Results 131 to 140 of about 7,732 (197)

Natural Killer Cells in Cancer Immunotherapy [PDF]

, 2019
Arndt MA, Chester C, Cortez VS, D'Andrea A, Elsasser D, Ferrini S, Gao Y, Hartmann F, Lotze MT, Miller JS, Orr MT, Seillet C, Soiffer RJ, Soto EO, Weiner LM, Yron I   +15 more
core   +1 more source

synNotch-programmed iPSC-derived NK cells usurp TIGIT and CD73 activities for glioblastoma therapy

Nature Communications
Severe heterogeneity within glioblastoma has spurred the notion that disrupting the interplay between multiple elements on immunosuppression is at the core of meaningful anti-tumor responses. T cell immunoreceptor with Ig and ITIM domains (TIGIT) and its
Kyle B. Lupo, Xue Yao, Shambhavi Borde, Jiao Wang, Sandra Torregrosa-Allen, Bennett D. Elzey, Sagar Utturkar, Nadia A. Lanman, MacKenzie McIntosh, Sandro Matosevic   +9 more
doaj   +1 more source

PITPNC1 Suppress CD8+ T cell immune function and promote radioresistance in rectal cancer by modulating FASN/CD155

Journal of Translational Medicine
Background Radioresistance is a primary factor contributing to the failure of rectal cancer treatment. Immune suppression plays a significant role in the development of radioresistance.
Junxian Liang, Limin Liao, Lang Xie, WenWen Tang, Xiang Yu, Yinghao Lu, Hongzhen Chen, Juanli Xu, Lei Sun, Huanmei Wu, Chunhui Cui, Yujing Tan   +11 more
doaj   +1 more source

LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy

International Journal of Nanomedicine
Yajuan Yan,1,* Ting Duan,1,* Xiaonan Xue,1,* Xiaojuan Yang,2 Miao Liu,2 Bin Ma,3,4 Xiangguo Duan,2 Chunxia Su1 1Department of Basic Medicine, Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2Department of Inspection ...
Yan Y, Duan T, Xue X, Yang X, Liu M, Ma B, Duan X, Su C   +7 more
doaj  

Association of TIGIT and CD155 with KRAS, NRAS, BRAF, PIK3CA, and AKT Gene Mutations, MSI Status, and Cytokine Profiles in Colorectal Cancer. [PDF]

Int J Mol Sci
Ochman B, Limanówka P, Mielcarska S, Kula A, Dawidowicz M, Hudy D, Szrot M, Piecuch J, Czuba Z, Waniczek D, Świętochowska E.   +10 more
europepmc   +1 more source

IL-22-STAT3-CD155 axis in alveolar echinococcosis: a pivotal role in immune exhaustion and therapeutic potential. [PDF]

Front Immunol
Li L, Zhang X, Yang N, Liu H, Xue J, Chu J, Lv G, Aji T, Bi X, Lin R.   +9 more
europepmc   +1 more source

Enhancing anti-tumor immunity through co-blocking PD-L1 and TIGIT by facilitating tumor-directed responses and additional VEGF inhibition. [PDF]

Front Immunol
Zhu X, Cui X, Yu H, Xu J, Chen X, Ren X, Wei X, Chen S, Wang Y, Fei L, Xie B, Li M, Li X, Jia H, Feng Y, Xia S, Chen L, Cheng Y, Zhang L, Li H, Zhu X, Zhan Y.   +21 more
europepmc   +1 more source

Immunotherapeutic strategies targeting the PVR-TIGIT/CD96/CD226 signaling pathway in glioma treatment. [PDF]

Ann Med
Qian D, Guo J, Duan Y, Zhou Y, Wu C, Chen Q, Cai J.   +6 more
europepmc   +1 more source

Blockade of CD155 and CD276 by Monoclonal Antibodies Fosters Immune Tolerance and Promotes Stable Engraftment of iPSC-Derived Islets in Allogeneic Humanized Mice. [PDF]

Transpl Int
Siracusano G, Deambrogio F, Sordi V, Malnati M, Piemonti L, Chimienti R.   +5 more
europepmc   +1 more source

CD155 density on target cells drives divergent natural killer cell responses owing to DNAM-1 loss. [PDF]

J Immunol
Saunders PM, Oates CVL, Hare R, Burgess M, Vargas Pavia TA, Worboys JD, Davis DM, Brooks AG.   +7 more
europepmc   +1 more source