Results 141 to 150 of about 287,679 (291)

Nilotinib interferes with cell cycle, ABC transporters and JAK-STAT signaling pathway in CD34+/lin- cells of patients with chronic phase chronic myeloid leukemia after 12 months of treatment

, 2019
Alessandra Trojani, Ester Pungolino, Alessandra Dal Molin, Milena Lodola, Giuseppe Rossi, Mariella D’Adda, Alessandra Perego, Chiara Elena, Mauro Turrini, Lorenza Borin, Cristina Bucelli, Simona Malato, Maria Cristina Carraro, Francesco Spina, Maria Luisa Latargia, Salvatore Artale, Pierangelo Spedini, Michela Anghilieri, Barbara Di Camillo, Giacomo Baruzzo, Gabriella De Canal, Alessandra Iurlo, Enrica Morra, Roberto Cairoli   +23 more
openalex   +2 more sources

Engineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment

Advanced Science, EarlyView.
This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao   +17 more
wiley   +1 more source

DFO Enhances the Targeting of CD34-Positive Cells and Improves Neovascularization [PDF]

, 2015
Zijing Du, Tao Zan, Xiaolu Huang, Lingling Sheng, Haizhou Li, Hua Li, Qingfeng Li   +6 more
openalex   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

A Clinicopathological Study of 24 Cases of DFSP

Journal of Plastic and Reconstructive Surgery
Objectives: Dermatofibrosarcoma protuberans (DFSP) usually arises in the dermis and spreads to the underlying subcutaneous tissue (cutaneous DFSP). However, it rarely appears in the subcutaneous tissue (subcutaneous DFSP).
Miyako Kachi, Atsumori Hamahata, Kohei Oashi, Hisato Konoeda, Miho Kirita, Masashi Ishikawa, Hirotaka Koyanagi, Hiroyuki Sakurai   +7 more
doaj  

CD99 expressed on human mobilized peripheral blood CD34+ cells is involved in transendothelial migration [PDF]

, 2006
Anne‐Marie Imbert, Ghania Belaaloui, Florence Bardin, Cécile Tonnelle, Marc Lopez, Christian Chabannon   +5 more
openalex   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Superficial CD34 Positive Fibroblastic Tumor: A rare mesenchymal tumor of borderline malignant potential.

Journal of Pathology of Nepal
Superficial CD34 positive fibroblastic tumor is a rare soft tissue tumor first brought to light by Jodi M Carter in 2014. Several cases have been reported since, and they have been newly included in the recent WHO classification under the fibroblastic ...
Pradnya Kamble, Jayashree Chaudhari, Manisha Khare   +2 more
doaj   +1 more source

Low Phosphatidylserine+ Cells Within the CD34+/CD45dim/CD117(c-kit)+ Subpopulation Are Associated with Poor Outcomes in Metastatic Colorectal Cancer [PDF]

Davide Brocco, Pasquale Simeone, Pietro Di Marino, Domenico De Bellis, Francesca D’Ascanio, Gaia Colasante, Antonino Grassadonia, Michele De Tursi, Rosalba Florio, Mauro Di Ianni, Alessandro Cama, Nicola Tinari, Paola Lanuti   +12 more
openalex   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source