Results 241 to 250 of about 142,249 (285)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Opto-CD28-REACT: optogenetic co-stimulatory receptor activation on non-engineered human T cells. [PDF]

Front Immunol
Ehret AK, Hartmann S, Salavei P, Andreani V, Gensch N, Gámez-Díaz L, Schamel WW.   +6 more
europepmc   +1 more source

The Role of Belatacept‐Use and Senescence on Infectious and Mortality Complications After Kidney Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam, Abdinoor Abdi, Wyatt Tarter, Ben Langworthy, Adam Bregman, Karam M. Obeid   +5 more
wiley   +1 more source

Causal relationship between palmitoylation genes mediated by immune cell phenotypes and oral cancer: A Mendelian randomized study. [PDF]

Medicine (Baltimore)
Jiang ZH, Wei YH, Xie H, Wang HB, He W, Wang XJ.   +5 more
europepmc   +1 more source

C‐X‐C chemokine receptor CXCR4 mediates diurnal changes in the aggregation and dispersion of CD8+ T cells within the tumor microenvironment

International Journal of Cancer, Volume 158, Issue 6, Page 1740-1754, 15 March 2026.
What's new? In addition to governing daily variations in biological activity, the circadian clock regulates immune cell migration into tumors. Whether this influence extends to immune cell localization within the tumor microenvironment (TME) is unknown. Here, using cell and animal models, the authors investigated immune cell distribution within the TME
Akito Tsuruta, Marina Fujimoto, Yasuha Hiraoka, Aoi Taniguchi, Yuki Shiiba, Takuto Inoki, Tomoaki Yamauchi, Yuya Yoshida, Naoya Matsunaga, Shigehiro Ohdo, Satoru Koyanagi   +10 more
wiley   +1 more source

CAR Intrinsic Design Pre-Shapes Transcriptional and Metabolic Networks in CAR T Cells. [PDF]

Metabolites
Agac Cobanoglu D, Franklin S, Hu Y, Boland DJ, Song X.   +4 more
europepmc   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 2, Page 127-143, March 2026.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

Next-generation CAR-T cells design: leveraging tumor features for enhanced efficacy. [PDF]

Mol Cancer
Lei Y, Liu N, Qin D, Liu M, Wang Y.
europepmc   +1 more source

Lymphoid gene expression supports neuroprotective microglia function. [PDF]

Nature
Ayata P, Crowley JM, Challman MF, Sahasrabuddhe V, Gratuze M, Werneburg S, Ribeiro D, Hays EC, Durán-Laforet V, Faust TE, Hwang P, Mendes Lopes F, Nikopoulou C, Buchholz S, Murphy RE, Mei T, Pimenova AA, Romero-Molina C, Garretti F, Patel TA, De Sanctis C, Ramirez Jimenez AV, Crow M, Weiss FD, Ulrich JD, Marcora E, Murray JW, Meissner F, Beyer A, Hasson D, Crary JF, Schafer DP, Holtzman DM, Goate AM, Tarakhovsky A, Schaefer A.   +35 more
europepmc   +1 more source