Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]
The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A +9 more
core
Increase of DC-LAMP+ mature dendritic cell subsets in dermatopathic lymphadenitis of mycosis fungoides [PDF]
Background: Little is known about the immunological milieu of the skin-draining lymph nodes (LNs) in mycosis fungoides (MF). Objectives: We studied dendritic cell (DC) subsets in the dermatopathic lymphadenitis of MF patients.
Aoyama, Yumi +8 more
core +1 more source
11‐year‐old girl presenting with blurred vision and progressive right arm weakness
Brain Pathology, EarlyView.
Trung Toan Tran +6 more
wiley +1 more source
What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang +5 more
wiley +1 more source
HIV-1 tat addresses dendritic cells to induce a predominant th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection [PDF]
Tat is an early regulatory protein that plays a major role in human HIV-1 replication and AIDS pathogenesis, and therefore, it represents a key target for the host immune response.
Barillari, Giovanni +19 more
core +1 more source
scRNA‐seq of human adipose and diabetic wounds revealed a CCL2+ ADSC subpopulation with high stemness and ECM‐enriched pathways. These cells serve as a signaling hub via TGFB1‐TGFBR1, IL34‐CSF1R, and CCL2‐ACKR1. Their exosomes (CCL2‐Exos), carrying CCL2, TGFB1, and IL34, accelerate diabetic wound healing in mice by promoting angiogenesis, collagen ...
Songyun Zhao +10 more
wiley +1 more source
Background and Objective Tongue squamous cell carcinoma (TSCC) is the most prevalent oral cancer. Despite considerable advancements in treatment, the 5‐year survival rate remains relatively unchanged.
Narges Ghazi +3 more
doaj +1 more source
CD-1a immunoexpression in oral lichen planus and oral lichenoid reaction
Introduction: Oral lichen planus (OLP) is an immunologically mediated mucocutaneous diseases. Langerhans cells (LCs) are antigen presenting cells resident within oral mucosa which, together with intraepithelial lymphocytes, play a role in mucosal defense.
Azadeh Majidian +5 more
doaj
New Role of P. brasiliensis α-Glucan: Differentiation of Non-conventional Dendritic Cells
The cell wall has a critical role in the host immune response to fungal pathogens. In this study, we investigated the influence of two cell wall fractions of the dimorphic fungi Paracoccidioides brasiliensis (Pb) in the in vitro generation of monocyte ...
Ana Camila Oliveira Souza +9 more
doaj +1 more source
Immunophenotype in orofacial granulomatosis with and without Crohn's disease [PDF]
Objectives: The aim of this investigation was to characterise and compare the inflammatory infiltrates in patients with orofacial granulomatosis solely (OFG-S) and OFG with coexisting Crohn's disease (OFG+CD).
Gale, Gita +5 more
core +1 more source

