Candida albicans is a major fungal pathogen whose virulence is linked to filamentation. Its close relative, C. dubliniensis, filaments less efficiently and causes disease more rarely. To explore regulatory differences, we created C. dubliniensis mutants lacking transcription regulator orthologs that have been associated with filamentation in C ...
Teresa Meza‐Davalos+2 more
wiley +1 more source
Weight Loss‐Associated Remodeling of Adipose Tissue Immunometabolism
ABSTRACT Obesity is a multifactorial condition characterized by excessive adiposity and systemic chronic low‐grade inflammation. Recent literature reflects a growing appreciation for the complex interplay between metabolism and the immune system in the pathogenesis of obesity‐related health conditions.
Paulo José Basso+5 more
wiley +1 more source
CD36 as an Oxidized LDL Receptor-Insight from CD36 Deficient Subjects
Shuichi Nozaki+2 more
openalex +2 more sources
The Landscape of Cancer Metabolism as a Therapeutic Target
ABSTRACT Cancer cells reprogram their metabolism during progression to adapt to the tumor microenvironment, which is characterized by distinct differences in nutrient availability, oxygen concentrations, and acidity. This metabolic reprogramming can simultaneously create metabolic vulnerabilities unique to cancer cells, making cancer metabolism a ...
Kenji Ohshima
wiley +1 more source
CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism [PDF]
Maria Febbraio+2 more
openalex +1 more source
Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids [PDF]
Abumrad, Nada A.+2 more
core +2 more sources
CD36, a Member of the Class B Scavenger Receptor Family, as a Receptor for Advanced Glycation End Products [PDF]
Nobutaka Ohgami+6 more
openalex +1 more source
Environmental modulators of vascular physiology and inflammation
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne+3 more
wiley +1 more source
A role for CD36 in the regulation of dendritic cell function [PDF]
Britta C. Urban+2 more
openalex +1 more source
Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes [PDF]
Huang, Xiaoheng+6 more
core +2 more sources