Results 91 to 100 of about 49,899 (288)

Is CD163 - A Marker of Progression in Osteoarthritis?

Journal of Kermanshah University of Medical Sciences, 2018
Background: CD163 is a cell surface glycoprotein as known as a hemoglobin/haptoglobin scavenger receptor. The Soluble form of CD163 attenuates macrophages immune response. Objectives: The aim of this study is to describe the effect of CD 163 phagocytes on progression and joint destruction by osteoarthritis (OA). Methods: Twenty OA patients participated
Keykhosro Mardanpour, Mahtab Rahbar, Nyosha Mardanpour   +2 more
openaire   +2 more sources

CD163 Is Required for Protumoral Activation of Macrophages in Human and Murine Sarcoma

, 2018
Recent findings have shown the significance of CD163-positive macrophages in tumor progression, yet there have been few studies on the function of CD163 in macrophages.
Yoichi Saito, Yasuharu Nakashima, Hasita Horlad, Hirofumi Bekki, Toyohisa Iriki, Pan Cheng, Junko Tsuboki, Daisuke Shiraishi, Yukio Fujiwara, Motohiro Takeya, Hiroshi Mizuta, Naomi Nakagata, Yoshinao Oda, Yoshihiro Komohara   +13 more
core   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Cloning and expression of porcine CD163: its use for characterization of monoclonal antibodies to porcine CD163 and development of an ELISA to measure soluble CD163 in biological fluids

Spanish Journal of Agricultural Research, 2008
CD163 is a member of the family of proteins with scavenger receptor cysteine-rich domains, whose expression is restricted to monocytes and macrophages. It functions as a receptor for haemoglobin/haptoglobin complexes and it has also been implicated in the regulation of inflammatory processes.
Pérez, C., Ezquerra, A., Ortuño, E., Gómez, N., García-Briones, M., Martínez de la Riva, P., Alonso, F., Revilla, C., Domínguez, J.   +8 more
openaire   +3 more sources

Pie charts showing the kind of macrophage polarization in pediatric classical Hodgkin lymphoma, considering CD68 (A) or CD163 (C) as macrophage markers.

, 2015
Box-plot graphs show the numerical distribution of CD68+pSTAT1+, CD68+pSTAT1-, CD68+CMAF+ and CD68+CMAF- cells/mm2 (B), as well as CD163+pSTAT1+, CD163+pSTAT1-, CD163+CMAF+ and CD163+CMAF- cells/mm2 (D).
Priscilla Segges (739734), Gerald Niedobitek (26442), Mário H. M. Barros (132399), Rocio Hassan (132411), Gabriela Vera-Lozada (739735)   +4 more
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Prognostic and Predictive Value of CD163+ Macrophages for Neoadjuvant Chemotherapy in Osteosarcoma

Biomedicines
Background: The CD163+ macrophage is considered a key component of the tumor immune microenvironment (TIME) in osteosarcoma (OS) in relation to tumor progression and chemotherapy resistance.
Yuejun Luo, Bo Wang, Wanjiang Feng, Zibo Xu, Hongyu Wu, Ziming Yan, Haoyu Guo, Weifeng Liu   +7 more
doaj   +1 more source

CD163 Expression in Neurons After Experimental Intracerebral Hemorrhage

, 2017
Background and Purpose— CD163, a receptor for hemoglobin, is involved in hemoglobin clearance after intracerebral hemorrhage (ICH).
Guohua Xi, Ran Liu, Ya Hua, Richard F. Keep, Yining Huang, Shenglong Cao   +5 more
core   +1 more source

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang, Shuangyue Pan, Lu Bai, Bin Li, Tiantian Liu, Jianing Cao, Mengdi Yang, Heda Zhang, Duancheng Guo, Wenxiang Zhi, Zhonghua Tao, Xichun Hu   +11 more
wiley   +1 more source

Identification and Functional Analysis of EPOR+ Tumor-Associated Macrophages in Human Osteosarcoma Lung Metastasis

Journal of Immunology Research, 2020
Background. Tissue-resident macrophages can be educated to tumor-associated macrophages (TAMs) by the tumor microenvironment and many types of macrophages express erythropoietic receptor (EPOR); However, little is known about the expression of EPOR on ...
Yanxing Li, Ming Li, Rong Wei, Junlong Wu   +3 more
doaj   +1 more source