Results 81 to 90 of about 2,293 (187)

Mann-Whitney U-Test Scores and for the probability values of equality of medians (p), for comparisons of CCM2 scores of birds and sauropods, and the CCM2 scores of birds from different environments.

, 2012
Mann-Whitney U-Test Scores and for the probability values of equality of medians (p), for comparisons of CCM2 scores of birds and sauropods, and the CCM2 scores of birds from different environments.
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

Use of Single‐Cell Data and scPagwas Analysis to Identify T Cell Subsets and Construct a Prognostic Model for Clear Cell Renal Cell Carcinoma

Human Mutation, Volume 2026, Issue 1, 2026.
Background Clear cell renal cell carcinoma (KIRC), the most prevalent pathological renal cell carcinoma (RCC) subtype, makes up approximately 75%–84% of total cases. KIRC is characterized by high heterogeneity, high metastasis rates, and a poor prognosis. Its incidence rate has continued to rise in recent years.
Xincheng Yi, Zongming Jia, Jixiang Wu, Siyu Wang, Yiqi Yu, Ying Kong, Xuefeng He, Yuhua Huang, Harleen Khatra   +8 more
wiley   +1 more source

The geographical distribution and completeness (CCM2) of Mesozoic bird species.

, 2012
(A) The number of avian species found in each landmass; (B) the mean CCM2 score of the avian species found on each landmass. Landmasses formerly part of Laurasia are represented by red bars, while those formerly part of Gondwana are represented by blue ...
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

ccm2-like is required for cardiovascular development as a novel component of the Heg-CCM pathway

Developmental Biology, 2013
The Heart of Glass-Cerebral Cavernous Malformation (Heg-CCM) pathway is essential for normal cardiovascular development in zebrafish and mouse. In zebrafish, the Heg-CCM pathway mutants santa(ccm1/san), valentine (ccm2/vtn), and heart of glass (heg) exhibit severely dilated hearts and inflow tracts and a complete absence of blood circulation.
Rosen, Jonathan N., Sogah, Vanessa M., Ye, Lillian Y., Mably, John D.   +3 more
openaire   +2 more sources

Multiple Genomic Technologies Validate Rare Novel Variant and Direct Medical Care in Vascular Anomalies

American Journal of Medical Genetics Part A, Volume 197, Issue 11, November 2025.
ABSTRACT Some vascular anomalies, such as hamartomas associated with PTEN hamartoma tumor syndrome (PHTS) and fibroadipose vascular anomaly (FAVA, often due to PI3KCA variants), share similar clinical, radiological, and histopathological presentations that challenge clinicians to provide an accurate diagnosis.
Luciana Daniela Garlisi Torales, Kristina Woodis, Allison Britt, Lea F. Surrey, Abhay Srinivasan, Arupa Ganguly, Maria Limmina, Dong Li, Suzanne P. MacFarland, Denise M. Adams, Sarah E. Sheppard   +10 more
wiley   +1 more source

The mean CCM2 scores for birds found in three different palaeoenvironments: marine, fluviolacustrine, and non-fluviolactustrine terrestrial evnvironments.

, 2012
The mean CCM2 scores for birds found in three different palaeoenvironments: marine, fluviolacustrine, and non-fluviolactustrine terrestrial evnvironments.
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

An X‐ray beamline for utilizing intense, high‐energy undulator radiation

Journal of Synchrotron Radiation, Volume 32, Issue 5, Page 1201-1210, September 2025.
The design, development and performance of an X‐ray beamline for utilizing intense, high‐energy undulator radiation are presented.The design, development and performance of an X‐ray beamline for utilizing intense, high‐energy undulator radiation are presented.
Hirokatsu Yumoto, Takahisa Koyama, Hiroshi Yamazaki, Yasunori Senba, Yujiro Hayashi, Taito Osaka, Ichiro Inoue, Kenji Tamasaku, Shunji Goto, Makina Yabashi, Haruhiko Ohashi   +10 more
wiley   +1 more source

Cerebral Cavernous Malformations and Focal Drug‐Resistant Epilepsy: Behind a Quid Pro Quo of Lesion and Epileptogenic Networks

European Journal of Neurology, Volume 32, Issue 7, July 2025.
ABSTRACT Background Cerebral cavernous malformations (CCMs) contribute to focal drug‐resistant epilepsy (fDRE), with surgical outcomes varying due to an incomplete understanding of the interplay between CCM‐impacted regions and areas exhibiting ictal or interictal epileptogenicity.
Ionuț‐Flavius Bratu, Lucie de Clerck, Hélène Catenoix, Luc Valton, Jérôme Aupy, Anca Nica, Sylvain Rheims, Sandrine Aubert‐Conil, Jeanne Benoit, Julia Makhalova, Ophélie Galli, Samuel Medina Villalon, Fabrice Bartolomei   +12 more
wiley   +1 more source

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity. [PDF]

J Cell Biol
We previously identified talin rod domain-containing protein 1 (TLNRD1) as a potent actin-bundling protein in vitro. Here, we report that TLNRD1 is expressed in the vasculature in vivo. Its depletion leads to vascular abnormalities in vivo and modulation
Ball NJ, Ghimire S, Follain G, Pajari AO, Wurzinger D, Vaitkevičiūtė M, Cowell AR, Berki B, Ivaska J, Paatero I, Goult BT, Jacquemet G.   +11 more
europepmc   +2 more sources

Programmed Cell Death Protein 10 (PDCD10) Regulates Vesicle Trafficking and Contributes to the Progression of Clear Cell Renal Cell Carcinoma

Journal of Extracellular Vesicles, Volume 14, Issue 6, June 2025.
ABSTRACT Vesicle trafficking is an essential cellular process that plays an important role in tumour progression. Here, we performed a comprehensive transcriptomic and proteomic analysis on 50 clear cell renal cell carcinoma (ccRCC) tumour samples, and the data systematically depicted the alterations in the molecular landscape.
Rui Wang, Tianyu Lin, Yi Liu, Hao Wang, Xinyu Liu, Yihan Dong, Jiaxin Li, Huamao Jiang, Ruibing Chen, Yong Wang, Dan Yue   +10 more
wiley   +1 more source