Results 241 to 250 of about 83,609 (361)

CD36 does not play a direct role in HDL or LDL metabolism [PDF]

, 2001
Willem J.S. de Villiers, Lei Cai, Nancy R. Webb, Maria C. de Beer, Deneys R. van der Westhuyzen, Frederick C. de Beer   +5 more
openalex   +1 more source

Cellular Senescence in Cancer: Mechanisms, Roles in Tumor Progression, and Therapeutic Implications

MedComm – Oncology, Volume 4, Issue 3, September 2025.
Senescent tumor cells in TME exhibit dual roles. “Angels” secrete SASPs/DAMPs to boost immunological clearance and antitumor immunity via MHC‐I upregulation; “Demons” produce tumor‐promoting SASPs recruiting MDSCs to drive malignancy. ABSTRACT Cellular senescence, a state of irreversible cell cycle arrest accompanied by a senescence‐associated ...
Jingrui Yan, Yu Zhang, Guohua Mao, Jun Yu, Tianxing Zhou, Jihui Hao   +5 more
wiley   +1 more source

Cytoadherence of Plasmodium falciparum-Infected Erythrocytes Is Mediated by a Redox-Dependent Conformational Fraction of CD36 [PDF]

, 2001
Paola Gruarin, Luca Primo, Chiara Ferrandi, Federico Bussolino, Narendra N. Tandon, Paolo Arese, Daniela Ulliers, Massimo Alessio   +7 more
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, Volume 15, Issue 8, Page 1246-1266, August 2025.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, Volume 12, Issue 29, August 7, 2025.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

CD36 attenuates pressure overload-induced myocardial insulin resistance via HSF1-dependent HSP90α suppression and competitive disruption of the HSP90α-InsR complex. [PDF]

J Transl Med
Shu H, Li N, Zhao Q, Zhang Z, Qin Y, Nie J, Wang DW, Zhou N.   +7 more
europepmc   +1 more source

GREM1 deficiency induced bone marrow adipose niche promotes B‐cell acute lymphoblastic leukemia disease progression

International Journal of Cancer, Volume 157, Issue 3, Page 559-572, 1 August 2025.
What's new? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song, Rui Zhang, Liya Pan, Qiang Mi, Yi Yang, Xiang Wang, Yani Ma, Shuhong Shen, Benshang Li, Yanxin Li, Li Hong   +10 more
wiley   +1 more source

Induction of fatty acid translocase/CD36, peroxisome proliferator-activated receptor-gamma2, leptin, uncoupling proteins 2 and 3, and tumor necrosis factor-alpha gene expression in human subcutaneous fat by lipid infusion.

, 2000
Enzo Nisoli, Michele O. Carruba, Cristina Tonello, C. Macor, Giovanni Federspil, Roberto Vettor   +5 more
openalex   +1 more source

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

, 2010
A-Gonzalez, Albert, Albert, Aujla, Benson, Bluestone, Coombes, Fadok, Fadok, Finnemann, Finnemann, Freire-de-Lima, Hall, Hanayama, Hanayama, Hanayama, Hoffmann, Hsu, Huang, Huynh, Hynes, Ivanov, Ivanov, Jang, Johann, Kleinclauss, Lacy-Hulbert, Liang, Lucas, Lucas, Majai, McCarty, Miyake, Mucida, Mukundan, Nagata, Nandrot, Nishihara, Rubartelli, Savill, Savill, Savill, Schambach, Siewert, Stuart, Sugimoto, Torchinsky, Travis, Urban, Voll, Wu   +50 more
core   +1 more source

Identification of new selective CD36 inhibitors to potentiate HER2-targeted therapy in HER2-positive breast cancer. [PDF]

Sci Rep
Castagnoli L, Bonì F, Bigliardi M, Toneguzzo P, Corsetto PA, Galasso G, Franceschini A, Cocomazzi P, Regondi V, Capuzzoni C, Rizzo AM, Ligorio F, Vernieri C, Seneci P, Arosio D, Tagliabue E, Mastrangelo E, Milani M, Pupa SM.   +18 more
europepmc   +1 more source