Results 11 to 20 of about 83,609 (361)
The role of CD36 in cardiovascular disease [PDF]
Cardiovascular Research, 2020 Abstract CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty acids, the main metabolic substrate in myocardial tissue.
Hongyang Shu +5 more
openaire +4 more sources
Role of CD36 in cancer progression, stemness, and targeting
Frontiers in Cell and Developmental Biology, 2022 CD36 is highly expressed in diverse tumor types and its expression correlates with advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases fatty acid uptake, reprogramming lipid metabolism; 2) favors cancer cell ...
Sandra L. Guerrero-Rodríguez +6 more
doaj +2 more sources
npj Breast Cancer, 2021 Adipocytes influence breast cancer behaviour via fatty acid release into the tumour microenvironment. Co-culturing human adipocytes and breast cancer cells increased CD36 expression, with fatty acid import into breast cancer cells.
Jones Gyamfi +8 more
doaj +2 more sources
Erythroid involvement in CD36 deficiency [PDF]
Experimental Hematology, 2001 The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. The two types of platelet CD36 deficiency, types I and II, are associated with the absence and presence of CD36 on monocytes, respectively. To clarify the involvement of the erythroid lineage in CD36 deficiency, we investigated the phenotype and RNA ...
Ken Toba +9 more
openalex +4 more sources
Cell Death and Disease, 2021 Metabolic reprogramming is a new hallmark of cancer but it remains poorly defined in hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both lipid and glucose metabolism in the liver.
Xiaoqing Luo +11 more
doaj +2 more sources
CD36 deficiency and insulin resistance [PDF]
The Lancet, 2001 Hitoshi Chiba +4 more
+13 more sources
Cell Discovery, 2023 Hepatocellular carcinoma (HCC) is an immunotherapy-resistant malignancy characterized by high cellular heterogeneity. The diversity of cell types and the interplay between tumor and non-tumor cells remain to be clarified.
Guiqi Zhu +19 more
semanticscholar +1 more source
CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate
Journal of Experimental Medicine, 2022 CD36 functions as both a signaling receptor and fatty acid transporter in various immune and non-immune cells. This review summarizes how its dual functions determine immune cell functions and fates, which contribute to common diseases including ...
Yiliang Chen +3 more
semanticscholar +1 more source
CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease.
Physiological Reviews, 2023 The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and plays a key regulatory role in cellular lipid metabolism. CD36 facilitates the cellular uptake of long-chain fatty acids, mediates lipid signaling, and regulates ...
J. F. Glatz, L. Heather, J. Luiken
semanticscholar +1 more source
The Role of CD36 in Cancer Progression and Its Value as a Therapeutic Target
Cells, 2023 Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical roles in many different types of cancer, notably breast, brain, and ovarian cancers.
W. Feng, Hannah T. Zuppe, M. Kurokawa
semanticscholar +1 more source