receptor in cancer, describing their expression patterns, activities, and roles in several malignancies. Thus far,
Gali Soria, Adit Ben-Baruch
openaire +1 more source
The multifaceted roles of chemokines and of their receptors in physiological and pathological conditions have motivated researchers to analyze their involvement also in malignant diseases. This chapter focuses on CCL5 (RANTES) and its CCR5 receptor in cancer, describing their expression patterns, activities, and roles in several malignancies. Thus far,
Gali Soria, Adit Ben-Baruch
openaire +1 more source
CCL5 induces a pro-inflammatory profile in microglia in vitro
Cellular Immunology, 2011The chemokine receptors CCR1, CCR2, CCR3, CCR5, and CXCR2 have been found to be expressed on microglia in many neurodegenerative diseases, such as multiple sclerosis and Alzheimer's disease. There is emerging evidence that chemokines, besides chemoattraction, might directly modulate reactive profiles of microglia.
Škuljec, Jelena +8 more
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The CCL5 in Breast Cancer is Platelet CCL5- A Hypothesis
Medicon Medical Sciences, 2022openaire +1 more source