Results 161 to 170 of about 87,303 (273)

β-Chemokine Receptor CCR5 Signals Via the Novel Tyrosine Kinase RAFTK [PDF]

, 1998
Ramesh K. Ganju, Parmesh Dutt, Lijun Wu, Walter Newman, Hava Avraham, Shalom Avraham, Jerome E. Groopman   +6 more
openalex   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, Volume 182, Issue 17, Page 3975-3989, September 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Tissue‐Resident T Cells That Promote Humoral Immunity: Emerging From the Shadow of T Follicular Helper Cells

Immunological Reviews, Volume 334, Issue 1, September 2025.
ABSTRACT Humoral immune responses are critical for protection against immune challenge by pathogens and transformed cells, while dysregulated antibody production is a hallmark of autoimmune diseases. T follicular helper (Tfh) cells are central to the development of humoral immunity, regulating B‐cell maturation, including immunoglobulin class switch ...
Shuting Chen, Joseph Craft
wiley   +1 more source

Human Vascular Smooth Muscle Cells Possess Functional CCR5 [PDF]

, 2000
Alison D. Schecter, Tina M. Calderon, Adriane B. Berman, Carrie M. McManus, John T. Fallon, Maria Rossikhina, Weixin Zhao, George J. Christ, Joan W. Berman, Mark B. Taubman   +9 more
openalex   +1 more source

CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions.

PLoS Pathogens
Cytolytic CD8+ T cells mediate immunopathology in cutaneous leishmaniasis without controlling parasites. Here, we identify factors involved in CD8+ T cell migration to the lesion that could be targeted to ameliorate disease severity.
Laís Amorim Sacramento, Camila Farias Amorim, Claudia G Lombana, Daniel Beiting, Fernanda Novais, Lucas P Carvalho, Edgar M Carvalho, Phillip Scott   +7 more
doaj   +1 more source

Prognostic Value of a CCR5 Defective Allele in Pediatric HIV-1 Infection [PDF]

, 2000
Maria Luisa Romiti, Claudia Colognesi, Caterina Cancrini, Antonio Más, M. Berrino, Francesca Salvatori, Paola Orlandi, Marianne Jansson, Elvia Palomba, A Plebani, J.M. Bertrán, M. Hernández, Maurizio de Martino, Antonio Amoroso, Pier‐Angelo Tovo, Paolo Rossi, Teresa Español, Gabriella Scarlatti   +17 more
openalex   +1 more source

Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry

, 1997
Zhiwei Chen, Pingping Zhou, David D. Ho, Nathaniel R. Landau, Preston A. Marx   +4 more
openalex   +1 more source

Contrasting Effects of CCR5 and CCR2 Deficiency in the Pulmonary Inflammatory Response to Influenza A Virus [PDF]

, 2000
Tracey C. Dawson, Melinda A. Beck, William A. Kuziel, Fred Henderson, Nobuyo Maeda   +4 more
openalex   +1 more source

N-Linked Glycosylation of CXCR4 Masks Coreceptor Function for CCR5-Dependent Human Immunodeficiency Virus Type 1 Isolates [PDF]

, 2000
Donald J. Chabot, Hong Chen, Dimiter S. Dimitrov, Christopher C. Broder   +3 more
openalex   +1 more source

CCR5 gene editing – Revisiting pros and cons of CCR5 absence

Infection, Genetics and Evolution, 2019
Joel Henrique Ellwanger, Valéria de Lima Kaminski, José Artur Bogo Chies   +2 more
openaire   +3 more sources