Results 51 to 60 of about 15,620 (207)

Microsatellite unstable colorectal cancers are associated with increased CD1a- and CD83-positive dendritic cell infiltration

open access: yesBiotechnology & Biotechnological Equipment, 2023
Microsatellite instability (MSI) is characterized by a highly immunogenic tumor phenotype and abundant lymphocytic infiltrates. The aim of this study was to investigate the association between four immunohistochemically determined classes of dendritic ...
Maya Gulubova   +5 more
doaj   +1 more source

Dendritic Cell Subsets in Oral Mucosa of Allergic and Healthy Subjects. [PDF]

open access: yesPLoS ONE, 2016
Immunohistochemistry was used to identify, enumerate, and describe the tissue distribution of Langerhans type (CD1a and CD207), myeloid (CD1c and CD141), and plasmacytoid (CD303 and CD304) dendritic cell subsets in oral mucosa of allergic and non ...
Susanne M Reinartz   +5 more
doaj   +1 more source

Impact of autologous plasma on expression of CD1a and CD1a-associated functional dichotomy.

open access: yes, 2015
a) CD1a expression histogram plots of moDC generated from two individuals with opposite response patterns to autologous plasma (AP). The left plot depicts moDC that upregulated CD1a in the presence of AP while the individual represented in the right plot
Evelyn Bauer (812517)   +4 more
core   +1 more source

Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors [PDF]

open access: yes, 2022
CD1a is a monomorphic antigen-presenting molecule on dendritic cells that presents lipids to αβ T cells. Whether CD1a represents a ligand for other immune receptors remains unknown.
Ocampo, Tonatiuh A.   +11 more
core   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak   +2 more
wiley   +1 more source

HLA-DR surface expression in CD1a+ and CD1a−negative DC derived from septic patients.

open access: yes, 2013
Flow cytometry analysis of HLA-DR in monocytes, and in CD1a+ and CD1a−negative DC purified at day 3 of monocyte differentiation (immature DC, iDC) and cultured an additional 48 h in the presence of LPS at 10 ng/ml (mature DC, mDC). Patients, filled boxes;
Arnaud Alves (303754)   +5 more
core   +1 more source

CD1a: a novel biomarker for Barrett's metaplasia? [PDF]

open access: yesThe Lancet Oncology, 2003
educational book. Alexandria: American Society for Clinical Oncology, 2001: 226–44. 49 Hussain M, Smith DC, Al-Sukhun S, et al. Preliminary results of HER-2/neu screening and treatment with trastuzumab (Herceptin) (T), paclitaxel (P), carboplatin (C) and gemcitabine (G) in patients with advanced urothelial cancer. Proc Am Soc Clin Oncol 2002; 21: 800a.
CAPPELLO, Francesco   +3 more
openaire   +3 more sources

Langerhans cells in lichen planus and lichenoid mucositis an immunohistochemical study

open access: yesJournal of Pharmacy and Bioallied Sciences, 2014
Aim: The aim of this study is to identify and evaluate Langerhans cell (LC) in lichen planus (LP), lichenoid mucositis (LM) and normal mucosa (NM) using CD1a monoclonal antibody immunohistochemically.
M Devi   +5 more
doaj   +1 more source

Lupus Panniculitis Immunoprofiling Reveals a Cytotoxic, Type 1‐Skewed T‐Cell Response With Signs of Metabolic Alteration

open access: yesAllergy, EarlyView.
Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri   +11 more
wiley   +1 more source

Solitary Indeterminate Cell Histiocytosis Presenting as a Reddish Nodule on the Abdomen of a 4‐Year‐Old Boy: Clinicopathologic Correlation and Electron Microscopy Findings

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Indeterminate cell histiocytosis (ICH) is a clonal proliferative disorder of mononuclear phagocyte cells that shows features of both dendritic and histiocytic cells. Only around 100 cases of ICH were reported, and among them, only 24% of reported cases involve pediatric patients, with a mean age at diagnosis of 50 years.
Seung‐Soo Lee   +3 more
wiley   +1 more source

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