Results 91 to 100 of about 98,093 (297)
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
CD16 expression is increased on monocytes of cancer patients.
, 2012 The expression level of CD16 and TIE2 on monocyte subsets was determined for healthy individuals and patients with localized or metastatic colorectal cancer. Mean fluorescence intensity (MFI) of CD16-PC5 staining was evaluated for intermediate CD14++CD16+
Christine Brostjan (137496) +10 more
core +1 more source
MicroRNA Regulation of CD16 in Human Natural Killer Cells [PDF]
, 2016 Natural killer (NK) cells are lymphocytes capable of killing virus-infected and tumor cells while leaving normal tissue unharmed. CD16 is an Fc receptor that allows NK cells to perform antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor ...
Nemer, Mary
core +1 more source
Frontiers in ImmunologyIntroductionAcute myeloid leukemia (AML) is a rare haematological cancer with poor 5-years overall survival (OS) and high relapse rate. Leukemic cells are sensitive to Natural Killer (NK) cell mediated killing.
Julia Wlosik +22 more
doaj +1 more source
BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer
Advanced Science, EarlyView.BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu +12 more
wiley +1 more source
Multi-analysis of the CD16+ CD56neg HLA-DR+ NK subset.
, 2023 (a) Multidimensional reduced map generated after opt-SNE analysis in leukocytes. In light yellow are indicated leukocytes, and MC11-A (blue), MC11-B (green) and MC11-C (red). (b) Multidimensional reduced map generated after opt-SNE analysis in leukocytes.
Esther Bernaldo-de-Quirós (12547435) +12 more
core +1 more source
PLoS ONE, 2012 ObjectiveThe expression of FcγRIIIa/CD16 may render monocytes targets for activation by IgG-containing immune complexes (IC). We investigated whether FcγRIIIa/CD16 was upregulated in rheumatoid arthritis (RA), associated with TNF production in response ...
Dawn L Cooper +9 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu +9 more
wiley +1 more source
, 2014 : Objective In various chronic inflammatory processes, both the proportion and numbers of monocyte subsets are altered. In systemic lupus erythematosus (SLE), this has not been clearly determined.
Vásquez Duque, Gloria María +2 more
core +1 more source
Alterations in Monocyte CD16 in Association with Diabetes Complications
Mediators of Inflammation, 2012 Monocytes express many cell surface markers indicative of their inflammatory and activation status. Whether these markers are affected by diabetes and its complications is not known and was investigated in this study. Blood was obtained from 22 nondiabetic and 43 diabetic subjects with a duration of diabetes >10 years, including 25 without and 18 ...
Danqing Min +8 more
openaire +3 more sources