Harnessing <i>Streptomyces</i> for the Management of Clubroot Disease of Chinese Cabbage (<i>Brassica rapa</i> subsp. <i>Pekinensis</i>). [PDF]
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CD1 was originally defined as a cluster of mAb directed against leukocyte surface determinants. The antigens recognised appeared to share three main features: a restricted tissue expression (cortical thymocytes and some dendritic cells), a structure consisting of a heterodimer of an alpha chain of- 45 kDa associated with beta-2 microglobulin (b2m) and ...
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CD1 assembly and the formation of CD1–antigen complexes
Current Opinion in Immunology, 2005The CD1 antigen presentation system presents lipid antigens to effector T cells, which have diverse roles in antimicrobial responses, antitumor immunity and in regulating the balance between tolerance and autoimmunity. The trafficking of CD1 molecules and lipid antigens facilitates their intersection and binding in specific intracellular compartments ...
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