Results 101 to 110 of about 49,329 (202)

CD163 deficiency facilitates lipopolysaccharide‐induced inflammatory responses and endotoxin shock in mice

Clinical & Translational Immunology, 2020
Objectives Septic (or endotoxin) shock is a severe systemic inflammatory disease caused by bacteraemia or endotoxaemia. Although it is known that increased serum levels of CD163 are observed in septic/endotoxin shock patients, the exact function and ...
Yukio Fujiwara, Koji Ohnishi, Hasita Horlad, Yoichi Saito, Daisuke Shiraishi, Hiroto Takeya, Daiki Yoshii, Shinjiro Kaieda, Tomoaki Hoshino, Yoshihiro Komohara   +9 more
doaj   +1 more source

HOXA9 and CD163 potentiate pancreatic ductal adenocarcinoma progression

Diagnostic Pathology
Background The role of HOXA9 requires investigations in pancreatic ductal adenocarcinoma (PDAC) as HOXA9 inhibitors are being developed. HOXA9 might attract CD163 expressed tumor associated macrophages (TAM) and could affect PDAC prognosis.
Aiat Shaban Hemida, Mohamed Mohamady Ahmed, Mona Saeed Tantawy   +2 more
doaj   +1 more source

Evaluation of soluble CD163 as a marker of inflammation in psoriasis

Clinical and Experimental Dermatology, 2011
Summary A reliable biomarker of disease activity in psoriasis would be helpful for management, especially if this gave early information on treatment efficacy. This study investigated whether serum levels of soluble (s)CD163 correlated with psoriasis activity as assessed by the Psoriasis Area and Severity Index (PASI).
C, Feighery, J, Dunne, E A, Bingham, C F, Feighery   +3 more
openaire   +2 more sources

Tumor Microenvironment Modulation by Tumor-Associated Macrophages: Implications for Neoadjuvant Chemotherapy Response in Breast Cancer

Breast Cancer: Targets and Therapy
Gizem Oner,1– 3 Marleen Marguerite Praet,4 Hans Stoop,4 Gayathri R Devi,5 Nuh Zafer Canturk,3 Sevilay Altintas,1,2 Christophe Van Berckelaer,1,2 Zwi Berneman,6 Wiebren Tjalma,1,2 Senada Koljenovic,4 Peter A van Dam1,2 1Multidisciplinary Oncologic Centre ...
Oner G, Praet MM, Stoop H, Devi GR, Canturk NZ, Altintas S, Van Berckelaer C, Berneman Z, Tjalma W, Koljenovic S, van Dam PA   +10 more
doaj  

Sialoadhesin-dependent susceptibility and replication of porcine reproductive and respiratory syndrome viruses in CD163-expressing cells

Frontiers in Veterinary Science
Understanding the molecular interactions between porcine reproductive and respiratory syndrome viruses (PRRSVs) and host cells is crucial for developing effective strategies against PRRSV.
Hyun-Ji Lee, Su-Hwa You, Hyang-Sim Lee, Yeun-Kyung Shin, Yun Sang Cho, Tae-Sub Park, Seok-Jin Kang   +6 more
doaj   +1 more source

Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma.

PLoS ONE, 2015
Tumor associated macrophages are major inflammatory cells that play an important role in the tumor microenvironment. In this study, we investigated the prognostic significance of tumor associated macrophages (TAMs) in MSI-high gastric cancers using ...
Kyung-Ju Kim, Xian-Yu Wen, Han Kwang Yang, Woo Ho Kim, Gyeong Hoon Kang   +4 more
doaj   +1 more source

Cloning and expression of porcine CD163 Its use for characterization of monoclonal antibodies to porcine CD163 and development of an ELISA to measure soluble CD163 in biological fluids

, 2023
Peer ...
Pérez, Carlos, Ortuño, E., Gómez, Nuria, García-Briones, M. M., Álvarez, Belén, Martínez De la Riva, Paloma, Alonso, Frank, Revilla Calvo, Concepción, Domínguez, Javier, Ezquerra Martínez, Ángel   +9 more
openaire   +1 more source

Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship to Helicobacter pylori infection

Frontiers in Oncology
ObjectiveThis study investigated the association between Helicobacter pylori (H. pylori) infection and the expression of CD163+ and CD86+ tumor-associated macrophages (TAMs) in colorectal adenoma (CRA) and colorectal cancer (CRC) tissues ...
Wenming Wang, Wenming Wang, Yueyong Zhu, Yunchao Zhu, Jin Wang   +4 more
doaj   +1 more source

Pigs with CD163 Mutation Conferred PRRSV Resistance [PDF]

Animals (Basel)
Porcine reproductive and respiratory syndrome (PRRS), which is caused by the porcine reproductive and respiratory syndrome virus (PRRSV), results in substantial economic losses for the global pig farming industry. A critical step in the infection process is the binding of PRRSV to the CD163 receptor on the surface of porcine alveolar macrophages.
Wu C, Wang H, Zhang W, Cheng M, Wang Y, Chen L, Tang C, Dai Y, Zhang L.   +8 more
europepmc   +4 more sources

Reduced Membrane CD163 Expression in 7-Oxysterol-Induced Apoptosis Accompanied by Elevated Oxidative Stress

Cells
CD163 is a transmembrane scavenger receptor predominantly expressed by activated M2-like macrophages and is involved in inflammatory processes. Oxysterols, which accumulate in atherosclerotic lesions, are known to induce oxidative stress and apoptosis in
Wei Li, Xi-Ming Yuan
doaj   +1 more source