Results 101 to 110 of about 1,951 (186)

Fare meme kanseri modeli primer tümör ve metastazlarında CCM1, CCM2, CCM3 ekspresyonlarının değerlendirilmesi [PDF]

, 2017
Amaç: CCM1, CCM2 ve CCM3 genlerinde tanımlanan mutasyonlar sporadik ya da kalıtsal olup santral sinir sisteminde görülen serebral kavernoz malformasyonların (SKM) sebebidir.
Cici, Mansur
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GERM-LINE/SOMATIC DNA COMPARISON IN SPORADIC PATIENTS WITH CEREBRAL CAVERNOUS MALFORMATIONS.

Euromediterranean Biomedical Journal, 2017
Cerebral cavernous malformations (CCMs) are benign tumours that affect brain capillaries. Although many cases remain asymptomatic, their incidence is steadily increasing.
Ivan Anchesi
doaj   +1 more source

CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading

, 2017
Atrial natriuretic peptide (ANP) is a cardiac hormone released by the atrium in response to stretching forces. Via its receptor, guanylyl cyclase-A (GC-A), ANP maintains cardiovascular homeostasis by exerting diuretic, natriuretic, and hypotensive ...
Masahiro Zenitani, Mikiya Miyazato, Yoshiharu Akitake, Toru Kimura, Jun Hino, Koji Ando, Koichi Miura, Hiroshi Hosoda, Kenji Kangawa, Shigetomo Fukuhara, Takashi Nojiri   +10 more
core   +1 more source

The seasonal cycle of atmospheric CO2: A study based on the NCAR community climate model (CCM2)

, 2017
A global three-dimensional atmospheric model, the NCAR CCM2 general circulation model, has been adapted to study the hourly to yearly variability of CO2 in the atmosphere.
Tans, P.P., Ciais, P., Rasch, P.J., Maier-Reimer, E., Erickson, D.J., Six, K., Friedlingstein, P., Walters, S., Fischer, C.A.   +8 more
core   +3 more sources

Comparison of the data collected by Fountaine et al. [37] with the CCM2.

, 2012
(A) Modified from Fountaine et al.'s [37] assessment of the completeness of the fossil record of Mesozoic birds (bird species with a completeness grade of 1 are represented by one bone, those with 2 by more than one bone, those with 3 by a nearly ...
Neil Brocklehurst (156277), Jingmai O'Connor (156296), Philip D. Mannion (156289), Paul Upchurch (156283)   +3 more
core   +1 more source

P016 | A novel insight into the role of CCM genes in myeloproliferative neoplasms

Haematologica
Introduction. Myeloid neoplasms (MNs) are clonal hematologic disorders characterized by chronic inflammation, oxidative stress, and increased risk of fibrotic and cardiovascular complications.
Cristina Panuzzo
doaj  

A Novel CCM3 Mutation Associated with a Severe Clinical Course in a Child with Multiple Cerebral Cavernous Malformations

Journal of Vascular Diseases
Background: Cerebral cavernous malformations (CCMs) are vascular lesions linked to mutations in the CCM1, CCM2, and CCM3 genes, resulting in angiogenesis dysregulation.
Olga Belousova, Denis Semenov, Eugenia Boulygina, Svetlana Tsygankova, Alexander Konovalov   +4 more
doaj   +1 more source

Summary of distributions of Character Completeness Metric 2 (CCM2) values for squamates found in established lagerstätten localities, with a summary of the number of families represented in localities using the Gauthier et al. (2012) [69] phylogeny.

A) Distribution of CCM2 values and number of families of squamates found in the Upper Cretaceous Smoky Hill Chalk. Example species: Platecarpus tympaniticus [89].
Frank A. Corsetti (5282120), C. Henrik Woolley (17965460), Nathan D. Smith (239732), David J. Bottjer (3268407)   +3 more
core   +1 more source

Cerebral Cavernous Malformation 2 Protein Promotes Smad Ubiquitin Regulatory Factor 1-mediated RhoA Degradation in Endothelial Cells

, 2009
Mutation of CCM2 predisposes individuals to cerebral cavernous malformations, vascular abnormalities that cause seizures and hemorrhagic stroke. CCM2 has been proposed to regulate the activity of RhoA for maintenance of vascular integrity.
Hilder, Thomas L., Sciaky, Noah, Johnson, Gary L., Crose, Lisa E.S.   +3 more
core   +2 more sources

Zerebrale Kavernomatose - Identifizierung tief-intronischer Varianten in den genomischen Regionen von CCM1, CCM2 und CCM3 mittels Hochdurchsatzsequenzierung [PDF]

, 2016
Zerebrale kavernöse Malformationen (CCM) sind autosomal-dominant vererbbare zerebrovaskuläre Fehlbildungen, die mit unvollständiger Penetranz zu Kopfschmerzen, Krampfanfällen und hämorrhagischen Schlaganfällen führen können.
Jenssen, Sönke Elisabeth
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