ABSTRACT Background Anticancer chemotherapy is an underappreciated contributor to cancer cachexia, an often‐irreversible body‐wasting condition that causes 20%–30% of cancer‐related deaths. An obstacle to predicting, monitoring and understanding the mechanisms underlying chemotherapy cachexia is that each cancer (and subtype) is assigned different ...
Dean G. Campelj+9 more
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Neurotensin promotes hepatic steatosis by regulating lipid uptake and mitochondrial adaptation in hepatocytes. [PDF]
Banerjee M+16 more
europepmc +1 more source
Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1 [PDF]
Paul Shore
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Minimal Residual Disease Detection: Implications for Clinical Diagnosis and Cancer Patient Treatment
Currently, a variety of methods such as flow cytometry, polymerase chain reaction, next‐generation sequencing, and other emerging methods are used for the detection of minimal residual disease, each of which has its own unique strengths and limitations and, more importantly, promising clinical applications.
Meiling Song+10 more
wiley +1 more source
α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT-FOXO1-CD36 pathway. [PDF]
Bai X+8 more
europepmc +1 more source
Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li+3 more
wiley +1 more source
Liver TET1 promotes metabolic dysfunction-associated steatotic liver disease. [PDF]
Chen H+19 more
europepmc +1 more source
Association of thrombospondin-1 with the actin cytoskeleton of human thrombin-activated platelets through an αIIbβ3- or CD36-independent mechanism [PDF]
Anne Saumet+3 more
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Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
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Oxidative Stress in Antigen Processing and Presentation
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang+9 more
wiley +1 more source