Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis. [PDF]
, 2015 Natural killer (NK) cells are cytotoxic lymphocytes that substantially contribute to the therapeutic benefit of antitumor antibodies like Rituximab, a crucial component in the treatment of B-cell malignancies.
A Kamal +46 more
core +1 more source
The activating receptors 2B4 and NTB-A, but not CRACC are subject to ligand-induced down-regulation on human natural killer cells [PDF]
, 2010 Activation of natural killer cells can be mediated by different receptors. Stimulation of the receptors 2B4, NTB-A and CRACC, members of the SLAM-related receptor family, induces cytotoxicity and cytokine production.
Carolin Böhm +4 more
core +2 more sources
Accelerated tumor growth in mice deficient in DNAM-1 receptor [PDF]
, 2009 課題番号 ...
タハラ サトコ, 田原 聡子
core
SOCS1 Inhibits IL-6-Induced CD155 Overexpression in Lung Adenocarcinoma
International Journal of Molecular SciencesCD155, also known as the poliovirus receptor (PVR), is a crucial molecule in the development and progression of cancer, as its overexpression favors immune evasion and resistance to immunotherapy. However, little is known about the mechanisms that regulate its overexpression.
Mario Marroquin-Muciño +9 more
openaire +2 more sources
Chemotherapy Sensitizes Colon Cancer Initiating Cells to Vc9Vd2 T Cell-Mediated Cytotoxicity [PDF]
, 2013 Colon cancer comprises a small population of cancer initiating stem cells (CIC) that is responsible for tumor maintenance and resistance to anti-cancer therapies, possibly allowing for tumor recapitulation once treatment stops.
CACCAMO, Nadia Rosalia +6 more
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Dendritic Cell Interactions with NK Cells from Different Tissues [PDF]
, 2018 Introduction: In recent years, it has been realized that innate lymphocytes do not act in isolation but potentiate their efficiency by interacting with each other, resulting even in the regulation of adaptive immune response.
Ferlazzo, Guido, Münz, Christian
core
Structural studies on members of the picornavirus superfamily [PDF]
, 2011 The pathogenic members of the picornavirus superfamily have adverse effects on humans, their crops and their livestock. As structure is related to function, detailed structural studies on these viruses are important not only for fundamental understanding
Seitsonen, Jani
core
Prognostic impact of nectin-like molecule-5 (CD155) expression in non-small cell lung cancer
Journal of Translational MedicineBackground CD155 is a transmembrane protein that inhibits antitumor immune response and represents a predictor of worse prognosis in non-small-cell lung cancer (NSCLC).
Xitlally Popa-Navarro +9 more
doaj +1 more source
Inflammatory monocytes and NK cells play a crucial role in DNAM-1-dependent control of cytomegalovirus infection [PDF]
, 2016 Colonna, Marco, et al,
core +2 more sources
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients
BMC ImmunologyBackground Imbalanced immune responses are involved in developing preeclampsia (PE). We wish to explore the expression and potential changes of immune checkpoint molecules TIGIT, CD226 and CD155 in PE patients.
Cui Li, Haiyan Liu, Zhongliang Duan
doaj +1 more source