Results 61 to 70 of about 21,316 (223)

Thymus transplantation for complete DiGeorge syndrome: European experience [PDF]

open access: yes, 2017
Background: Thymus transplantation is a promising strategy for the treatment of athymic complete DiGeorge syndrome (cDGS). Methods: Twelve patients with cDGS were transplanted with allogeneic cultured thymus.
Adrian J. Thrasher   +59 more
core   +3 more sources

A Rare Case of Cutaneous Crystal‐Storing Histiocytosis With Kappa Light Chain Restriction and Unusual BCL6 Expression

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Crystal‐storing histiocytosis (CSH) is a rare histopathologic phenomenon characterized by the accumulation of crystalline material within histiocytes, most often associated with lymphoplasmacytic or plasma cell neoplasms. Cutaneous involvement is uncommon and may present diagnostic challenges.
Liangli Wang   +8 more
wiley   +1 more source

Reduced Number of CD1a+ Cells in Cutaneous B-Cell Lymphoma [PDF]

open access: yesAmerican Journal of Clinical Pathology, 2001
Cutaneous B-cell lymphoma is difficult to distinguish from pseudolymphoma. The histologic pattern and monoclonal restriction (immunohistochemical analysis and molecular biology) are the criteria used for differentiating these entities. CD1a+ dendritic cells have been observed in the infiltrates of T-cell lymphoma, but the presence of these CD1a+ cells ...
M, Schmuth   +4 more
openaire   +2 more sources

Characterization of the inflammatory cell infiltrate and expression of costimulatory molecules in chronic echinococcus granulosus infection of the human liver [PDF]

open access: yes, 2015
Background: The local immune responses to chronic echinococcal infections in various organs are largely unknown. Since the liver is the most frequently involved organ in such infections in human we aimed to characterize the inflammatory as well as immune
A Nolan   +65 more
core   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

open access: yesThe FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs   +7 more
wiley   +1 more source

Anti-CD1a CAR T cells to selectively target T-ALL [PDF]

open access: yesBlood, 2019
In this issue of Blood, Sanchez-Martinez and colleagues present a novel approach to the treatment of T-acute lymphoblastic leukemia (T-ALL) using chimeric antigen receptor (CAR) T cells redirected against CD1a1 in in vitro and xenograft models.
Paul M. Maciocia, Martin A. Pule
openaire   +2 more sources

Polymorphism in Exon 2 of CD1 Genes in Southwest of Iran.

open access: yesIranian Journal of Public Health, 2013
The CD1 family is less variable transmembrane antigen presenting molecules related to the MHC molecules. CD1a and CD1e genes are the most polymorphic ones associated with autoimmune diseases.
Hossein Golmoghaddam   +3 more
doaj   +2 more sources

Expression of cluster of differentiation 1a-positive langerhans cells in oral lichen planus

open access: yesIndian Journal of Dermatology, 2019
Background/Purpose: Lichen planus is a T-cell-mediated mucocutaneous disorder characterized histopathologically by a band of chronic inflammatory cells in the subepithelial zone and degeneration of basal layer. The present study was aimed to evaluate the
Thankanadar Arul Kumar   +5 more
doaj   +1 more source

Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]

open access: yes, 2013
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M.   +7 more
core  

Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer.

open access: yesPLoS Medicine, 2005
BACKGROUND: While lymph node metastasis is among the strongest predictors of disease-free and overall survival for patients with breast cancer, the immunological nature of tumor-draining lymph nodes is often ignored, and may provide additional prognostic
Holbrook E Kohrt   +5 more
doaj   +2 more sources

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