Results 61 to 70 of about 48,020 (257)

Association of CD163+ macrophages and local production of soluble CD163 with decreased lymphocyte activation in spondylarthropathy synovitis

, 2004
OBJECTIVE: Since CD163+ macrophages are selectively increased in spondylarthropathy (SpA) synovitis, we investigated the role of CD163+ macrophages in synovial inflammation.
Baeten, Dominique, MOESTRUP, SK, Møller, Holger Jon, Moestrup, Søren K., DELANGHE, J, Veys, Eric M., MOLLER, HJ, Veys, Eric, De Keyser, Filip, Delanghe, Joris   +9 more
core   +1 more source

CD163ΔSRCR5 MARC-145 Cells Resist PRRSV-2 Infection via Inhibiting Virus Uncoating, Which Requires the Interaction of CD163 With Calpain 1

Frontiers in Microbiology, 2020
Porcine alveolar macrophages without the CD163 SRCR5 domain are resistant to porcine reproductive and respiratory syndrome virus (PRRSV) infection. However, whether the deletion of CD163 SRCR5 in MARC-145 cells confers resistance to PRRSV and interaction
Piao Yu, Ruiping Wei, Wenjuan Dong, Zhenbang Zhu, Xiaoxiao Zhang, Yaosheng Chen, Xiaohong Liu, Chunhe Guo   +7 more
doaj   +1 more source

A Case of a 40‐year‐old Female with Speech Disturbance

Annals of Clinical and Translational Neurology, EarlyView.
Victoria Lorah, Michael V. Robers
wiley   +1 more source

Dual Blockade of LILRB1 and LILRB2 Enhances Antiviral Immune Responses in SIV Infection

Advanced Science, EarlyView.
Dual LILRB1/B2 blockade with mac20G10 reshapes myeloid activation during acute SIV infection by targeting LILRB1 and LILRB2 on myeloid cells. This treatment enhances CD80 expression on selected myeloid subsets and increases plasma IFN‐λ, IL‐8, and IL‐1RA.
Florian Meurisse, Sixtine Coindre, Anne Wijkhuisen, Romain Marlin, Laure Fournier Le Ray, Juliette Pons, Melyssa Yaugel‐Novoa, Véronique Avettand‐Fenoel, Laurent Abi‐Rached, Anne‐Sophie Gallouet, Francis Relouzat, Mael Gourves, Asier Saez‐Cirion, Hisashi Arase, Gerard Zurawski, Sandra Zurawski, Nathalie Dereuddre‐Bosquet, Roger Le Grand, Stéphanie Simon, Olivier Lambotte, Benoit Favier   +20 more
wiley   +1 more source

CD163 protein expression is increased in IBD.

, 2013
A. Representative Western blots showing CD163 and β actin in total proteins extracted from mucosal samples of 2 CTR, 2 UC patients and 2 CD patients. Right panel shows the quantitative analysis of CD163/β-actin ratio in mucosal samples taken from 8 CTR ...
Roberta Caruso (438408), Alfredo Colantoni (438413), Livia Biancone (288349), Daniela De Nitto (438412), Ivan Monteleone (288334), Francesco Pallone (288353), Maria Laura Cupi (438410), Francesca Zorzi (288332), Giovanni Monteleone (288355), Flavio Caprioli (438411), Massimiliano Sarra (288336), Carmine Stolfi (438409), Eleonora Franzè (438407)   +12 more
core   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Cell surface expression of CD163 in THP-1 cells.

, 2014
(A) Representative histograms of CD14 and CD163 expression. (B) Quantification of mean fluorescence intensity of CD163 and CD14 expression. (C) Quantification of percentages of CD163+/CD14+ cells and CD163−/CD14+ cells.
Hiromichi Takahashi (663363), Yuichiro Hasegawa (663366), Hikaru Uchida (663367), Noriyoshi Iriyama (663365), Masaru Nakagawa (663368), Makoto Makishima (294803), Yoshihiro Hatta (663364), Masami Takei (200276), Jin Takeuchi (200338)   +8 more
core   +1 more source

Hypomethylation of GNA15 Promotes Pancreatic Ductal Adenocarcinoma Progression and Macrophage M2 Polarization via STAT3‐CXCL8 Axis

Advanced Science, EarlyView.
A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo, Zhenyuan Qian, Lei Wang, Weilang Xu, Yuxin Weng, Kai Jiang, Zaiyuan Ye, Ji Xu, Guangyuan Song   +8 more
wiley   +1 more source