PURPOSE: To morphometrically quantify CD1a+ dentritic cells and DC-SIGN+ dendritic cells in HIV-positive patients with anal squamous intraepithelial neoplasia and to evaluate the effects of HIV infection, antiretroviral therapy and HPV infection on ...
Adriana Gonçalves Daumas Pinheiro Guimarães +11 more
doaj +1 more source
Background: Guillain–Barré Syndrome (GBS) is an acute acquired autoimmune inflammatory disorder of peripheral nerves and roots. The pathogenesis is essentially an aberrant post-infectious immune response in a genetically susceptible host milieu.
Rajarshi Chakraborty +11 more
doaj +1 more source
CTLA4 is expressed on mature dendritic cells derived from human monocytes and influences their maturation and antigen presentation [PDF]
Background Dendritic cells (DCs) initiate immune responses through their direct interaction with effector cells. However, the mechanism by which DC activity is regulated is not well defined. Previous studies have shown that CTLA4 on T cells regulates DCs
Ni Zhen H +6 more
core +2 more sources
Two canine CD1a proteins are differentially expressed in skin [PDF]
Lipid antigens are presented to T cells by the CD1 family of proteins. In this study, we characterize the complete dog (Canis familiaris) CD1 locus, which is located on chromosome 38. The canine locus contains eight CD1A genes (canCD1A), of which five are pseudogenes, one canCD1B, one canCD1C, one canCD1D, and one canCD1E gene.
Looringh Van Beeck, Frank A. +7 more
openaire +5 more sources
A dendritikus sejtek szerepe az immunológiai szinapszis kialakításában, a T-limfociták homeosztázisának és aktiválásának szabályozásában = The role of dendritic cells in the formation of immunological synapses and in the regulation of T lymphocyte homeostasis and activation [PDF]
A CD14+ monociták CD1a- és CD1a+ DS-ekké differenciálódnak, de a CD1a- és CD1a+ sejtek arányát a szérum lipoproteinek dózis függően befolyásolják. Kinetikai vizsgálatok igazolták, hogy az éretlen CD1a- DS-ek CD1a+ sejtekké differenciálódnak, ezt az ...
Gogolák, Péter +2 more
core
An improved ontological representation of dendritic cells as a paradigm for all cell types [PDF]
The Cell Ontology (CL) is designed to provide a standardized representation of cell types for data annotation. Currently, the CL employs multiple is_a relations, defining cell types in terms of histological, functional, and lineage properties, and the ...
Arighi Cecilia, N. +7 more
core
CD1a expression in psoriatic skin following treatment with propylthiouracil, an antithyroid thioureylene [PDF]
BackgroundThe antithyroid thioureylenes, propylthiouracil (PTU) and methimazole (MMI), are effective in the treatment of patients with plaque psoriasis. The mechanism of action of the drugs in psoriasis is unknown.
Alan N Elias +42 more
core +1 more source
ABSTRACT Cutaneous crystal‐storing histiocytosis (CSH) is an extremely rare histopathologic finding of histiocytes accumulating crystals of immunoglobulin or paraproteins, often associated with lymphoplasmacytic malignancies. It commonly presents in a wide age range of both female and male adults with a history of a lymphoproliferative disorder ...
Ashton Arlen +3 more
wiley +1 more source
CD1a and langerin: acting as more than Langerhans cell markers [PDF]
Langerhans cells (LCs) represent a unique DC subset populating the outermost body surface, i.e., the epidermis. Although CD1a and langerin (CD207) are used as specific markers to distinguish LCs from other DC subsets, their immunological functions have remained mostly unknown.
Norikatsu, Mizumoto, Akira, Takashima
openaire +2 more sources
An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey +3 more
core

