Results 31 to 40 of about 134,446 (292)

Purification and Immunophenotypic Characterization of Human CD19+CD24hiCD38hi and CD19+CD24hiCD27+ B Cells [PDF]

, 2021
Regulatory B cells (Bregs) have immunosuppressive capacity, primarily via the production of IL-10. IL-10 expression and immunosuppression have been described in a number of human B cell subsets, two of which include the CD19+CD24hiCD38hi and CD19+CD24hiCD27+ populations.
Bradford, HF, Mauri, C
openaire   +3 more sources

Perspectives of Fc engineered antibodies in CD19 targeting immunotherapies in pediatric B-cell precursor acute lymphoblastic leukemia

OncoImmunology, 2018
CD19 immunotherapies based on T cells opened new avenues in the treatment of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, Fc engineered CD19 antibodies may also bear great potential.
Christian Kellner, Matthias Peipp, Martin Gramatzki, Martin Schrappe, Denis M. Schewe   +4 more
doaj   +1 more source

Clinical Implications of CD19-Negative Relapse Following CD19-Directed Therapy in B-Cell Acute Lymphoblastic Leukemia. [PDF]

Am J Hematol
CD19‐directed therapy remains the mainstay treatment for relapsed/refractory B‐cell acute lymphoblastic leukemia (ALL). However, treatment patterns and outcomes following CD19‐negative (CD19‐) relapse remain poorly defined. We retrospectively analyzed 65
Othman T, Agrawal V, Song JY, Gu Z, Koller P, Pourhassan H, Samara Y, Thiebaud JA, Tinajero J, Ngo D, Lin R, Sandhu K, AlMalki M, Aribi A, Otoukesh S, Ball B, Artz A, Salhotra A, Khaled S, Blackmon A, Amanam I, Ali H, Park S, Becker P, Nakamura R, Marcucci G, Stein A, Forman S, Pullarkat V, Aldoss I.   +29 more
europepmc   +2 more sources

Association Between Serum Ferritin and CD19/CD34 Expression in Pediatric Acute Lymphoblastic Leukemia [PDF]

Journal of Bioscience and Applied Research
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, characterized by malignant proliferation and accumulation of lymphoblasts in the bone marrow.
Karrar Tikki, Haider Jaffat
doaj   +1 more source

Onkogene Effekte von CD19: Vergleichende Untersuchungen an CD19-Verlustvarianten im murinen Burkitt Lymphom [PDF]

, 2020
Background: CD19 is constitutively expressed on B-Lymphocytes and is a central target antigen in modern immunotherapies for B-cell-neoplasia (1). These therapies with CD19 specific antibodies or effector cells can be limited by the loss of CD19 rendering
Delventhal, Kim
core   +1 more source

Association of CD24, CD27, and co-stimulatory molecules CD80 immunological marker expression on B-cells of human peripheral blood with development of celiac disease

Iraqi Journal of Hematology
BACKGROUND: B-cells express a variety of clusters of differentiation markers during development. These markers determine the basic function of the immune phenotype specific to B-cells.
Rahab Abd-Ali Al-Madany, Noor Abdulameer Oudah   +1 more
doaj   +1 more source

CAR-T Cell Therapy: A Door Is Open to Find Innumerable Possibilities of Treatments for Cancer Patients

Turkish Journal of Hematology, 2018
Seven years ago a chronic lymphocytic leukemia patient was for the first time successfully treated with chimeric antigen receptor (CAR)-modified T cells (CAR-T cells) to target CD19 overexpression in tumor cells. This was the beginning of the development
Lorena Perez - Amill, Berta Marzal, Alvaro Urbano - Ispizua, Manel Juan, Beatriz Martín - Antonio   +4 more
doaj   +1 more source

Table_1_Probiotic Lactobacillus rhamnosus GG Induces Alterations in Ileal Microbiota With Associated CD3-CD19-T-bet+IFNγ+/- Cell Subset Homeostasis in Pigs Challenged With Salmonella enterica Serovar 4,[5],12:i:-.DOC

, 2019
Salmonella enterica serovar 4,[5],12:i:- (S. 4,[5],12:i:-) is an emerging foodborne pathogen causing salmonellosis in humans and animals. Probiotic Lactobacillus rhamnosus GG (LGG) is an effective strategy for controlling enteric infections through ...
Guiyan Yang (4786875), Jiufeng Wang (1600588), Haifeng Ji (780358), Wei Zhang (405), Jiao Yu (4097278), Yaohong Zhu (6671660), Qiong Wu (84327)   +6 more
core   +1 more source

CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma

OncoImmunology, 2022
B cell lymphoma therapy has been transformed by CD19-targeting cellular therapeutics that induce high clinical response rates and impressive remissions in relapsed and refractory patients.
Lihe Su, Lan Wu, Roy R. Lobb, Paul D. Rennert, Christine Ambrose   +4 more
doaj   +1 more source

Assessment of selected B cells populations in the workers of X-ray departments

International Journal of Occupational Medicine and Environmental Health, 2014
Objectives: Workers of X-ray departments are occupationally exposed to long-term low levels of ionizing radiation (LLIR), which may affect their humoral immunity.
Piotr Kłuciński, Bogdan Mazur, Łukasz Sędek, Małgorzata Aptekorz, Paweł Cieślik, Antoni Hrycek, Gayane Martirosian   +6 more
doaj   +1 more source