Results 131 to 140 of about 71,651 (313)
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
Cell Proliferation, EarlyView.One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye +6 more
wiley +1 more source
Systemic lupus erythematosus, thrombocytopenia, microangiopathic haemolytic anaemia and anti-CD36 antibodies. [PDF]
, 1997 Rustam Al‐Shahi Salman +6 more
openalex +1 more source
Cell Proliferation, EarlyView.Schematic diagram illustrating the molecular mechanisms of the Cx3cl1‐Cx3cr1 axis mediated by rTMS activation of GABAergic neurons in the process of cognitive function recovery in AD. ABSTRACT This study aimed to investigate the impact of repetitive transcranial magnetic stimulation (rTMS) on cognitive recovery in Alzheimer's disease (AD) by exploring ...
Yunxiao Kang +7 more
wiley +1 more source
β-Amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase [PDF]
, 2004 β-Amyloid (βA) peptide is strongly implicated in the neurodegeneration underlying Alzheimer's disease, but the mechanisms of neurotoxicity remain controversial. This study establishes a central role for oxidative stress by the activation of NADPH oxidase
Abramov, A.Y. +2 more
core
Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL [PDF]
, 1998 Dominica Calvo +4 more
openalex +1 more source
Cell Proliferation, EarlyView.EC‐EXOs could regulate the differentiation of BMSCs through the key protein THBS3, which inhibits their differentiation to lipogenic cells and promotes their differentiation to osteoblasts. THBS3 could down‐regulate the expression of its downstream target CD47 and delay the process of bone loss in aged mice and OVX mice, which may provide a novel ...
Jiaojiao Wang +8 more
wiley +1 more source
Journal of Lipid Research, 2019 Fatty acid translocase cluster of differentiation (CD36) is a multifunctional membrane protein that facilitates the uptake of long-chain fatty acids. Lipophagy is autophagic degradation of lipid droplets.
Yun Li +10 more
doaj
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Cell Proliferation, EarlyView.Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen +9 more
wiley +1 more source
Melanoma-Derived Extracellular Vesicles Induce CD36-Mediated Pre-Metastatic Niche
BiomoleculesCD36 expression in both immune and non-immune cells is known to be directly involved in cancer metastasis. Extracellular vesicles (EVs) secreted by malignant melanocytes play a vital role in developing tumor-promoting microenvironments, but it is unclear
Shankar Suman +13 more
doaj +1 more source
Molecular Basis of CD36 Deficiency
Japanese Journal of Thrombosis and Hemostasis, 1996 We have analyzed molecular basis of CD36 deficiency and identified three mutations responsible for CD36 deficiency: 1) a 478C→T substitution in codon 90 (proline90→serine), 2) a dinucleotide deletion in colon 110, and 3) a single nucleotide insertion in codon 317. The 478C→T (proline90→serine) substitution seemed to be the most common mutation. We have
openaire +3 more sources