Results 81 to 90 of about 280,132 (264)
Immune cells and tryptophan metabolism in the joint capsule tissue in rheumatoid arthritis
Acta Biomedica ScientificaTo the present day, many links in the pathogenesis of rheumatoid arthritis remain unclear, which leads to unsatisfactory results in its therapy.The aim.
E. A. Stepanov
doaj +1 more source
Frequency of RORγt and T-bet expression in CD3+, CD3+CD4+, CD3+CD8+ lymphocytes.
, 2019 A-G. Expression of transcription factors RORγt and T-bet in CD3+, CD3+CD4+, and CD3+CD8+ Lymphocytes and in CD3+ Naive (N), Central Memory (CM), Effector Memory (EM), and Terminally Differentiated (TD) Cells. Co-expression of T-bet in CD3+, CD3+CD4+, and
Thomas Ryan (6196559) +8 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source
Indicii imunității la pacienții cu tuberculoză pulmonară sub influența tratamentului complex
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019 La 49 de pacienți cu tuberculoză pulmonară asociată cu toxocaroză, care au urmat tratament standard antituberculos, antiparazitar și imunocorectiv, a fost studiată dinamica indicilor răspunsului imun Th1 și Th2 și prezența corelației IL-5 cu eozinofilia ...
Angela Guila +5 more
doaj
Characteristics of BsAb (EphA10/CD3) and BsAb (His/CD3).
, 2015 (A) Gene construct of operons encoding each BsAb in plasmid pcDNA3.1. (B) Gel filtration chromatography profile of BsAb (EphA10/CD3) and BsAb (His/CD3), which were purified with IMAC.
Kazuma Higashisaka (838225) +8 more
core +1 more source
PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe
Advanced Science, EarlyView.This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao +14 more
wiley +1 more source
Pathomorphological brain changes due to coronavirus disease 2019 (COVID-19)
PatologìâAim: To investigate the pathomorphological changes in the brains of individuals who died from complications of coronavirus disease (COVID-19) and to identify the neuropathological features associated with COVID-19. Materials and methods.
L. I. Volos, H. L. Stoliar
doaj +1 more source
Журнал инфектологии, 2014 In the present study factors of immune system in peripheral blood (PB) of patients with chronic hepatitis C (CHС) with the different degree of fibrosis were determined.
V. Yu. Nikitin +3 more
doaj +1 more source
Apoptosis under CD3/CD28 stimulation.
, 2013 A. Representative plots demonstrating upregulation of CD25 in response to CD3/CD28 stimulation in mixed splenocyte cultures. B. Spontaneous apoptosis in isolated (n = 4) and gated cells (n = 5) in reference to responsiveness (CD25 expression) to CD3 ...
Enosh M. Askenasy (349060) +4 more
core +1 more source
Advanced Science, EarlyView.The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang +10 more
wiley +1 more source