Results 191 to 200 of about 49,899 (288)

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source

Enhanced tumor metastasis driven by the crosstalk between melanoma cells and tumor-associated macrophages: insights into the CXCL10/CXCR3-hnRNP C-MIF axis. [PDF]

J Immunother Cancer
Wang Y, Massa C, Tammineni GC, Ulagappan K, Yang B, Kokoretsis D, Zhao Y, Subbarayan K, Seliger B.   +8 more
europepmc   +1 more source

Role of CD163 in dermatology

International Journal of Dermatology, Venereology and Leprosy Sciences
Esraa El Saeed Abdulaty Sallam, Dina Magdy El Guindy, Ghada Fawzy Rezk Hassan, Iman Hamed El Maadawy   +3 more
openaire   +1 more source

A frontal lobe mass in a 6‐year‐old girl

Brain Pathology, EarlyView.
Francesca S. Vacca, Aaron Mochizuki, Smruti K. Patel, Blaise Jones, Somak Roy, Kirti Gupta   +5 more
wiley   +1 more source

Targeting a Novel AREG+ Dendritic Cell Alleviates Renal Fibrosis Induced by Ischemia–Reperfusion Injury

Cell Proliferation, EarlyView.
Renal IRI induces tubular EMT and fibrosis. CD11c+AREG+ DCs mediate the process via AREG‐EGFR axis, serving as promising therapeutic targets. ABSTRACT Renal ischemia–reperfusion injury (RIRI) is a major cause of acute tubular damage and a key driver of maladaptive repair and fibrosis.
Xin Luo, Longbin Xiong, Zhaohui Zhou, Lihao Zhang, Yulu Peng, Xiangpeng Zou, Yixin Huang, Yisong Lin, Xiaofeng Yang, Zhanji Zhan, Fangjian Zhou, Youhua Liu, Chunping Yu, Baokui Ye, Zhiling Zhang   +14 more
wiley   +1 more source

Immune- and Stromal-Associated Tissue-Context Profiles in Pretreatment Triple-Negative Breast Cancer: An Exploratory Institutional Cohort Study. [PDF]

Diseases
Zuccalà V, Staropoli N, Labanca C, Ricciardi G, Tralongo P, Fiorentino V, Procopio E, Renne M, Ieni A, Martini M, Tassone P, Tagliaferri P.   +11 more
europepmc   +1 more source

Solitary Indeterminate Cell Histiocytosis Presenting as a Reddish Nodule on the Abdomen of a 4‐Year‐Old Boy: Clinicopathologic Correlation and Electron Microscopy Findings

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Indeterminate cell histiocytosis (ICH) is a clonal proliferative disorder of mononuclear phagocyte cells that shows features of both dendritic and histiocytic cells. Only around 100 cases of ICH were reported, and among them, only 24% of reported cases involve pediatric patients, with a mean age at diagnosis of 50 years.
Seung‐Soo Lee, Seok‐Jong Lee, Weon Ju Lee, Dae‐Lyong Ha   +3 more
wiley   +1 more source

Tissue Factor Expression Is Associated with Distinct Pattern of Immune-Cell Infiltration in the Ovarian Tumor Microenvironment. [PDF]

Int J Mol Sci
Mohiuddin TM, Binte Hafiz F, Sheng W, Zhang C, Al-Rawe M, Zeppernick F, Tchaikovski S, Meinhold-Heerlein I, Hussain AF.   +8 more
europepmc   +1 more source

Cross-Species Reactivity and Differential Anti-PRRSV Activities of CD163 SRCR4/SRCR5 Monoclonal Antibodies. [PDF]

Vet Sci
Meng Y, Yang S, Jiao J, Zhang P, Guan Q, Lin Y, Cui M, Wang X, Zhu X, Qiu M, Lin H, Zheng W, Zhu J, Stoian AMM, Fraile L, Chen N.   +15 more
europepmc   +1 more source

New insights into β‐cell vulnerability in type 1 diabetes—Lessons from nature

Diabetic Medicine, EarlyView.
Abstract Type 1 diabetes results from an autoimmune‐mediated destruction of pancreatic β‐cells, yet considerable heterogeneity exists regarding disease onset, progression and severity. Emerging evidence suggests that this variability reflects not only differences in immune responses, but also differences in the architecture and immune landscape of the ...
Kathryn Murrall, Teifion Luckett, Christiana Lekka, Stephanie L. Hunter, Sylvie Agnello, Peter Ferris, Emma Haxton, Christine S. Flaxman, Abirami Kannan, Xinpeng Dun, Sarah J. Richardson   +10 more
wiley   +1 more source