Results 141 to 150 of about 49,899 (288)

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection

Frontiers in Oncology
ObjectiveThis study investigated the association between Helicobacter pylori (H. pylori) infection and the expression of CD163+ and CD86+ tumor-associated macrophages (TAMs) in colorectal adenoma (CRA) and colorectal cancer (CRC) tissues ...
Wenming Wang, Wenming Wang, Yueyong Zhu, Yunchao Zhu, Jin Wang   +4 more
doaj   +1 more source

Kaplan-Meier survival analysis with log-rank test according to combinatory statuses of CD8+ or FoxP3+ TILs and CD163+ TAMs.

, 2016
(a) Survival curves of the low density (n = 70) vs. high density (n = 73) groups of CD8+ TILs in IF. (b) Survival curves of the low density (n = 72) vs. high density (n = 71) groups of FoxP3+ TILs in IF.
Han Kwang Yang (841405), Kyung-Ju Kim (841403), Xian-Yu Wen (841404), Woo Ho Kim (70175), Gyeong Hoon Kang (177142)   +4 more
core   +1 more source

Hyperbranched poly‐L‐lysine surface‐engineered bioprosthetic heart valves with anti‐calcification, anti‐infection, and durability

BMEMat, EarlyView.
The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng, Dongchao Qiu, Yongyuan Kang, Qiaoxuan Wang, Xuelong Wang, Boyana Parvanova, Miroslav Karabaliev, Changyou Gao   +7 more
wiley   +1 more source

Nanoagonist‐mediated spatiotemporal reprogramming of macrophage phenotypes to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang, Fengfeng Xiao, Ruie Chen, Cuixia Lu, Yi Ju, Mingqing Yuan, Yunlu Dai, Liewei Wen   +7 more
wiley   +1 more source

Calcium-dependent oligomerization of scavenger receptor CD163 facilitates the endocytosis of ligands

Nature Communications
Scavenger receptor CD163 is a marker of M2 type macrophages that play important roles in anti-inflammatory processes. The most extensively studied function of CD163 is related to the elimination of hemoglobin-haptoglobin (Hb-Hp) complexes, to prevent ...
Hua Xu, Xiaohui Song, Xiao-dong Su
doaj   +1 more source

CD163-L1 Is an Endocytic Macrophage Protein Strongly Regulated by Mediators in the Inflammatory Response

, 2012
CD163-L1 belongs to the group B scavenger receptor cysteine-rich family of proteins, where the CD163-L1 gene arose by duplication of the gene encoding the hemoglobin scavenger receptor CD163 in late evolution.
Moestrup, Søren, Nielsen, Ole, Nielsen, Marianne J, Reichhardt, Martin P, Schlosser, Anders, Moeller, Jesper B, Sørensen, Grith Lykke; id_orcid, Tornøe, Ida, Jensen, Ole Nørregaard; id_orcid, Grønlund, Jørn, Holmskov, Uffe, Nielsen, Maria E, Mollenhauer, Jan, Jørgensen, Jan S   +13 more
core   +1 more source

Small scale purification and biophysical characterization of haptoglobin derived from human Cohn fraction IV

Biotechnology Progress, EarlyView.
Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu, Mohd Asim Khan, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +5 more
wiley   +1 more source

NOS2 and CD163 immunoreactivity in patient samples.

, 2013
Representative light microscopic images of immunohistochemical stainings of NOS2 and CD163 in consecutive sections of the same CRC tumor sample.
Anna M. Dahlin (208318), Per-Arne Oldenborg (132461), Sofia Edin (208320), Jörgen Rutegård (302813), Åke Öberg (208327), Richard Palmqvist (156586), Maria L. Wikberg (302811)   +6 more
core   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath, Azfar Neyaz, Samer Khader   +2 more
wiley   +1 more source