Results 91 to 100 of about 2,293 (187)

A comparison of sea level [53] and the mean CCM2 scores of Mesozoic bird specimens.

, 2012
A comparison of sea level [53] and the mean CCM2 scores of Mesozoic bird specimens.
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

Defective autophagy is a key feature of cerebral cavernous malformations

EMBO Molecular Medicine, 2015
Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal ...
Saverio Marchi, Mariangela Corricelli, Eliana Trapani, Luca Bravi, Alessandra Pittaro, Simona Delle Monache, Letizia Ferroni, Simone Patergnani, Sonia Missiroli, Luca Goitre, Lorenza Trabalzini, Alessandro Rimessi, Carlotta Giorgi, Barbara Zavan, Paola Cassoni, Elisabetta Dejana, Saverio Francesco Retta, Paolo Pinton   +17 more
doaj   +1 more source

The number and mean CCM2 score of Mesozoic bird species found within modern latitudinal bins.

, 2012
(A) The number of species found in each 5° latitudinal bin; (B) – the mean CCM2 score of all birds (blue curve) found in each latitudinal bin, with the number of specimens (red curve) to indicate sample size.
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

Genetic variations within KRIT1/CCM1, MGC4607/CCM2 and PDCD10/CCM3 in a large italian family harbouring a krit1/CCM1 mutation

, 2010
Cerebral cavernous malformations (CCMs) are congenital vascular anomalies of the central nervous system that can result in seizures, haemorrhage, recurrent headaches and focal neurologic deficit.
Patrosso M. C., Marocchi A., Brunori P., Buscone S., Battistini S., Ricci C., Penco S., Pileggi S.   +7 more
core   +2 more sources

A comparison of the CCM2 scores of Mesozoic bird specimens and that of sauropodomorph specimens [38].

, 2012
A comparison of the CCM2 scores of Mesozoic bird specimens and that of sauropodomorph specimens [38].
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity [PDF]

, 2010
Endothelial cell-cell junctions regulate vascular permeability, vasculogenesis, and angiogenesis. Familial cerebral cavernous malformations (CCMs) in humans result from mutations of CCM2 (malcavernin, OSM, MGC4607), PDCD10 (CCM3), or KRIT1 (CCM1), a Rap1
Robert Shenkar, Stockton, Rebecca A, Awad, Issam A, Rebecca A. Stockton, Issam A. Awad, Ginsberg, Mark H, Mark H. Ginsberg, Shenkar, Robert   +7 more
core   +1 more source

CCM proteins control endothelial β1 integrin dependent response to shear stress

Biology Open, 2014
Hemodynamic shear stress from blood flow on the endothelium critically regulates vascular function in many physiological and pathological situations. Endothelial cells adapt to shear stress by remodeling their cytoskeletal components and subsequently by ...
Zuzana Macek Jilkova, Justyna Lisowska, Sandra Manet, Claude Verdier, Valerie Deplano, Christian Geindreau, Eva Faurobert, Corinne Albigès-Rizo, Alain Duperray   +8 more
doaj   +1 more source

Visualization Of The Community Climate Model (ccm2)

, 1994
This project involved post processing and analysis of the Community Climate Model outputs. The most direct way of going over the data is to visualize the data as graphical pictures or graphs.
Michael E. Jebb
core  

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

, 2009
Cerebral cavernous malformations (CCMs) are human vascular malformations caused by mutations in three genes of unknown function: KRIT1, CCM2 and PDCD10. Here we show that the heart of glass (HEG1) receptor, which in zebrafish has been linked to ccm gene ...
Markus Affolter, Blum, Y., Guo, L., Jian J Liu, Kleaveland, B., Zheng, X., Benjamin Kleaveland, Chen, M., Kahn, M. L., Jennifer J Tung, Ginsberg, M. H., Affolter, M., Xiangjian Zheng, Jan Kitajewski, Zhiying Zou, Mei Chen, Tung, J. J., Yannick Blum, Sweeney, S. M., Zou, Z., Liu, J. J., Kitajewski, J., Mark H Ginsberg, Min-min Lu, Mark L Kahn, Lu, M. -min, Lili Guo, Zhou, D., Shawn M Sweeney, Diane Zhou, Zhou, Diane, Sweeney, Shawn M, Ginsberg, Mark H, Blum, Yannick, Zheng, Xiangjian, Affolter, Markus, Kahn, Mark L, Lu, Min-min, Kitajewski, Jan, Guo, Lili, Liu, Jian J, Chen, Mei, Zou, Zhiying, Kleaveland, Benjamin, Tung, Jennifer J   +44 more
core   +1 more source

Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance

Cells, 2019
Small GTPases regulate cytoskeletal dynamics, cell motility, and division under precise spatiotemporal control. Different small GTPases exhibit cross talks to exert feedback response or to act in concert during signal transduction.
Yuxing Huang, Xin Yi, Chenlu Kang, Congying Wu   +3 more
doaj   +1 more source