Cerebral cavernous malformations (CCMs) are vascular lesions of the CNS characterized by abnormally enlarged capillary cavities that can occur sporadically or as a familial autosomal dominant condition with incomplete penetrance and variable clinical expression attributable to mutations in three different genes: CCM1 (Krit1), CCM2 (MGC4607) and CCM3 ...
D'ANGELO, Rosalia +7 more
openaire +4 more sources
Multilayer Core‐Shell Fiber Device for Improved Strain Sensing and Supercapacitor Applications
A unique, flexible, and durable fiber is created by the blending of materials such as carbon nanotubes, MXene, and cotton through a process known as dry spinning. Highly sensitive to small stretches and excelling in energy storage, this innovative fiber surpasses ordinary fibers. It has been shown to perform well under various environmental conditions,
Md Milon Hossain +4 more
wiley +1 more source
Defective autophagy is a key feature of cerebral cavernous malformations
Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal ...
Saverio Marchi +17 more
doaj +1 more source
A numerical and experimental investigation of the impact of wire mesh on vertical solar still
One of the most pressing challenges facing human society is the lack of freshwater, Traditional desalination is energy-intensive, posing challenges in energy-scarce regions, especially in less developed nations.
Mohammadreza Abbaspour +2 more
doaj +1 more source
CCM proteins control endothelial β1 integrin dependent response to shear stress
Hemodynamic shear stress from blood flow on the endothelium critically regulates vascular function in many physiological and pathological situations. Endothelial cells adapt to shear stress by remodeling their cytoskeletal components and subsequently by ...
Zuzana Macek Jilkova +8 more
doaj +1 more source
The subtropical global plume in the Pacific Exploratory Mission-Tropics A (PEM-Tropics A), PEM-Tropics B, and the Global Atmospheric Sampling Program (GASP): How tropical emissions affect the remote Pacific [PDF]
[1] An extended southern subtropical plume of CO meanders>15,000 km around the world, gradually spreading around 20 S. This southern pollution plume is most noticeable in the burning season, southern spring; a similar subtropical plume appears in the ...
Blake, DR +4 more
core +2 more sources
Zebrafish models of cerebrovascular disease [PDF]
Perturbations in cerebral blood flow and abnormalities in blood vessel structure are the hallmarks of cerebrovascular disease. While there are many genetic and environmental factors that affect these entities through a heterogeneous group of disease ...
Peterson, Randall T, Walcott, Brian P
core +1 more source
Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance
Small GTPases regulate cytoskeletal dynamics, cell motility, and division under precise spatiotemporal control. Different small GTPases exhibit cross talks to exert feedback response or to act in concert during signal transduction.
Yuxing Huang +3 more
doaj +1 more source
The potential of water reuse for agricultural irrigation in the EU: A Hydro-Economic Analysis [PDF]
Policy context Water reuse has been identified by the European Commission as a relevant solution to be further promoted in the EU to address water scarcity.
ALCALDE SANZ LAURA +8 more
core +2 more sources
The Impact of Orography and Latent Heating on the Location of the Tropical Easterly Jet [PDF]
The Tropical Easterly Jet (TEJ) is a prominent atmospheric circulation feature observed during the Asian Summer Monsoon. It is generally assumed that Tibet is an essential ingredient in determining the location of the TEJ.
Rao, Samrat, Srinivasan, J.
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