Results 121 to 130 of about 207,399 (316)
We compared the cell division behavior of CD34(-) and CD34(+) (CD33/CD38/CD71)-negative (Lin(-)) CD133(+) cord blood cells stimulated with the cytokines Flt3-ligand, stem cell factor, and thrombopoietin. Within a 4-day time frame, Lin(-)CD34(-) CD133(+) (
Götze, KS;Schiemann, M;Marz, S;Jacobs, VR;Debus, G;Peschel, C;Oostendorp, RA
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Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
E-cadherin/CD34 double immunostaining in placental diagnosis
Placental foetal vascular malperfusion (FVM) may be responsible for complicated foetal or neonatal condition. By highlighting endothelial fragmentation, the double E-cadherin/CD34 immunostain highlights distal villous endothelial fragmentation of recent ...
Jerzy Stanek
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Liver fibrosis represents the end stage of chronic liver inflammatory diseases and is defined by the abnormal accumulation of extracellular matrix in the liver. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension.
Lee, Po-Huang;Tu, Chi-Tang;Hsiao, Chih-Chiang;Tsai, Ming-Song;Ho, Cheng-Maw;Cheng, Nai-Chen;Hung, Tzu-Min;Shih, Daniel Tzu-Bi +1 more
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Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue
ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados +5 more
wiley +1 more source
Optimal proportion CD34+ cells to CD34− cells for effective EPC differentiation.
The optimal proportion of CD34+ cells to CD34− cells was estimated by coculture of CD34+ cells (500 cells per 35-mm dish) with various densities of CD34− cells (100, 50, 20, 10, 5, 2.5, 1.7, 1.25, 1, 0.3, and 0% of CD34+ cells).
Da-Yeon Kim (622779) +14 more
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Abstract Measurable residual disease (MRD) monitoring by multiparameter flow cytometry (MFC) is well established in bone marrow (BM) samples for acute myeloid leukemia (AML), but its use in peripheral blood (PB) remains less developed. We adapted a semi‐automated and well validated MFC‐MRD assay, originally developed for BM, to PB aiming to evaluate ...
Jonas Schadt +8 more
wiley +1 more source
Translocation of the mixed-lineage leukemia (MLL) gene with AF4, AF9, or ENL results in acute leukemia with both lymphoid and myeloid involvement.
Mizutani, Shuki +39 more
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Abstract Systemic mastocytosis (SM) is a clonal mast cell (MC) disorder characterized by aberrant immunophenotypes, including expression of CD25, CD2, and occasionally CD30. CD123, the α‐subunit of the interleukin‐3 receptor, is a therapeutic target in hematologic malignancies and has been reported to be expressed on neoplastic MCs by ...
Ryan C. Shean +2 more
wiley +1 more source
Transient loading of CD34+ hematopoietic progenitor cells with polystyrene nanoparticles
Sarah Deville,1,2 Wahyu Wijaya Hadiwikarta,1 Nick Smisdom,1,2 Bart Wathiong,1,3 Marcel Ameloot,2 Inge Nelissen,1 Jef Hooyberghs1,3 1VITO, Flemish Institute for Technological Research, Mol, Belgium; 2Biomedical Research Institute, Hasselt University ...
Deville S +6 more
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