Results 201 to 210 of about 51,555 (247)
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CD1 and CD1-restricted T cells in infections with intracellular bacteria
Trends in Microbiology, 2000Glycolipid-specific, CD1a-, b- and c-dependent cytotoxic T cells have recently been shown to be involved in the host response against tuberculosis. These CD1 molecules 'sample' mycobacterial glycolipids from different intracellular sites in the infected cell. Additionally, upon microbial encounter, CD1d-dependent natural killer T cells promptly produce
Schaible, U., Kaufmann, S.
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Tissue Antigens, 1991
CD1 was originally defined as a cluster of mAb directed against leukocyte surface determinants. The antigens recognised appeared to share three main features: a restricted tissue expression (cortical thymocytes and some dendritic cells), a structure consisting of a heterodimer of an alpha chain of- 45 kDa associated with beta-2 microglobulin (b2m) and ...
Calabi F, Bradbury A
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CD1 was originally defined as a cluster of mAb directed against leukocyte surface determinants. The antigens recognised appeared to share three main features: a restricted tissue expression (cortical thymocytes and some dendritic cells), a structure consisting of a heterodimer of an alpha chain of- 45 kDa associated with beta-2 microglobulin (b2m) and ...
Calabi F, Bradbury A
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CD1 assembly and the formation of CD1–antigen complexes
Current Opinion in Immunology, 2005The CD1 antigen presentation system presents lipid antigens to effector T cells, which have diverse roles in antimicrobial responses, antitumor immunity and in regulating the balance between tolerance and autoimmunity. The trafficking of CD1 molecules and lipid antigens facilitates their intersection and binding in specific intracellular compartments ...
David L, Hava +5 more
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Spin correlation and dynamics of excitons in Cd1−MnTe, Cd1−MnSe and Cd1−CoSe
Journal of Crystal Growth, 1992Abstract By time resolved and optical spin orientation spectroscopies of band-edge luminescences, an exchange interaction of excitons with magnetic ions was studied in semimagnetic semiconductors. The exchange interaction gives rise to a marked increase of the exciton luminescence intensity in magnetic fields as well as a dynamical formation process ...
Yasuo Oka +3 more
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2007
The CD1 family of glycosylated cell surface receptors binds and presents lipid antigens for T cell recognition and activation. Crystal structures of CD1-lipid complexes reveal differences in the mode of presentation of lipids by CD1 group 1 (CDla, CDlb, and CDlc) and group 2 isoforms (CDld).
D M, Zajonc, I A, Wilson
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The CD1 family of glycosylated cell surface receptors binds and presents lipid antigens for T cell recognition and activation. Crystal structures of CD1-lipid complexes reveal differences in the mode of presentation of lipids by CD1 group 1 (CDla, CDlb, and CDlc) and group 2 isoforms (CDld).
D M, Zajonc, I A, Wilson
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Primary immunodeficiency associated with defects in CD1 and CD1‐restricted T cells
Annals of the New York Academy of Sciences, 2012CD1 is a family of atypical MHC class I molecules that present various endogenous and exogenous lipid antigens to CD1‐restricted T cells. While little is known about the function of CD1a‐, CD1b‐, and CD1c‐restricted lipid‐reactive T cells due to their absence in mice, CD1d‐restricted natural killer T (NKT) cells have been extensively studied since ...
Sebastian, Zeissig, Richard S, Blumberg
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Analysis of the CD1 cluster in sheep
Veterinary Immunology and Immunopathology, 1991The anti-CD1 monoclonal antibodies submitted to the 1st International Workshop on Leucocyte Differentiation Antigens of Cattle, Sheep and Goats were tested for their reactivity on sheep skin, thymus and lymph node and for their reactivity with sheep efferent and afferent lymph and peripheral blood. With the exception of 20-27 they all stained that same
B M, Dutia, J, Hopkins
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Expression of CD1 in the mouse thymus
European Journal of Immunology, 1990AbstractThe CD1 antigens are a family of differentiation antigens found predominantly, but not exclusively, in the human thymus. Although three antigens (CD1a–c) are described by monoclonal antibodies, five genes (CD1A–E) are found in the human genome. The cloning of the mouse CD1 genes (Bradbury, A., Belt, K. T., Nery, T. M., Milstein, C.
Bradbury A, Calabi F, Milstein C
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Low-temperature refractive indices of Cd1−xMnxTe and Cd1−yMgyTe
Journal of Applied Physics, 1997The refractive indices of Cd1−xMnxTe and Cd1−yMgyTe (0<x<0.28 and 0<y<0.70) were determined by analyzing interference fringes in reflectivity spectra of thin films grown by molecular beam epitaxy. It is shown that their dispersions in the transparent region at 4 K are well described by a Sellmeier relation.
Andre, R., Dang, Le Si
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Veterinary Immunology and Immunopathology, 2000
Interest in CD1 genes and proteins was initially stimulated by their close evolutionary and structural relationship to MHC class I molecules. The demonstration that CD1b and c molecules present novel non-peptide antigens to T-cells and play a role in protection against mycobacterial infection then focused attention on the functional role of CD1 ...
J, Hopkins, B M, Dutia, S M, Rhind
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Interest in CD1 genes and proteins was initially stimulated by their close evolutionary and structural relationship to MHC class I molecules. The demonstration that CD1b and c molecules present novel non-peptide antigens to T-cells and play a role in protection against mycobacterial infection then focused attention on the functional role of CD1 ...
J, Hopkins, B M, Dutia, S M, Rhind
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