Results 111 to 120 of about 1,186,345 (240)

Investigating human platelet antigens and antibodies in pregnancy: An 11‐year experience from a Canadian reference laboratory

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Foetal and neonatal alloimmune thrombocytopaenia (FNAIT) is a potentially severe immune‐mediated condition that is believed to be under‐identified in the Canadian population. The Canadian Blood Services National Platelet Immunology Reference Laboratory (NPIRL) serves as a centralized referral laboratory for FNAIT ...
Bryan Tordon, Gwen Clarke, Jacqueline Wong, Ann Peregrin, Akash Gupta   +4 more
wiley   +1 more source

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]

, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core   +4 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, Volume 20, Issue 3, Page 753-778, March 2026.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Polysaccharides from the Chinese medicinal herb Achyranthes bidentata enhance anti-malarial immunity during Plasmodium yoelii 17XL infection in mice [PDF]

, 2012
Background Clinical immunity to malaria in human populations is developed after repeated exposure to malaria. Regulation and balance of host immune responses may lead to optimal immunity against malaria parasite infection.
Xiaotong Zhu, Yanyan Pan, Li Zheng, Liwang Cui, Yaming Cao   +4 more
core   +2 more sources

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du, Rui Deng, Ya Wu, Hong‐Xia Ren, Zong‐Hong Lin, Yang‐Bao Miao   +5 more
wiley   +1 more source

A new transfectant panel cell line‐based MoAb‐independent antigen capture assay system for detection of CD36 antibody

Vox Sanguinis, 2014
Background and ObjectivesCD36 antibody (Ab) causes several disorders: neonatal alloimmune thrombocytopenia, platelet transfusion refractoriness and non‐haemolytic transfusion reactions. However, there is no gold‐standard test for CD36 Ab.Materials and MethodsWe developed a transfectant panel cell line‐based MoAb‐independent antigen capture assay system
E, Amakishi, T, Hayashi, Y, Koh, N, Matsuyama, H, Ishii, H, Matsukura, K, Yasui, F, Hirayama   +7 more
openaire   +3 more sources

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid, Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Grassia, Gianluca, Hansson, Göran K., Harrison, James E., Hugues, Stéphanie, Ludewig, Burkhard, Maffia, Pasquale, Mallat, Ziad, Masters, Leanne M., Murphy, Deirdre, Reith, Walter, Reizis, Boris, Sabir, Suleman, Sage, Andrew P.   +16 more
core   +2 more sources

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

In Human Dermis, Ultraviolet Radiation Induces Expansion of a CD36+ CD11b+ CD1- Macrophage Subset by Infiltration and Proliferation; CD1+ Langerhans-Like Dendritic Antigen-Presenting Cells are Concomitantly Depleted

Journal of Investigative Dermatology, 1995
Antigen-presenting (APC), suppressor T-cell-inducing macrophages infiltrate both human and murine epidermis after ultraviolet radiation (UVR) exposure. To determine their derivation, we prepared epidermal cell and dermal cell suspensions from human keratome biopsy specimens obtained from nonexposed skin and from UVB-irradiated sites (3 d after four ...
Meunier, Laurent, Bata-Csorgo, Zsuzsanna, Cooper, Kevin D.   +2 more
openaire   +2 more sources

Severe malaria: what's new on the pathogenesis front? [PDF]

, 2016
Plasmodium falciparum causes the most severe and fatal form of malaria in humans with over half a million deaths each year. Cerebral malaria, a complex neurological syndrome of severe falciparum malaria, is often fatal and represents a major public ...
Grau, Georges Emile Raymond, Wassmer, Samuel Crocodile   +1 more
core   +1 more source