TLR2-induced surface mobilization and release of CD14 in human platelets [PDF]
Scientific ReportsIn addition to hemostasis, platelets are involved in immunological processes and express toll-like receptors (TLR) like TLR2 and TLR4. Since CD14 represents an essential co-receptor for TLR in immune cells, this study investigated the presence, the ...
Anna Kobsar +7 more
doaj +2 more sources
Journal of Asthma and Allergy, 2013 ZongYao Wang,1 John S Sundy,1 Catherine M Foss,1 Huiman X Barnhart,2 Scott M Palmer,1 Sallie D Allgood,3 Evan Trudeau,1 Katie M Alexander,3 Marc C Levesque31Division of Pulmonary, Allergy and Critical Care Medicine, 2Duke Clinical Research Institute ...
Wang ZY +8 more
doaj +3 more sources
Toll-like receptor signaling in vertebrates: Testing the integration of protein, complex, and pathway data in the Protein Ontology framework [PDF]
, 2015 The Protein Ontology (PRO) provides terms for and supports annotation of species-specific protein complexes in an ontology framework that relates them both to their components and to species-independent families of complexes.
Arighi, Cecilia +7 more
core +26 more sources
CD14 GENE AS A CANDIDATE GENE FOR IMMUNOMODULATION : A REVIEW [PDF]
Exploratory Animal and Medical Research, 2012 CD14 molecule and CD14 gene has been characterized in various livestock species. Structural analysis of CD14 molecule and CD14 gene encoding it is helpful for understanding its function for immuno-modulation. CD14 gene has been observed to be highly
Aruna Pa +4 more
doaj +2 more sources
Evaluation of serum levels of CD14 in neonatal sepsis and its correlation with type of infection in Beni-Suef University Hospital [PDF]
Egyptian Journal of Medical Research, 2022 The aim of the present study was to identify the incidence of sepsis among neonates admitted at Beni-Suef University Hospital during the period of the study, to identify different organisms responsible for sepsis and the serum level of CD14 (presepsin ...
Aya Mahmoud +3 more
doaj +1 more source
Effects of Escherichia coli lipopolysaccharide on innate immunity: The expression profile of TLR4 and CD14 genes in rat's liver [PDF]
Open Veterinary Journal, 2021 Background: Bacterial Endotoxin (lipopolysaccharide) is essential for bacterial virulence, as it has a biphasic effect which is either harmful and leads to aseptic shock and death or assists the body defense mechanisms as it stimulates B-cells activation.
Ammar M. Al-Aalim +2 more
doaj +1 more source
Blood monocyte subtypes in patients with pulmonary tuberculosis infection
Al-Azhar Assiut Medical Journal, 2022 Background and aim Monocytes are the primary target for Mycobacterium tuberculosis infection. Important alterations in the proportions of circulating monocyte subpopulations were found in patients with active tuberculosis (aTB).
Tamer G El-Rab Attia +3 more
doaj +1 more source
Role of TLR4 Receptor Complex in the Regulation of the Innate Immune Response by Fibronectin
Cells, 2020 Chronic inflammation and subsequent tissue fibrosis are associated with a biochemical and mechanical remodeling of the fibronectin matrix. Due to its conformational lability, fibronectin is considerably stretched by the contractile forces of the fibrotic
Mingzhe Zheng +2 more
doaj +1 more source
OncoImmunology, 2021 The outcome of patients with cutaneous melanoma has been strongly modified by recent advances obtained with Immune Checkpoint Inhibitors (ICIs). However, despite this breakthrough, durable response to ICIs is limited to a subset of patients.
Marius Ilié +14 more
doaj +1 more source
Effect of Coronin-1 on macrophage polarization by regulating the expression of CD14
Di-san junyi daxue xuebao, 2021 Objective To investigate the correlation between Coronin-1 and macrophage polarization and its possible mechanism. Methods Firstly, M1 and M2 RAW246.7 macrophage cells were established, and the expression of Coronin-1 at mRNA and protein level was ...
FAN Xiaoxia +3 more
doaj +1 more source