Results 151 to 160 of about 54,562 (253)

CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions.

PLoS Pathogens
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion that could be targeted to ameliorate disease severity.
Laís Amorim Sacramento, Camila Farias Amorim, Claudia G Lombana, Daniel Beiting, Fernanda Novais, Lucas P Carvalho, Edgar M Carvalho, Phillip Scott   +7 more
doaj   +1 more source

CCR5 gene editing – Revisiting pros and cons of CCR5 absence

Infection, Genetics and Evolution, 2019
Joel Henrique Ellwanger, Valéria de Lima Kaminski, José Artur Bogo Chies   +2 more
openaire   +2 more sources

Molecular Determinants of CCR5-Tropic Human Immunodeficiency Virus 1 Entry Into Low-CCR5 Expressing Cells

, 2018
Over 80 million people have been infected with Human Immunodeficiency Virus 1 (HIV-1) worldwide. Despite advances in the treatment of HIV-1 infected individuals, practical cure or prevention of HIV-1 infections has not been achieved.
Espy, Nicole Joy
core  

Seeing CCR5 [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

CCR5+ CD8+ T Cells Are Associated with Poor Response to PD-1 Blockade Therapy. [PDF]

Int J Mol Sci
Zhao Z, Liu Y, Wu Z, Qi C, Ning Y, Lin Y, Pang X, Qiang G, Wang W.   +8 more
europepmc   +1 more source

Refined single-cell profiling captures a CCR5^high CD4⁺ cytotoxic T-cell precursor in multiple sclerosis. [PDF]

EBioMedicine
van Puijfelik F, Rip J, van Hasselt Y, Wierenga-Wolf AF, Shyfrin S, Pelser AC, Melief MJ, Klein Kranenbarg RAM, Bindels EM, van de Werken HJG, van Ansenwoude CMJ, de Vries HE, Dik WA, de Beukelaar J, Smets I, Wokke BH, Smolders J, van Luijn MM.   +17 more
europepmc   +1 more source

Chemokine receptor expression defines a trajectory from monocytes to mature macrophages in the lung. [PDF]

J Leukoc Biol
Mathie H, Medina-Ruiz L, Schuette F, Halawa H, Pocalun Z, Pitmon E, Cole J, Pingen M, Graham GJ.   +8 more
europepmc   +1 more source

Donor macrophage depletion permits posttransplant tolerance induction in a murine islet transplant model. [PDF]

Am J Transplant
Dilts M, Fay OK, Yu Y, Jordan CZ, Luo X.
europepmc   +1 more source

Targeting the CCL5/CCR5-PI3K-AKT axis suppresses hepatic stellate cell-induced breast cancer metastasis. [PDF]

Cancer Cell Int
Huang H.
europepmc   +1 more source

Morphine potentiates HIV infection and receptor expression in 3d brain organoids. [PDF]

J Neurovirol
Swingler M, Tasdemir D, Cakir S, Bellizzi A, Donadoni M, Sariyer IK.   +5 more
europepmc   +1 more source