Results 81 to 90 of about 304,036 (298)

Diagnostic significance of the determination of peripheral blood lymphocytes for predicting the onset of pregnancy in patients with repeated implant failures in groups with different protocols of the assisted reproductive technology program [PDF]

open access: yesГинекология, 2017
Purpose of the study. Study of the diagnostic significance of the determination of peripheral blood lymphocytes with phenotypes significantly different from the control values for predicting the onset of pregnancy in groups with different protocols of ...
T S Amyan   +4 more
doaj  

CD3 ALDOSTERONISM, HEART AND VESSELS

open access: yesArtery Research, 2015
It has been documented that absolute aldosterone excess in patients with primary aldosteronism (PA) has been associated with higher risk of heart, vascular and kidney damage independent on blood pressure and resulting in increased total cardiovascular ...
Aleksander Prejbisz
doaj   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

open access: yesAdvanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin   +20 more
wiley   +1 more source

Immune cells and tryptophan metabolism in the joint capsule tissue in rheumatoid arthritis

open access: yesActa Biomedica Scientifica
To the present day, many links in the pathogenesis of rheumatoid arthritis remain unclear, which leads to unsatisfactory results in its therapy.The aim.
E. A. Stepanov
doaj   +1 more source

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

Indicii imunității la pacienții cu tuberculoză pulmonară sub influența tratamentului complex

open access: yesBuletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2019
La 49 de pacienți cu tuberculoză pulmonară asociată cu toxocaroză, care au urmat tratament standard antituberculos, antiparazitar și imunocorectiv, a fost studiată dinamica indicilor răspunsului imun Th1 și Th2 și prezența corelației IL-5 cu eozinofilia ...
Angela Guila   +5 more
doaj  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

CD3-negative lymphokine-activated cytotoxic cells express the CD3 epsilon gene.

open access: yes, 1988
The expression of genes encoding different polypeptide chains of the TCR-CD3 complex was analyzed in a panel of cloned MHC-unrestricted cytotoxic cells. The clones were derived from CD3+ and CD3- human PBL.
Prigione I   +4 more
core   +1 more source

Pathomorphological brain changes due to coronavirus disease 2019 (COVID-19)

open access: yesPatologìâ
Aim: To investigate the pathomorphological changes in the brains of individuals who died from complications of coronavirus disease (COVID-19) and to identify the neuropathological features associated with COVID-19. Materials and methods.
L. I. Volos, H. L. Stoliar
doaj   +1 more source

The immunologic characteristic of the stages of chronic hepatitis C and an assessment of immune system factors as prognostic criteria of a current disease

open access: yesЖурнал инфектологии, 2014
In the present study factors of immune system in peripheral blood (PB) of patients with chronic hepatitis C (CHС) with the different degree of fibrosis were determined.
V. Yu. Nikitin   +3 more
doaj   +1 more source

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