Results 51 to 60 of about 49,329 (202)

Macrophage Densities Correlated with CXC Chemokine Receptor 4 Expression and Related with Poor Survival in Anaplastic Thyroid Cancer [PDF]

Endocrinology and Metabolism, 2016
BackgroundTumor associated macrophages (TAMs) and CXC chemokine receptor 4 (CXCR4) have emerged as potential biomarkers in various human cancers. The aims of this study were to investigate the clinical characteristics of anaplastic thyroid cancer (ATC ...
Dae In Kim, Eunyoung Kim, Young A Kim, Sun Wook Cho, Jung Ah Lim, Young Joo Park   +5 more
doaj   +1 more source

CD163 and Inflammation: Biological, Diagnostic, and Therapeutic Aspects [PDF]

Antioxidants & Redox Signaling, 2013
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.
Etzerodt, Anders; id_orcid 0000-0002-6757-2068, Moestrup, Søren Kragh   +1 more
openaire   +3 more sources

Soluble CD163 and CD163 Expression on Monocytes Associated with Chronic Hepatitis B Inflammation and HBsAg Loss

Journal of Clinical and Translational Hepatology, 2022
Monocyte/macrophage-associated CD163 is an indicator of the severity of liver inflammation and cirrhosis, but the difference of soluble CD163 (sCD163) levels in chronic hepatitis B (CHB) patients and hepatitis B surface antigen (HBsAg)-loss patients is unclear.
Peilin Xie, Bilian Yao, Dao Huang, Yongyan Chen, Qiming Gong, Xinxin Zhang   +5 more
openaire   +2 more sources

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis [PDF]

Arthritis & Rheumatism, 2004
AbstractObjectiveSince CD163+ macrophages are selectively increased in spondylarthropathy (SpA) synovitis, we investigated the role of CD163+ macrophages in synovial inflammation.MethodsSynovial biopsy samples from 26 SpA and 23 rheumatoid arthritis (RA) patients were analyzed for macrophage and lymphocyte subsets.
Baeten, D., Møller, H.J., Delanghe, J., Veys, E.M., Moestrup, S.K., Keyser, F.De   +5 more
openaire   +3 more sources

Soluble CD163 Levels and CD163+CD14+ Monocyte/Macrophage Counts in Patients with Asthma.

Iranian journal of immunology : IJI, 2018
CD163-expressing macrophages are involved in the inflammatory response in asthma.To assess sputum and serum soluble CD163 (sCD163) and cytokine levels in patients with asthma. Further discussed was the difference between sCD163 and other classic inflammatory mediators.Sputum was successfully induced in asthma patients (n=85) and healthy controls (n=21).
Zhi, Yue, Gao, Peng, Li, Wei, Zhang, Jie, Gao, Fengling, Zhang, Jichun, Lin, Haitao   +6 more
openaire   +3 more sources

Prognostic value of CD163+ macrophages in solid tumor malignancies: A scoping review.

Immunology Letters
Tumor-associated macrophages (TAMs) play crucial roles in development and progression of malignant diseases. Notably, CD163+ TAMs likely perform specific pro-tumorigenic functions, suggesting that this subset may serve as both prognostic biomarkers and ...
Henriette Mathiesen, Kristian Juul-Madsen, T. Tramm, T. Vorup-Jensen, Holger Jon Møller, A. Etzerodt, M. N. Andersen   +6 more
semanticscholar   +1 more source

Adaptation of African swine fever virus to porcine kidney cells stably expressing CD163 and Siglec1

Frontiers in Immunology, 2022
African swine fever virus (ASFV) is a complex large DNA enveloped virus that causes African swine fever (ASF) with a fatality rate of up to 100%, seriously threatening the global swine industry.
Qi Gao, Yunlong Yang, Yizhuo Luo, Jiachen Zheng, L. Gong, Heng Wang, Yongzhi Feng, Ting Gong, Dongdong Wu, Rui-xia Wu, Xiaoyuan Zheng, Zezhong Zheng, Guihong Zhang   +12 more
semanticscholar   +1 more source

Prognostic Implications of Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis

Journal of Orofacial Sciences
Introduction: Tumor-associated macrophages (TAMs) are the major cellular component in the tumor microenvironment of oral squamous cell carcinoma (OSCC). Several studies have been put forward to assess the role of TAMs in the prognostication of OSCC.
Surya Surendran L, Anna Palliath Joseph, Varun B Raghavan Pillai, Vinej Somaraj, Sunjith Sudhakar, Amitha Mohan   +5 more
doaj   +1 more source

Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells

Immunity, 2020
Summary Dendritic cells (DCs) are antigen-presenting cells controlling T cell activation. In humans, the diversity, ontogeny, and functional capabilities of DC subsets are not fully understood. Here, we identified circulating CD88−CD1c+CD163+ DCs (called
Pierre Bourdely, G. Anselmi, K. Vaivode, R. Ramos, Y. Missolo-Koussou, Sofía Hidalgo, Jimena Tosselo, N. Núñez, W. Richer, A. Vincent‐Salomon, A. Saxena, Kristie Wood, Á. Lladser, E. Piaggio, J. Helft, P. Guermonprez   +15 more
semanticscholar   +1 more source

Structural elucidation of the haptoglobin–hemoglobin clearance mechanism by macrophage scavenger receptor CD163

bioRxiv
Intravascular hemolysis releases hemoglobin into the bloodstream, which can damage vascular and renal tissues due to its oxidative nature. Circulating haptoglobin acts as a primary defense by binding to free hemoglobin, forming a haptoglobin-hemoglobin ...
Ching-Shin Huang, Hui Wang, Joshua B. R. White, O. Degtjarik, Cindy Huynh, Kristoffer Brannstrom, Mark T. Horn, Stephen P. Muench, W. Somers, Javier Chaparro-Riggers, Laura Lin, Lidia Mosyak   +11 more
semanticscholar   +1 more source