Results 21 to 30 of about 188,530 (334)

ACTIVATION AND DIFFERENTIATION OF PERIPHERAL BLOOD MONOCYTES IN PERIODONTITIS

Медицинская иммунология, 2014
Periodontitis is a chronic infectious inflammatory disease, being the most common bone disease in humans. Porphyromonas gingivalis bacteria are quite common in periodontal lesions, thus considered among major causal agents of periodontitis.
L. M. Tebloeva, O. A. Guseva, S. V. Philippov, S. V. Khaidukov   +3 more
doaj   +1 more source

Soluble CD14 in periodontitis [PDF]

Innate Immunity, 2009
Lipopolysaccharide (LPS) binds to soluble (s)CD14. We investigated which factors contribute to variations in sCD14 levels in periodontitis, a chronic infectious disease of tooth-supporting tissues associated with endotoxemia and leading to inflammation and subsequently loss of teeth.
Nicu, E.A., Laine, M.L., Morre, S.A., van der Velden, U., Loos, B.G.   +4 more
openaire   +4 more sources

Signs of Deregulated Gene Expression Are Present in Both CD14+ and CD14- PBMC From Non-Obese Men With Family History of T2DM

Frontiers in Endocrinology, 2021
AimDevelopment of type 2 diabetes (T2DM) is associated with disturbances in immune and metabolic status that may be reflected by an altered gene expression profile of peripheral blood mononuclear cells (PBMC).
Michal Koc, Michaela Šiklová, Michaela Šiklová, Veronika Šrámková, Veronika Šrámková, Marek Štěpán, Marek Štěpán, Eva Krauzová, Eva Krauzová, Vladimír Štich, Vladimír Štich, Vladimír Štich, Lenka Rossmeislová, Lenka Rossmeislová   +13 more
doaj   +1 more source

Low-Density Granulocytes Are a Novel Immunopathological Feature in Both Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder [PDF]

, 2019
Objective: To investigate whether low-density granulocytes (LDGs) are an immunophenotypic feature of patients with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD).
Alexander, Tobias, Asseyer, Susanna, Bellmann-Strobl, Judith, Hauser, Anja E., Koppen, Sofie van, Lindquist, Randall L., Mothes, Ronja, Niesner, Raluca A., Ostendorf, Lennard, Paul, Friedemann, Radbruch, Helena, Ruprecht, Klemens   +11 more
core   +3 more sources

CD14: Chaperone or Matchmaker? [PDF]

Immunity, 2006
In this issue of Immunity, describe a physical and functional relationship between Toll-like receptor 3 (TLR3) and the pattern recognition protein CD14. In the presence of CD14, TLR3-mediated signal transduction events are amplified.
Finberg, Robert W., Kurt-Jones, Evelyn A.   +1 more
openaire   +2 more sources

BLOOD MONOCYTE SUBPOPULATIONS DURING UNCOMPLICATED CORONARY ARTERY BYPASS SURGERY

Медицинская иммунология, 2014
. We have observed thirty-six patients with coronary artery disease (CAD) who have undergone coronary artery bypass graft (CABG) surgery. In patients with uncomplicated clinical course post-CABG, total lymphocyte counts, T-, B- and NK-cell contents did ...
A. S. Golovkin, V. G. Matveeva, I. V. Kudryavtsev, E. V. Grigoriev, E. A. Velikanova, Yu. V. Bairakova   +5 more
doaj   +1 more source

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis [PDF]

, 2014
Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells.
De Bleser, Dominique, De Mulder, Katrien, Kerre, Tessa, Lambrecht, Bart, Leclercq, Georges, Menten, Björn, Philippé, Jan, Taghon, Tom, Van Caeneghem, Yasmine, Van Roy, Nadine, Vandekerckhove, Bart, Vanhee, Stijn, Velghe, Imke, Verstichel, Greet   +13 more
core   +3 more sources

CD14+CD16+ and CD14+CD163+ monocyte subpopulations in kidney allograft transplantation [PDF]

BMC Immunology, 2014
Monocytes represent a heterogeneous population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be characteristically preferentially expressed by immunosuppressive monocytes.
Sekerkova, Alena, Krepsova, Eva, Brabcova, Eva, Slatinska, Janka, Viklicky, Ondrej, Lanska, Vera, Striz, Ilja   +6 more
openaire   +2 more sources

ROLE OF СD14 AND CYTOKINE GENE POLYMORPHISM IN CLINICAL FEATURES AND OUTCOMES OF NOSOCOMIAL PNEUMONIA

Медицинская иммунология, 2014
. This article is devoted to analysis of gene polymorphisms affecting CD14 regulatory molecule, as well as IL-1β, TNFα cytokines and IL-1RN in the patients with nosocomial pneumonias.
E. A. Baygosina, V. I. Sovalkin
doaj   +1 more source

Celiac Disease Monocytes Induce a Barrier Defect in Intestinal Epithelial Cells [PDF]

, 2019
Intestinal epithelial barrier function in celiac disease (CeD) patients is altered. However, the mechanism underlying this effect is not fully understood.
Branchi, Federica, Cardoso-Silva, Danielle, Delbue, Deborah, Itzlinger, Alice, Letizia, Marilena, Schumann, Michael, Siegmund, Britta   +6 more
core   +1 more source