Results 11 to 20 of about 81,560 (343)
The role of CD36 in cardiovascular disease [PDF]
Cardiovascular Research, 2020 CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty acids, the main metabolic substrate in myocardial tissue.
Hongyang Shu +5 more
semanticscholar +4 more sources
npj Breast Cancer, 2021 Adipocytes influence breast cancer behaviour via fatty acid release into the tumour microenvironment. Co-culturing human adipocytes and breast cancer cells increased CD36 expression, with fatty acid import into breast cancer cells.
Jones Gyamfi +8 more
doaj +2 more sources
Role of CD36 in cancer progression, stemness, and targeting
Frontiers in Cell and Developmental Biology, 2022 CD36 is highly expressed in diverse tumor types and its expression correlates with advanced stages, poor prognosis, and reduced survival. In cancer cells, CD36: 1) increases fatty acid uptake, reprogramming lipid metabolism; 2) favors cancer cell ...
Sandra L. Guerrero-Rodríguez +6 more
doaj +2 more sources
Cell Death and Disease, 2021 Metabolic reprogramming is a new hallmark of cancer but it remains poorly defined in hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both lipid and glucose metabolism in the liver.
Xiaoqing Luo +11 more
doaj +2 more sources
CD36 Signaling in Diabetic Cardiomyopathy
Aging and disease, 2021 Cluster of differentiation 36 (CD36), also referred to as scavenger receptor B2, has been shown to serve multiple functions in lipid metabolism, inflammatory signaling, oxidative stress, and energy reprogramming.
Xudong Zhang +4 more
semanticscholar +4 more sources
Erythroid involvement in CD36 deficiency [PDF]
Experimental Hematology, 2001 The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. The two types of platelet CD36 deficiency, types I and II, are associated with the absence and presence of CD36 on monocytes, respectively. To clarify the involvement of the erythroid lineage in CD36 deficiency, we investigated the phenotype and RNA ...
Ken Toba +9 more
openalex +4 more sources
Translational Psychiatry, 2021 Both inflammatory processes and gut microbiota have been implicated in the pathophysiology of depressive disorders. The class B scavenger receptor CD36 is involved in the cytotoxicity associated with inflammation.
Shunjie Bai +9 more
doaj +2 more sources
CD36 deficiency and insulin resistance [PDF]
The Lancet, 2001 Hitoshi Chiba +4 more
+13 more sources
Journal of Lipid Research, 2019 Fatty acid translocase cluster of differentiation (CD36) is a multifunctional membrane protein that facilitates the uptake of long-chain fatty acids. Lipophagy is autophagic degradation of lipid droplets.
Yun Li +10 more
doaj +2 more sources
Cell Discovery, 2023 Hepatocellular carcinoma (HCC) is an immunotherapy-resistant malignancy characterized by high cellular heterogeneity. The diversity of cell types and the interplay between tumor and non-tumor cells remain to be clarified.
Guiqi Zhu +19 more
semanticscholar +1 more source