Results 81 to 90 of about 49,329 (202)

The Diagnostic Significance of CXCL13 in M2 Tumor Immune Microenvironment of Human Astrocytoma

Pathology and Oncology Research, 2022
Background: CXCL13 may act as a mediator of tumor-associated macrophage immunity during malignant progression.Objective: The present study clarifies the clinicopathological significances of CXCL13 and its corresponding trend with M2 macrophage in human ...
Shu-Jyuan Chang, Shu-Jyuan Chang, Chia-Te Chao, Aij-Lie Kwan, Aij-Lie Kwan, Chee-Yin Chai, Chee-Yin Chai, Chee-Yin Chai   +7 more
doaj   +1 more source

Hemoglobin scavenger receptor CD163 as a potential biomarker of hemolysis-induced hepatobiliary injury in sickle cell disease

American Journal of Physiology - Cell Physiology
Sickle cell disease (SCD) associated chronic hemolysis promotes oxidative stress, inflammation and thrombosis leading to organ damage, including liver damage.
T. Kaminski, Ayyanar Sivanantham, Anna Mozhenkova, Ashley Smith, Ramakrishna Ungalara, R. Dubey, Bibhav Shrestha, Corrine B Hanway, O. Katoch, Jesús Tejero, P. Sundd, Enrico M. Novelli, Gregory J. Kato, T. Pradhan‐Sundd   +13 more
semanticscholar   +1 more source

CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance

eLife, 2020
Porcine reproductive and respiratory syndrome virus (PRRSV) and transmissible gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major economic losses to pig production.
Kui Xu, Yanrong Zhou, Y. Mu, Zhiguo Liu, Shaohua Hou, Yujian Xiong, L. Fang, Changli Ge, Yinghui Wei, Xiu-Hang Zhang, Changjiang Xu, Jingjing Che, Ziyao Fan, Guangming Xiang, Jiankang Guo, Haitao Shang, Hua Li, Shaobo Xiao, Julang Li, Kui-Lin Li   +19 more
semanticscholar   +1 more source

High Infiltration of CD68+/CD163− Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma

Journal of Innate Immunity, 2022
Tumor-associated macrophages (TAMs) have emerged as key players in tumor immunology but demonstrate a continuum of functional states being either tumor suppressive or promoting.
Maria C. Svensson, Maja Svensson, B. Nodin, D. Borg, C. Hedner, C. Hjalmarsson, K. Leandersson, K. Jirström   +7 more
semanticscholar   +1 more source

Soluble CD163 as a Potential Biomarker in Systemic Sclerosis [PDF]

Disease Markers, 2018
Objective. To evaluate the performance of serum and urinary sCD163 concentrations as possible biomarker in systemic sclerosis (SSc). Methods. Urine and serum samples were obtained from SSc patients and age- and sex-matched controls. Serum and urinary sCD163 concentrations were measured by commercially available ELISA kit.
Frantz, Camelia, Pezet, Sonia, Avouac, Jerome, Allanore, Yannick   +3 more
openaire   +2 more sources

Evaluation of urinary CD163 level as a biomarker for the diagnosis of lupus nephritis

Медицинская иммунология
Aim of the work: to evaluate urinary CD163 as a possible biomarker indicating activity of lupus nephritis (LN). This retrospective, cross-sectional study evaluated 68 patients diagnosed with systemic lupus erythematosus (SLE) over a year, focusing on ...
Samar Ahmed Eissa, Rabab Alaa Eldin Keshk, Hebatalla Abd Elmaksoud Ahmed, Sally Ali Saleh   +3 more
doaj   +1 more source

Recent advances in inhibition of porcine reproductive and respiratory syndrome virus through targeting CD163

Frontiers in Microbiology, 2022
Porcine reproductive and respiratory syndrome virus (PRRSV) has plagued the pig industry for more than 30 years and causes great economic losses. At present different commercial vaccines are available but limited tools.
Xiaoxiao Zhang, Chunhe Guo
semanticscholar   +1 more source

Scavenger Receptor CD163 and Its Biological Functions [PDF]

Acta Medica (Hradec Kralove, Czech Republic), 2009
CD163 is a member of scavenger receptor super family class B of the first subgroup. It is mapped to the region p13 on chromosome 12. Five different isoforms of CD163 have been described, which differ in the structure of their cytoplasmic domains and putative phosporylation sites.
Gabriela Onofre, Martina Koláčková, Karolína Jankovičová, Jan Krejsek   +3 more
openaire   +3 more sources

Characterisation of Macrophage Sub-populations in Oral Lichen Planus using CD64 and CD163 – An Evaluative Study

Indian Journal of Dental Research
Background: Oral lichen planus (OLP) stands out as one of the prevalent chronic inflammatory conditions affecting the oral cavity, with its aetiology linked to immune-mediated processes.
L Surya Surendran, Anna P. Joseph, Varun B. Raghavan Pillai, Freeda Mary Selvaraj   +3 more
doaj   +1 more source

Deficiency of the hemoglobin-haptoglobin receptor, CD163, worsens insulin sensitivity in obese male mice

bioRxiv
Excessive iron accumulation in metabolic organs such as the adipose tissue, liver, and skeletal muscle is associated with increased diabetes risk. Tissue-resident macrophages serve multiple roles including managing inflammatory tone and regulating ...
Michael W. Schleh, Magdalene K. Ameka, Alec S. Rodriguez, Alyssa H. Hasty   +3 more
semanticscholar   +1 more source