Results 191 to 200 of about 48,670 (240)
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CD1 and CD1-restricted T cells in infections with intracellular bacteria
Trends in Microbiology, 2000Glycolipid-specific, CD1a-, b- and c-dependent cytotoxic T cells have recently been shown to be involved in the host response against tuberculosis. These CD1 molecules 'sample' mycobacterial glycolipids from different intracellular sites in the infected cell. Additionally, upon microbial encounter, CD1d-dependent natural killer T cells promptly produce
Ulrich E Schaible, Stefan H E Kaufmann
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Tissue Antigens, 1991
CD1 was originally defined as a cluster of mAb directed against leukocyte surface determinants. The antigens recognised appeared to share three main features: a restricted tissue expression (cortical thymocytes and some dendritic cells), a structure consisting of a heterodimer of an alpha chain of- 45 kDa associated with beta-2 microglobulin (b2m) and ...
Calabi F, Bradbury A
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CD1 was originally defined as a cluster of mAb directed against leukocyte surface determinants. The antigens recognised appeared to share three main features: a restricted tissue expression (cortical thymocytes and some dendritic cells), a structure consisting of a heterodimer of an alpha chain of- 45 kDa associated with beta-2 microglobulin (b2m) and ...
Calabi F, Bradbury A
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CD1 assembly and the formation of CD1–antigen complexes
Current Opinion in Immunology, 2005The CD1 antigen presentation system presents lipid antigens to effector T cells, which have diverse roles in antimicrobial responses, antitumor immunity and in regulating the balance between tolerance and autoimmunity. The trafficking of CD1 molecules and lipid antigens facilitates their intersection and binding in specific intracellular compartments ...
David L, Hava +5 more
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CD1 molecules: Beyond antigen presentation
Molecular ImmunologyCD1 molecules are well known for their role in binding and presenting lipid antigens to mediate the activation of CD1-restricted T cells. However, much less appreciated is the fact that CD1 molecules can have additional "unconventional" roles which ...
Patricia Barral
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Spin correlation and dynamics of excitons in Cd1−MnTe, Cd1−MnSe and Cd1−CoSe
Journal of Crystal Growth, 1992Abstract By time resolved and optical spin orientation spectroscopies of band-edge luminescences, an exchange interaction of excitons with magnetic ions was studied in semimagnetic semiconductors. The exchange interaction gives rise to a marked increase of the exciton luminescence intensity in magnetic fields as well as a dynamical formation process ...
Yasuo Oka +3 more
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Seminars in Immunology, 2000
CD1 were the first human differentiation antigens to be identified by monoclonal antibodies. In this review, we summarize some key results from the molecular study of CD1, with particular reference to their relationship to MHC antigens, and to the existence of two distinct groups of CD1 molecules.
Calabi F, Milstein C
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CD1 were the first human differentiation antigens to be identified by monoclonal antibodies. In this review, we summarize some key results from the molecular study of CD1, with particular reference to their relationship to MHC antigens, and to the existence of two distinct groups of CD1 molecules.
Calabi F, Milstein C
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2007
The CD1 family of glycosylated cell surface receptors binds and presents lipid antigens for T cell recognition and activation. Crystal structures of CD1-lipid complexes reveal differences in the mode of presentation of lipids by CD1 group 1 (CDla, CDlb, and CDlc) and group 2 isoforms (CDld).
D M, Zajonc, I A, Wilson
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The CD1 family of glycosylated cell surface receptors binds and presents lipid antigens for T cell recognition and activation. Crystal structures of CD1-lipid complexes reveal differences in the mode of presentation of lipids by CD1 group 1 (CDla, CDlb, and CDlc) and group 2 isoforms (CDld).
D M, Zajonc, I A, Wilson
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Primary immunodeficiency associated with defects in CD1 and CD1‐restricted T cells
Annals of the New York Academy of Sciences, 2012CD1 is a family of atypical MHC class I molecules that present various endogenous and exogenous lipid antigens to CD1‐restricted T cells. While little is known about the function of CD1a‐, CD1b‐, and CD1c‐restricted lipid‐reactive T cells due to their absence in mice, CD1d‐restricted natural killer T (NKT) cells have been extensively studied since ...
Sebastian, Zeissig, Richard S, Blumberg
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Analysis of the CD1 cluster in sheep
Veterinary Immunology and Immunopathology, 1991The anti-CD1 monoclonal antibodies submitted to the 1st International Workshop on Leucocyte Differentiation Antigens of Cattle, Sheep and Goats were tested for their reactivity on sheep skin, thymus and lymph node and for their reactivity with sheep efferent and afferent lymph and peripheral blood. With the exception of 20-27 they all stained that same
B M, Dutia, J, Hopkins
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