Results 21 to 30 of about 83,609 (361)

Endothelial cell CD36 regulates membrane ceramide formation, exosome fatty acid transfer and circulating fatty acid levels

open access: yesNature Communications, 2023
Endothelial cell (EC) CD36 controls tissue fatty acid (FA) uptake. Here we examine how ECs transfer FAs. FA interaction with apical membrane CD36 induces Src phosphorylation of caveolin-1 tyrosine-14 (Cav-1Y14) and ceramide generation in caveolae ...
V. Peche   +10 more
semanticscholar   +1 more source

The activated CD36-Src axis promotes lung adenocarcinoma cell proliferation and actin remodeling-involved metastasis in high-fat environment

open access: yesCell Death and Disease, 2023
Obesity/overweight and lipid metabolism disorders have become increased risk factors for lung cancer. Fatty acid translocase CD36 promotes cellular uptake of fatty acids.
Li-Zhong Liu   +10 more
semanticscholar   +1 more source

FABP4 Controls Fat Mass Expandability (Adipocyte Size and Number) through Inhibition of CD36/SR-B2 Signalling

open access: yesInternational Journal of Molecular Sciences, 2023
Adipose tissue hypertrophy during obesity plays pleiotropic effects on health. Adipose tissue expandability depends on adipocyte size and number. In mature adipocytes, lipid accumulation as triglycerides into droplets is imbalanced by lipid uptake and ...
Emmanuelle Berger, A. Géloën
semanticscholar   +1 more source

Chlorogenic Acid Alleviates LPS-Induced Inflammation and Oxidative Stress by Modulating CD36/AMPK/PGC-1α in RAW264.7 Macrophages

open access: yesInternational Journal of Molecular Sciences, 2023
Chlorogenic acid (CGA) is a bioactive substance with anti-inflammatory activities. Clusters of CD36 have been suggested to be widely involved in inflammatory damage.
T. Gu   +8 more
semanticscholar   +1 more source

Plasma levels of CD36 and glutathione as biomarkers for ruptured intracranial aneurysm

open access: yesOpen Life Sciences, 2023
Evidence has proved that intracranial aneurysm (IA) formation and rupture might be closely related to inflammatory response and oxidative stress. Our objective was to evaluate the potential of CD36 and glutathione (GSH) as biomarkers for IA.
Wang Hanbin   +7 more
doaj   +1 more source

CD36-mediated metabolic crosstalk between tumor cells and macrophages affects liver metastasis

open access: yesNature Communications, 2022
Macrophage-mediated immune suppression contributes to poor outcome in liver metastasis. Here the authors show that CD36-expressing metastasis associated macrophages engulf tumor cell-derived extracellular vesicles enriched in long-chain fatty acids ...
Ping Yang   +15 more
semanticscholar   +1 more source

Soluble CD36− a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? [PDF]

open access: yesArchives of Physiology and Biochemistry, 2011
CD36 is a class B scavenger receptor observed in many cell types and tissues throughout the body. Recent literature has implicated CD36 in the pathogenesis of metabolic dysregulation such as found in obesity, insulin resistance, and atherosclerosis.
Koonen, Debby P Y   +2 more
openaire   +4 more sources

CD36 Signaling in Diabetic Cardiomyopathy

open access: yesAging and disease, 2021
Cluster of differentiation 36 (CD36), also referred to as scavenger receptor B2, has been shown to serve multiple functions in lipid metabolism, inflammatory signaling, oxidative stress, and energy reprogramming. As a scavenger receptor, CD36 interacts with various ligands, such as oxidized low-density lipoprotein (oxLDL), thrombospondin 1 (TSP-1), and
Chen Chen   +4 more
openaire   +3 more sources

Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?

open access: yesCell Death and Disease, 2020
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic steatohepatitis (NASH) which can progress to cirrhosis and hepatocellular carcinoma ...
P. Rada   +3 more
semanticscholar   +1 more source

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