Results 171 to 180 of about 49,329 (202)

Soluble CD163

Scandinavian Journal of Clinical and Laboratory Investigation, 2011
CD163 is an endocytic receptor for haptoglobin-hemoglobin complexes and is expressed solely on macrophages and monocytes. As a result of ectodomain shedding, the extracellular portion of CD163 circulates in blood as a soluble protein (sCD163) at 0.7-3.9 mg/l in healthy individuals.
openaire   +3 more sources

CD163+ Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma

Circulation Research
BACKGROUND: Cell phenotype switching is increasingly being recognized in atherosclerosis. However, our understanding of the exact stimuli for such cellular transformations and their significance for human atherosclerosis is still evolving.
M. Mori, Atsushi Sakamoto, Rika Kawakami, Liang Guo, L. Slenders, J. Mosquera, S. Ghosh, M. Wesseling, T. Shiraki, Arielle Bellissard, Palak Shah, C. Weinkauf, Takao Konishi, Y. Sato, A. Cornelissen, K. Kawai, H. Jinnouchi, Weili Xu, Aimee E. Vozenilek, Desiree Williams, Takamasa Tanaka, T. Sekimoto, Michael C. Kelly, Raquel Fernandez, Alyssa Grogan, A.J. Coslet, Alisa Fedotova, Anjali Kurse, Michal Mokry, Maria E. Romero, F. Kolodgie, Gerard Pasterkamp, C. Miller, R. Virmani, A. Finn   +34 more
semanticscholar   +1 more source

The significance of CD163-expressing macrophages in asthma

Annals of Allergy, Asthma & Immunology, 2019
CD163 is one of the scavenger receptors that are specifically expressed on macrophages and are well known to be upregulated by various inflammatory responses, including chronic obstructive pulmonary disease in airway diseases.To evaluate the CD163 expression in the lungs of patients with fatal asthma and investigated whether CD163 contributes to the ...
Yoshihisa, Tokunaga, Haruki, Imaoka, Yoichiro, Kaku, Tomotaka, Kawayama, Tomoaki, Hoshino   +4 more
openaire   +2 more sources

Mechanistic Insights into PRRSV Inhibition through CD163–SRCR5 Blockade by PRRSV/CD163-IN-1

The Journal of Physical Chemistry Letters
Porcine reproductive and respiratory syndrome virus (PRRSV) causes severe economic losses in the swine industry by targeting pulmonary alveolar macrophages via the CD163 receptor, particularly its SRCR5 domain. However, the molecular details of small-molecule inhibition at this interface remain unclear.
Prawit Thitayanuwat, Kowit Hengphasatporn, Surang Chankhamhaengdecha, Yasuteru Shigeta   +3 more
openaire   +2 more sources

CD163 is not a sensitive marker for identification of atypical fibroxanthoma

Journal of Cutaneous Pathology, 2011
The histopathological features of atypical fibroxanthoma (AFX) overlap with those of poorly differentiated carcinoma, melanoma and leiomyosarcoma in the skin. As there are no specific stains to identify AFX, the diagnosis is essentially one of exclusion and requires completion of a panel of immunostains.
openaire   +2 more sources

CD163‐positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma

Pathology International, 2021
Yoichi Saito, Yukio Fujiwara, Yae Kanai   +2 more
exaly  

CD163

1997
A. Neil Barclay, Marion H. Brown, S.K. Alex Law, Andrew J. McKnight, Michael G. Tomlinson, P. Anton van der Merwe   +5 more
openaire   +1 more source

Neuron derived fractalkine promotes microglia to absorb hematoma via CD163/HO-1 after intracerebral hemorrhage

Cellular and Molecular Life Sciences, 2022
Mingfeng You, Chunnan Long, Yan Wan, Hongxiu Guo, Jing Shen, Man Li, Quanwei He, Bo Hu   +7 more
semanticscholar   +1 more source

CD163+ and CD14+ macrophages are increased in obese children

Journal of Pediatric Endocrinology and Metabolism, 2023
Nikita S. Denisov, Lyudmila V. Spirina, Iuliia G. Samoilova, Ekaterina M. Kamenskih, Ksenya A. Chubakova, Daria A. Sitnikova, Dmitry A. Svarovsky   +6 more
openaire   +2 more sources

Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163

Journal of Controlled Release, 2012
Jonas Heilskov Graversen, Holger Jon Møller, Anders Etzerodt   +2 more
exaly