Results 71 to 80 of about 2,293 (187)
The FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
A comparison of observed (HALOE) and modeled (CCM2) methane and stratospheric water vapor [PDF]
Recent measurements (21 September - 15 October 1992) of methane and water vapor by the Halogen Occultation Experiment (HALOE) on the Upper Atmosphere Research Satellite (UARS) are compared with model results for the same season from a troposphere-middle ...
Holton, James R. +3 more
core +2 more sources
Europe's Ecological Debt: Mapping Freshwater Restoration Needs
Global Change Biology, Volume 32, Issue 3, March 2026.We used data from the Habitats Directive and the Water Framework Directive to assess freshwater‐related restoration needs across Europe using the Composite Indicator of Conservation Status. Freshwater restoration needs are widespread, with over 94% of River Restoration Units (R2U) showing unfavourable conservation status under at least one of the two ...
Gonçalo Duarte +9 more
wiley +1 more source
Magnetic Resonance Imaging of KRIT1 Associated Familial Cerebral Cavernous Malformations at 7‐Tesla
Neurology and Clinical Neuroscience, EarlyView.
Sam J. Neilson +3 more
wiley +1 more source
Sensitivity of a physically-based cloud package in the NCAR/CCM2 [PDF]
, 1997 Based on our earlier investigation on the performance of the National Center for Atmospheric Research Community Climate Model Version 2 (CCM2), we have incorporated into this model a physically-based cloud package.
Smith, W. S., Kao, Chih-Yue Jim
core
Cerebral Cavernous Malformation 2 Protein Promotes Smad Ubiquitin Regulatory Factor 1-mediated RhoA Degradation in Endothelial Cells [PDF]
, 2009 Mutation of CCM2 predisposes individuals to cerebral cavernous malformations, vascular abnormalities that cause seizures and hemorrhagic stroke. CCM2 has been proposed to regulate the activity of RhoA for maintenance of vascular integrity.
Hilder, Thomas L. +3 more
core +1 more source
EMBO Molecular Medicine, 2018 Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in the regulatory networks of endothelial
Cécile Otten +20 more
doaj +1 more source
The number of fluvialolacustrine bird-bearing localities in each substage compared to mean CCM2.
, 2012 The number of fluvialolacustrine bird-bearing localities in each substage compared to mean CCM2.
Neil Brocklehurst (156277) +3 more
core +1 more source
Medicine, 2020 Abstract Rationale: Cerebral cavernous malformation (CCM) of the familial type is caused by abnormalities in the CCM1, CCM2, and CCM3 genes. These 3 proteins forming a complex associate with the maintenance of vascular endothelial cell-cell junctions.
Kazuhiro Ishii +4 more
openaire +2 more sources
Molecular Diagnosis in a Specialised Neurogenetic Clinic With Access to Whole‐Genome Sequencing
Acta Neurologica Scandinavica, Volume 2026, Issue 1, 2026.Background Rare diseases, collectively affecting 1 in 17 people in the United Kingdom and Ireland, require coordinated care. Specialised multidisciplinary clinics offer a streamlined approach for diagnosis and management of rare neurogenetic disorders.
Patrick B. Moloney +2 more
wiley +1 more source