Thymus transplantation for complete DiGeorge syndrome: European experience [PDF]
Background: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods: Twelve patients with cDGS were transplanted with allogeneic cultured thymus.
Adrian J. Thrasher +59 more
core +3 more sources
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang +8 more
wiley +1 more source
Reduced Number of CD1a+ Cells in Cutaneous B-Cell Lymphoma [PDF]
Cutaneous B-cell lymphoma is difficult to distinguish from pseudolymphoma. The histologic pattern and monoclonal restriction (immunohistochemical analysis and molecular biology) are the criteria used for differentiating these entities. CD1a+ dendritic cells have been observed in the infiltrates of T-cell lymphoma, but the presence of these CD1a+ cells ...
M, Schmuth +4 more
openaire +2 more sources
Characterization of the inflammatory cell infiltrate and expression of costimulatory molecules in chronic echinococcus granulosus infection of the human liver [PDF]
Background: The local immune responses to chronic echinococcal infections in various organs are largely unknown. Since the liver is the most frequently involved organ in such infections in human we aimed to characterize the inflammatory as well as immune
A Nolan +65 more
core +1 more source
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
Anti-CD1a CAR T cells to selectively target T-ALL [PDF]
In this issue of Blood, Sanchez-Martinez and colleagues present a novel approach to the treatment of T-acute lymphoblastic leukemia (T-ALL) using chimeric antigen receptor (CAR) T cells redirected against CD1a1 in in vitro and xenograft models.
Paul M. Maciocia, Martin A. Pule
openaire +2 more sources
Polymorphism in Exon 2 of CD1 Genes in Southwest of Iran.
The CD1 family is less variable transmembrane antigen presenting molecules related to the MHC molecules. CD1a and CD1e genes are the most polymorphic ones associated with autoimmune diseases.
Hossein Golmoghaddam +3 more
doaj +2 more sources
Expression of cluster of differentiation 1a-positive langerhans cells in oral lichen planus
Background/Purpose: Lichen planus is a T-cell-mediated mucocutaneous disorder characterized histopathologically by a band of chronic inflammatory cells in the subepithelial zone and degeneration of basal layer. The present study was aimed to evaluate the
Thankanadar Arul Kumar +5 more
doaj +1 more source
Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M. +7 more
core
Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer.
BACKGROUND: While lymph node metastasis is among the strongest predictors of disease-free and overall survival for patients with breast cancer, the immunological nature of tumor-draining lymph nodes is often ignored, and may provide additional prognostic
Holbrook E Kohrt +5 more
doaj +2 more sources

