Immune landscape characterization of neurofibromas with atypical features in Neurofibromatosis1 reveals PD-1 and the Tim-3/Galectin-9 pathway as potential therapeutic targets. [PDF]
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Local immunosuppressive microenvironment underlies reduced responsiveness to imiquimod treatment in recurrent or residual cervical HSIL. [PDF]
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Dyslipidemia is associated with monocyte lipid metabolic reprogramming in Guillain-Barré syndrome. [PDF]
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The mechanism of PKM2/HIF-1α axis polarizing TAMs by upregulating glucose-serine metabolism to promote melanoma progression. [PDF]
Yang Y +10 more
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Assignment of the CD163 antigen (CD163) to mouse chromosome 6 band F2 by radiation hybrid mapping.
Schaer DJ, Schoedon G, Schaffner A
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The Clinical Utility of CD163 in Viral Diseases.
Clinica Chimica Acta, 2023Macrophage activation and hypercytokinemia are notable presentations in certain viral infections leading to severe disease and poor prognosis. Viral infections can cause macrophage polarization into the pro-inflammatory M1 or anti-inflammatory M2 ...
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The macrophage scavenger receptor CD163
Mature tissue macrophages form a first line of defense to recognize and eliminate potential pathogens; these specialized cells are capable of phagocytosis, degradation of self and foreign materials, establishment of cell-cell interactions, and the production of inflammatory mediators.
Timo Van Den Berg, Christine D Dijkstra
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Targeted delivery of small extracellular vesicles (sEVs) with low immunogenicity and fewer undesirable side effects are needed for spinal cord injury (SCI) therapy. Here, we show that RGD (Arg-Gly-Asp) peptide-decorated CD163+ macrophage-derived sEVs can
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Transcript levels of cytokines and SERPINA3 have been used to define a substantial subset (40%) of individuals with schizophrenia with elevated inflammation and worse neuropathology in the dorsolateral prefrontal cortex (DLPFC).
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Biological variation of soluble CD163
Scandinavian Journal of Clinical and Laboratory Investigation, 2003A soluble plasma form of CD163 (sCD163) was recently identified. The protein has anti-inflammatory effects in vitro and is elevated in patients with myelo-monocytic leukaemia and infection. For rational use and evaluation of this potential new quantity it is important to have knowledge of its biological variability and to use a methodology that has a ...
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